scholarly journals Psychoneuroendocrinological effects of music therapy versus mindfulness in palliative care: results from the ‘Song of Life’ randomized controlled trial

2021 ◽  
Author(s):  
Friederike Koehler ◽  
Jens Kessler ◽  
Martin Stoffel ◽  
Martin Weber ◽  
Hubert J. Bardenheuer ◽  
...  
Keyword(s):  
Heart Rate ◽  
Palliative Care ◽  
Music Therapy ◽  
Therapy Group ◽  
Controlled Trial ◽  
Psychosocial Interventions ◽  
Subjective Distress ◽  
Stress Biomarkers ◽  
Patient Reported ◽  
Mean Heart Rate

Abstract Purpose Although research on psychosocial interventions in palliative care provided evidence for their effectiveness regarding patient-reported outcomes, few studies have examined their psychobiological effects yet. Therefore, the purpose of the present work as part of an overarching study was to investigate differential effects of music therapy versus mindfulness on subjective distress and both neuroendocrine and autonomic stress biomarkers. Methods A total of 104 patients from two palliative care units were randomly assigned to three sessions of either music therapy or mindfulness. Before and after the second session (completed by 89 patients), participants rated their momentary distress and provided three saliva samples for cortisol and α-amylase analysis. Furthermore, photoplethysmography recordings were continuously assessed to calculate mean heart rate and heart rate variability. Data were analyzed using multilevel modeling of all available data and sensitivity analysis with multiply imputed data. Results Between 67 and 75% of the maximally available data points were included in the primary analyses of psychobiological outcomes. Results showed a significant time*treatment effect on distress (b =  − 0.83, p = .02) indicating a greater reduction in the music therapy group. No interaction effects were found in psychobiological outcomes (all p > .05), but multilevel models revealed a significant reduction in cortisol (b =  − 0.06, p = .01) and mean heart rate (b =  − 7.89, p = .05) over time following either intervention. Conclusion Findings suggest a beneficial effect music therapy on distress while no differential psychobiological treatment effects were found. Future studies should continue to investigate optimal stress biomarkers for psychosocial palliative care research. Trial Registration German Clinical Trials Register (DRKS)—DRKS00015308 (date of registration: September 7, 2018)

scholarly journals Mobile-Assisted Cognitive Behavioral Therapy for Negative Symptoms: Open Single-Arm Trial With Schizophrenia Patients

10.2196/24406 ◽  
2020 ◽  
Vol 7 (12) ◽  
pp. e24406
Author(s):  
Eric Granholm ◽  
Jason Holden ◽  
Kristen Dwyer ◽  
Tanya Mikhael ◽  
Peter Link ◽  
...  
Keyword(s):  
Cognitive Behavioral Therapy ◽  
Negative Symptoms ◽  
Behavioral Therapy ◽  
Therapy Group ◽  
Controlled Trial ◽  
Psychosocial Interventions ◽  
Cognitive Behavioral ◽  
Unmet Treatment Need ◽  
Attitude Model ◽  
Persistent Negative Symptoms

Background Negative symptoms are an important unmet treatment need for schizophrenia. This study is a preliminary, open, single-arm trial of a novel hybrid intervention called mobile-assisted cognitive behavioral therapy for negative symptoms (mCBTn). Objective The primary aim was to test whether mCBTn was feasible and could reduce severity of the target mechanism, defeatist performance attitudes, which are associated with experiential negative symptoms and poor functioning in schizophrenia. Methods Participants with schizophrenia or schizoaffective disorder (N=31) who met prospective criteria for persistent negative symptoms were enrolled. The blended intervention combines weekly in-person group therapy with a smartphone app called CBT2go. The app extended therapy group skills, including recovery goal setting, thought challenging, scheduling of pleasurable activities and social interactions, and pleasure-savoring interventions to modify defeatist attitudes and improve experiential negative symptoms. Results Retention was excellent (87% at 18 weeks), and severity of defeatist attitudes and experiential negative symptoms declined significantly in the mCBTn intervention with large effect sizes. Conclusions The findings suggest that mCBTn is a feasible and potentially effective treatment for experiential negative symptoms, if confirmed in a larger randomized controlled trial. The findings also provide support for the defeatist attitude model of experiential negative symptoms and suggest that blended technology-supported interventions such as mCBTn can strengthen and shorten intensive psychosocial interventions for schizophrenia. Trial Registration ClinicalTrials.gov NCT03179696; https://clinicaltrials.gov/ct2/show/NCT03179696

Effects of Guitar Accompaniment Patterns on Hospitalized Infants: A Randomized Controlled Trial

2021 ◽  
Author(s):  
Kory Antonacci ◽  
Nicole Steele ◽  
Jacob Wheatley ◽  
Donna M Weyant ◽  
Beverly Brozanski ◽  
...  
Keyword(s):  
Heart Rate ◽  
Randomized Controlled Trial ◽  
Music Therapy ◽  
Neonatal Intensive Care ◽  
Controlled Trial ◽  
Pain Scale ◽  
Post Intervention ◽  
Randomized Controlled ◽  
Stressful Environment ◽  
The Difference

Abstract A neonatal intensive care unit (NICU) can be an extremely stressful environment for infants receiving complex medical care at a pediatric facility. Music therapy can help address the stressful environment by increasing comfort and relaxation as well as decreasing a patient’s physiological response of heart rate and respiratory rate. A randomized controlled trial was completed, examining the effects of 2 guitar accompaniment patterns on infants (an arpeggiated pattern and a bass/chord pattern) in a NICU. There were 180 infants enrolled with mean chronological ages of 7.4 ± 6.1 weeks and postmenstrual ages (gestational age at birth + their chronological age) of 39.8 ± 7.9 weeks. All subject enrollees participated in a 12-minute initial music therapy session. Outcome measures included heart rate, respirations, and comfort responses. The results of the research study demonstrated that the arpeggiated guitar pattern had a lower mean heart rate and respiratory across all 3 data points (pre, during, and post intervention); however, the difference in means between the 2 accompaniment pattern groups was not statistically significant. Using the Neonatal Infant Pain Scale (NIPS) to measure comfort response, the results demonstrated no difference between the 2 group accompaniment patterns. Although the results show no significant differences among accompaniment pattern groups, the researchers describe the clinical significance that supports the use of both accompaniment patterns as suitable interventions for infants in the NICU receiving music therapy intervention.

scholarly journals Complementary music therapy for cancer patients in at-home palliative care and their caregivers: protocol for a multicentre randomised controlled trial

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Inmaculada Valero-Cantero ◽  
Francisco Javier Martínez-Valero ◽  
Milagrosa Espinar-Toledo ◽  
Cristina Casals ◽  
Francisco Javier Barón-López ◽  
...  
Keyword(s):  
Palliative Care ◽  
Randomised Controlled Trial ◽  
Music Therapy ◽  
Cancer Patients ◽  
Controlled Trial ◽  
Randomised Controlled ◽  
At Home

scholarly journals Music Therapy Reduces Pain in Palliative Care Patients: A Randomized Controlled Trial

2013 ◽  
Vol 45 (5) ◽  
pp. 822-831 ◽  
Author(s):  
Kathy Jo Gutgsell ◽  
Mark Schluchter ◽  
Seunghee Margevicius ◽  
Peter A. DeGolia ◽  
Beth McLaughlin ◽  
...  
Keyword(s):  
Palliative Care ◽  
Randomized Controlled Trial ◽  
Music Therapy ◽  
Controlled Trial ◽  
Randomized Controlled

scholarly journals Stress and Fatigue Management Using Balneotherapy in a Short-Time Randomized Controlled Trial

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Lolita Rapolienė ◽  
Artūras Razbadauskas ◽  
Jonas Sąlyga ◽  
Arvydas Martinkėnas
Keyword(s):  
Music Therapy ◽  
Effect Size ◽  
Therapy Group ◽  
Controlled Trial ◽  
Geothermal Water ◽  
Control Group ◽  
Stress Symptoms ◽  
General Physical ◽  
Short Time ◽  
And Control

Objective. To investigate the influence of high-salinity geothermal mineral water on stress and fatigue.Method. 180 seamen were randomized into three groups: geothermal (65), music (50), and control (65). The geothermal group was administered 108 g/L salinity geothermal water bath for 2 weeks five times a week. Primary outcome was effect on stress and fatigue. Secondary outcomes were the effect on cognitive function, mood, and pain.Results. The improvements after balneotherapy were a reduction in the number and intensity of stress-related symptoms, a reduction in pain and general, physical, and mental fatigue, and an improvement in stress-related symptoms management, mood, activation, motivation, and cognitive functions with effect size from 0.8 to 2.3. In the music therapy group, there were significant positive changes in the number of stress symptoms, intensity, mood, pain, and activity with the effect size of 0.4 to 1.1. The researchers did not observe any significant positive changes in the control group. The comparison between the groups showed that balneotherapy was superior to music therapy and no treatment group.Conclusions. Balneotherapy is beneficial for stress and fatigue reduction in comparison with music or no therapy group. Geothermal water baths have a potential as an efficient approach to diminish stress caused by working or living conditions.

scholarly journals Estimation of the effects of music therapy on the anxiety and patient’s perception during an upper gastrointestinal endoscopy procedure: a randomised controlled trial

2020 ◽  
Vol 8 (7) ◽  
pp. 2594
Author(s):  
Vikram Kannan ◽  
Sumathy Sundar ◽  
Sajeesh Manikanda Prabhu ◽  
G. Ezhumalai
Keyword(s):  
Music Therapy ◽  
Therapy Group ◽  
Controlled Trial ◽  
Control Group ◽  
Gi Endoscopy ◽  
Group 2 ◽  
Randomised Controlled ◽  
Upper Gastrointestinal ◽  
Therapy Intervention ◽  
Group 1

Background: An upper gastrointestinal (GI) endoscopy procedure is an invasive medical procedure that is used in diagnosis and treatment of various intestinal disorders. Patients posted for upper GI endoscopy procedures often experience significant levels of pre-procedural fear, anxiety and discomfort during the procedure which can negatively affect cooperation levels during the procedure with the attending doctor. A very few studies have explored the beneficial effects of music therapy in this regard and so our study was planned.Methods: A prospective randomised controlled trial was conducted with a sample of 54 patients who were enrolled for this study. They were randomly divided into two groups - group 1 consisting of 27 patients, receiving a music therapy intervention and group 2 consisting of 27 patients who served as a control group. Group 1 received a receptive music therapy intervention in the form vocal, relaxing, improvisational music with patient preferred chants for fifteen minutes before and during the endoscopy procedure. Group 2 did not receive a music therapy intervention.Results: The results indicated that the post intervention, state-anxiety levels was significantly lower in the music therapy group compared to the control group with (p=0.001). Patients’ cooperation levels during the procedure with the attending doctor was significantly higher in the music therapy group than in the control group (p=0.001).Conclusions: Repeated music therapy intervention is highly beneficial in reducing state anxiety levels and improving cooperation levels during the GI endoscopy procedure.

scholarly journals Association between Respiratory and Heart Rate Fluctuations and Death Occurrence in Dying Cancer Patients: Continuous Measurement with a Non-wearable Monitor

2021 ◽  
Author(s):  
Sakiko Fukui ◽  
Kasumi Ikuta ◽  
Isseki Maeda ◽  
Satoshi Hattori ◽  
Yutaka Hatano ◽  
...  
Keyword(s):  
Heart Rate ◽  
Palliative Care ◽  
Respiratory Rate ◽  
Cancer Patients ◽  
Care Staff ◽  
Heart Rates ◽  
Dying Patients ◽  
Imminent Death ◽  
Mean Heart Rate ◽  
At Home

Abstract Background: The cancer deaths at home and in care facilities are increasing worldly. If we can identify imminent death using a monitoring device and inform it to family members and care staff, it will help them, even in the absence of healthcare professionals at all times. We examined the association between impending death and continual changes in respiratory and heart rates measured by a non-wearable monitor every minute for the final 2 weeks of dying cancer patients. In this longitudinal study, we enrolled patients in a palliative-care-unit and continuously measured their respiratory/heart rates by a monitor, capturing their other vital signs and clinical status from medical records.Result: A dataset was created with 240 patient-days from every minute data to death (345,600 data) among 24 patients for 3-14 days to death. We analyzed this 240 patient-day data. After confirming the associations between the value of death day (n=24) or other days (2–14 days before death, n=216) and the mean, maximum, minimum, and variance of respiratory and heart rates every 24 hours by univariate analyses, we conducted a repeated measures logistic regression analysis using a generalized estimating equation. Finally, the maximum respiratory rate and mean heart rate were significantly associated with death at 24, 48, and 72 hours later, other than the respiratory rate of the last 24 hours.Conclusion: The maximum respiratory rate and mean heart rate measured every minute by a monitor can warn imminent death during the last days of life among dying patients. Our findings can help for caregivers to aware imminent death among dying patients at home or in facilities, in collaboration with palliative care professionals.

Biomarcadores de estresse em recém-nascidos pré-termos expostos ao banho: estudo piloto

2019 ◽  
Vol 17 (1) ◽  
pp. 12
Author(s):  
Patrícia De Freitas ◽  
Amélia Fumiko Kimura
Keyword(s):  
Heart Rate ◽  
Oxygen Saturation ◽  
Salivary Cortisol ◽  
Cortisol Concentration ◽  
Routine Practice ◽  
Preterm Newborn ◽  
Stress Biomarkers ◽  
The Mean ◽  
Preterm Newborns ◽  
Mean Heart Rate

Introduction: the corporal hygiene of the preterm newborn, although it is a recommended and routine practice, requires caution and safety for provoking disorganization in the autonomic system and homeostasis imbalance. Aim: to evaluate the variation of heart rate, oxygen saturation and salivary cortisol levels of preterm newborns submitted to conventional immersion baths and swaddled in sheets. Method: this is a randomized, pilot, cross-over clinical trial with 15 clinically stable preterm newborns. Results: the mean heart rate and oxygen saturation after the conventional immersion bath and swaddled in sheet did not present significant clinical and statistical differences. There was an increase in the salivary cortisol concentration when comparing the pre and post-bath values in the two bath techniques. Conclusion: there were no significant differences in stress biomarkers when comparing the two bathing techniques.

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