Capillary refill time, bleeding time, clotting time, erythrocyte sedimentation rate and prothrombin time in natural cases of canine Trypanosoma congolense infection

2016 ◽  
Vol 26 (1) ◽  
pp. 175-179
Author(s):  
Prince Obi Obiorah ◽  
Iniobong Chukwuebuka Ikenna Ugochukwu ◽  
Emmanuel Ikenna Ugochukwu
2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S80-S80
Author(s):  
Constance Nwadike ◽  
Amarachi Nwakamma ◽  
Harrison Nwanjo ◽  
Denis Nwosu ◽  
Roy Ezekwe

Abstract Objectives The evidence supporting the role of circulating markers of inflammation in the pathogenesis of atria fibrillation remains controversial. This study investigated the levels of serum lipids, C-reactive proteins, erythrocyte sedimentation rate, prothrombin time, and platelet count in subjects with new-onset atria fibrillation (NAF), but with no established cardiac disease, in a Nigerian community. Methods The case control study involved a total of 200 subjects: 110 subjects with NAF and 90 apparently healthy subjects without AF, as control. AF was confirmed by a 12-lead electrocardiogram (ECG), while excluding subjects with high risk. Blood samples from the subjects were analyzed for the following parameters: C-reactive proteins using ELISA method and serum lipids using an enzymatic, colorimetric method; erythrocyte sedimentation rate, by Westergreen method; platelet count using a Midray hematology auto analyzer; and the prothrombin time using a tissue thromboplastin method. Data collected from the result were analyzed using SPSS version 15. Results There was a significant increase in the levels of C-reactive proteins and ESR in subjects with NAF when compared with the control subjects. A significant increase was observed in the mean values of total cholesterol and low-density lipoproteins in subjects with NAF, while that of high-density lipoproteins was lower in NAF than in controls. There was no significant difference in the mean values of triglyceride in NAF and the control. Results also showed significantly reduced prothrombin time, with more platelet count in subjects with NAF. The result demonstrated that females (56.3%) had greater risk of developing AF than males (45.8%), while incidence of AF was observed to increase with age. Conclusion The results of the markers assayed suggest marked dyslipidemia, inflammation, and thrombogenesis in subjects with new-onset AF. Hence dyslipidemia and inflammation play critical roles in the pathogenesis of atria fibrillation.


2021 ◽  
pp. 57-62
Author(s):  
Iyevhobu Kenneth Oshiokhayamhe ◽  
Amaechi R. A. ◽  
Turay A. A. ◽  
Okobi T. J. ◽  
Usoro E. R. ◽  
...  

An estimated 50,000 Nigerian women die each year from complications of pregnancy and childbirth, accounting for 10% of global estimates of pregnancy maternal death with about 2% resulting from drug induction. This cross-sectional study sets out to evaluate the Prothrombin time test (PT), activated partial thromboplastin time test (aPTT) Erythrocyte sedimentation rate (ESR), and Platelet count (PC) of pregnant women attending antenatal clinics at Oredo Health Centre in Benin City, Edo State. A total number of 130 subjects comprising 100 pregnant women and 30 non-pregnant women were recruited for the study. Prothrombin time (PT), Activated Partial Thromboplastin Time (APTT), Platelet count and Erythrocyte Sedimentation Rate (ESR) were studied using standard manual methods. The prothrombin time (sec) of the pregnant women 1st trimester (19.12±0.77b), 2nd trimester (19.90±1.02 b) and 3rd trimester (19.66±0.56 b), activated partial thromboplastin time (sec) 1st trimester (44.02±1.17 b), 2nd trimester (47.72±1.47 b) and 3rd trimester (45.88±1.10b), Erythrocyte sedimentation rate (mm/hr) 1st trimester (24.37±3.04 a), 2nd trimester (37.83±4.53 a) and 3rd trimester (43.25±5.24 a) and platelet count (X109/L) 1st trimester (248.29±23.18a), 2nd trimester (236.33±13.84 b) and 3rd trimester (239.10±16.07 a) were significantly higher than the prothrombin time (sec) 16.48±0.81 a, activated partial thromboplastin time (sec) 36.53±1.42 a, ESR (mm/hr) 29.83±4.14 a and platelet count (X109/L) 201±9.54 an of the non-pregnant women (p<0.05). The ESR (mm/hr) of the 3rd trimester (43.25±5.24) was observed to be significantly higher than that of the 1st trimester (24.37±3.04) and 2nd trimester (37.83±4.53) (p<0.05). Our investigation showed that antibiotics in pregnancy have a deleterious effect on PT, ESR, APTT and PC studied. We recommend that pregnant women should be given due attention throughout the course and events of pregnancy to prevent or reduce the risk of thrombotic episodes and possible disseminated intravascular coagulation (DIC) with resultant better maternity/child safety and health outcome and educated on the effects of antibiotics to pregnancy.


2012 ◽  
Vol 3 (1) ◽  
pp. 17-19
Author(s):  
MO Faruqe ◽  
MR Alam ◽  
MER Bhuiyan ◽  
M Myenuddin

To evaluate the certain haematobiochemical parameters in different ages of Hubbard Classic broiler birds, the study was performed at Kazi Farms Ltd., Gazipur in collaboration with the Department of Physiology, Bangladesh Agricultural University, Mymensingh for a period of one month (1st to 30th March 2002). On haematobiochemical examination, total erythrocyte count, haemoglobin content, packed cell volume, clotting time, glucose and uric acid concentration were gradually increased with advancement of age of birds. The values of TEC, Hb, PCV, clotting time, glucose and uric acid were recorded at day old birds as average 1.23 ± 0.02 million / cmm, 3.90 ± 0.09 g%, 19.60± 0.24 % , 37.20 ± 1.50 second, 179.20 ± 8.95 mg / dl and 3.72 ± 0.58 mg / dl respectively while the values at day 30 were 2.43 ± 0.07 million / cmm, 7.26 ± 0.16 g%, 28.20 ± 0.58%, 206.40 ± 10.17 second, 271.60 ± 8.56 mg / dl and 6.42 ± 0.65 mg / dl respectively which were found statistically significant (p < 0.01). On the other hand erythrocyte sedimentation rate, cholesterol and urea concentration were gradually decreased where significantly (p < 0.05) higher values (2.80 ± 0.20 mm in 1st hour, 330.40 ± 38.52 mg / dl and 26.42 ± 2.06 mg/ dl respectively) were recorded at day old chicks and lower values (1.80 ± 0.37 mm in 1st hour, 104.20 ± 3.24 mg / dl and 17.00 ± 0.07 mg / dl respectively) were recorded at age of 30 days old of birds. The findings of the present work clearly indicate that age has got influential effect on the body haemopoietic system of the broiler birds as well as haematobiochemical values.


2008 ◽  
Vol 24 (5) ◽  
pp. 351
Author(s):  
Young Ki Kim ◽  
Seong Woo Hong ◽  
Jung Woo Chun ◽  
Yeo Goo Chang ◽  
In Wook Paik ◽  
...  

2021 ◽  
pp. 1-7
Author(s):  
Zahra Soleimani ◽  
Fatemeh Amighi ◽  
Zarichehr Vakili ◽  
Mansooreh Momen-Heravi ◽  
Seyyed Alireza Moravveji

BACKGROUND: The diagnosis of osteomyelitis is a key step of diabetic foot management. Procalcitonin (PCT) is a novel infection marker. This study aimed to investigate the diagnostic value of procalcitonin and other conventional infection markers and clinical findings in diagnosis of osteomyelitis in diabetic foot patients. METHODS AND MATERIALS: This diagnostic value study was carried out on ninety patients with diabetic infected foot ulcers admitted in Kashan Beheshti Hospital, 2016. After obtaining consent, 10 cc blood sample was taken for measuring serum PCT, CBC, ESR, CRP and FBS. Clinical characteristics of the wounds were noted. Magnetic resonance imaging of the foot was performed in all patients to diagnose osteomyelitis. All statistical analyses were done with the use of SPSS-16. RESULTS: PCT levels were 0.13 ± 0.02 ng/mili patients with osteomyelitis (n= 45) and 0.04 ± 0.02 ng/ml in patients without osteomyelitis (n= 45). PCT, Erythrocyte sedimentation rate and C-reactive protein was found significantly higher in patients with osteomyelitis (p< 0.001). The ROC curve was calculated for PCT. The area under the ROC curve for infection identification was 1 (p< 0.001). The best cut-off value for PCT was 0.085 ng/ml. Sensitivity, specificity, and positive and negative predictive values were 100%, 97.8%,97.8% and 100%, respectively. CONCLUSION: In this group of patients, PCT was useful to discriminate patients with bone infection. Also, Erythrocyte sedimentation rate and C-reactive protein can be used as a marker of osteomyelitis in diabetic patients.


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