Short- and long-term outcomes of laparoscopic surgery for intestinal Behcet’s disease: a comparative study with open surgery

2015 ◽  
Vol 30 (1) ◽  
pp. 99-105 ◽  
Author(s):  
Se Jin Baek ◽  
Seung Hyuk Baik ◽  
Chang Woo Kim ◽  
Min Soo Cho ◽  
Hyun A. Jang ◽  
...  
Keyword(s):  
Laparoscopic Surgery ◽  
Comparative Study ◽  
Open Surgery ◽  
Behcet’S Disease ◽  
Long Term Outcomes ◽  
Intestinal Behçet’S Disease ◽  
Short And Long Term ◽  
Intestinal Behcet’S Disease ◽  
Intestinal Behçet's Disease

Mucosal Healing Predicts the Long-Term Prognosis of Intestinal Behçet’s Disease

2014 ◽  
Vol 59 (10) ◽  
pp. 2529-2535 ◽  
Author(s):  
Sun Mie Yim ◽  
Duk Hwan Kim ◽  
Hyun Jung Lee ◽  
Hui Won Jang ◽  
Soo Jung Park ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Mucosal Healing ◽  
Intestinal Behçet’S Disease ◽  
Behcet's Disease ◽  
Intestinal Behcet’S Disease ◽  
Long Term Prognosis ◽  
Intestinal Behçet's Disease

scholarly journals Long-Term Efficacy of Adalimumab in Patients With Intestinal Behcet’s Disease: Eight Consecutive Cases

2016 ◽  
Vol 8 (4) ◽  
pp. 334-337 ◽  
Author(s):  
Satoshi Tanida ◽  
Tsutomu Mizoshita ◽  
Hirotada Nishie ◽  
Keiji Ozeki ◽  
Takahito Katano ◽  
...  
Keyword(s):  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Intestinal Behçet’S Disease ◽  
Behcet's Disease ◽  
Term Efficacy ◽  
Intestinal Behcet’S Disease ◽  
Intestinal Behçet's Disease

scholarly journals Clinical Features and Long-Term Prognosis of Intestinal Behçet's Disease after Surgery

2018 ◽  
Vol 71 (3) ◽  
pp. 133-138
Author(s):  
Ichiro Ise ◽  
Kazuhiro Wtanabe ◽  
Munenori Nagao ◽  
Shinobu Ohnuma ◽  
Hideaki Karasawa ◽  
...  
Keyword(s):  
Clinical Features ◽  
Behçet’S Disease ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Intestinal Behçet’S Disease ◽  
Behcet's Disease ◽  
Intestinal Behcet’S Disease ◽  
Long Term Prognosis ◽  
Intestinal Behçet's Disease

Laparoscopic versus open surgery for locally advanced rectal cancer following neoadjuvant chemoradiotherapy with S-1: Short- and long-term outcomes of multicenter prospective phase II trials.

2018 ◽  
Vol 36 (4_suppl) ◽  
pp. 793-793
Author(s):  
Takao Hara ◽  
Tomonori Akagi ◽  
Shinichiro Empuku ◽  
Kentaro Nakajima ◽  
Iwaki Kentaro ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Laparoscopic Surgery ◽  
Open Surgery ◽  
Locally Advanced ◽  
Advanced Rectal Cancer ◽  
Locally Advanced Rectal Cancer ◽  
Phase Ii Trials ◽  
Long Term Outcomes ◽  
Short And Long Term

793 Background: We have reported the effectiveness of neoadjuvant radiotherapy (RT) combined with S-1 in terms of compliance and pathologic response for locally advanced rectal cancer. In the present study, we aimed to evaluate the safety and efficacy of laparoscopic surgery for locally advanced rectal cancer following neoadjuvant RT combined with S-1 in comparison with open surgery. Methods: Two multicenter prospective phase II trials were conducted (UMIN003396, UMIN003398). A total of 63 patients with locally advanced rectal cancer classified as T3-4, N0-3, and M0 were enrolled, and neoadjuvant RT combined with S-1 and total mesorectal excision with D3 lymphadenectomy was performed. Of these, 57 patients were analyzed and divided into a laparoscopic group (LAP, n = 43) and open group (OP, n = 14). We evaluated the short- and long-term outcomes of laparoscopic surgery compared with open surgery by univariate and multivariate analyses. Results: In the patient background, there were no significant differences between the two groups except that cases with T3 and N0 were significantly higher in the LAP compared with the OP. In the operative findings, operation time was longer (mean 447 min vs. 352 min, p = 0.007) and blood loss was lesser (median 220 ml vs. 485 ml, p = 0.033) in the LAP than those in the OP. Although there were no significant differences observed in the incidence of perioperative and late complications between the two groups, reoperation within 30 days was significantly less in the LAP compared with the OP (1 case vs. 5 cases, p = 0.0004). In the multivariate analysis, a distance of the tumor from anal verge within 3 cm was the independent risk factor for reoperation within 30 days. Furthermore, estimated 5-year disease-free survival (LAP 72 % vs. OP 73 %, p = 0.945) and 5-year overall survival (LAP 76 % vs. 75 %, p = 0.836) didn’t significantly differ between the two groups in the Kaplan–Meier curve. Conclusions: The findings of this study demonstrated that laparoscopic surgery for locally advanced rectal cancer following neoadjuvant RT combined with S-1 could be an optional procedure in terms of short- and long-term outcomes. Clinical trial information: UMIN000003396, UMIN000003398.

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