Formulation And Antioxcidant Activity Test Of Clay Mask Extracted Ethanol Tamarillo (Solanum betaceum Cav.)

Tamarillo (Solanum betaceum Cav.) is a plant that is spread in Java, Bali and North Sumatra, which is rich in nutrients and contain flavonoid as antioxidants that can prevent cell damage due to oxidative stress. Clay-based face masks have a firming and cleansing effect on the skin. Tamarillo was extracted by maceration method using 96% ethanol extract, phytochemical screening was carried out. Clay mask formulation with extract concentration of 1.5%, 2%, 2.5% and blanks. Physical quality test of clay mask preparations included homogeneity test, stability test, pH test, dry time test, irritation test, effectiveness test of clay mask preparation on volunteers using the Skin Analyzer Checkher (Aram), preference test and antioxidant test using the DPPH method. The results showed that the ethanol extract tamarillo contained alkaloids, flavonoids, saponins and could be formulated into a clay mask preparation that was homogeneous, stable, met the pH requirements, and dried time. The results of the effectiveness test using a checkher skin analyzer give the effect of reducing blemishes, reducing pores, moisturizing, not causing irritation to the skin. The antioxidant activity of the ethanol extract tamarillo were in the moderate category with an IC50 value of 201 g/mL and the clay mask preparation of the ethanol extract tamarillo with a concentration of 2.5% was in the medium category with an IC50 value of 221 g/mL.

Evaluation of Reaction Time on Karate Athletes UKM Syiah Kuala University

The purpose of the study. Reaction time is a determining factor in sports, especially in martial arts. The purpose of this study is to evaluate the reaction time of UKM Karate athletes at Syiah Kuala University. Materials and methods. The approach in this study uses a quantitative approach. The sampling technique used purposive sampling, which means this technique is used to achieve certain goals. The samples in this study were athletes from UKM karate at Syiah Kuala University. The data collection technique was carried out by using the whole body reaction test to measure the reaction time of the athlete's arms and legs. Results. results of the research in the form of a whole body reaction test, the results using the formula for the average value and the total percentage can be concluded: (1) The arm reaction time test with the total average value for male athletes is 0.169 seconds and female athletes are 0.173, and the highest percentage is in the very good category, amounting to 87% for male and female athletes, 75% in the very good category and (2) the limb reaction time test has an average value of 0.269 seconds for male athletes and female athletes of 0.361 seconds, with the highest percentage value amounted to 100% in the good category for male athletes and for female athletes it was in the sufficient category with a percentage of 50%. Conclusions. the analysis show that most athletes have been able to maintain and increase reaction time well, to be able to improve and maintain it, regular and continuous training is needed

New stage of scientific understanding of homeopathic phenomenon

Statements that homeopathy failed scientific testing and that it is a mock-science based on placebo effect are frequent in modern mass media. Their authors disregard not only results of many studies but also the effect of homeopathy in coma patients, infants, animals, germs and plants. Homeopathy is criticised due to lack of statistically acceptable studies and an accepted effect mechanism laid out in principles of modern science. However, homeopathy not only stood the time test but also showed potential for further implementation. Scientific studies, active use of homeopathy in medical practice help to resolve crisis in modern therapy by of treatment and prevention cost efficiency

Feasibility of Cognitive-Motor Exergames in Geriatric Inpatient Rehabilitation: A Pilot Randomized Controlled Study

Objective: The aim of this pilot randomized clinical trial was to test the feasibility and efficacy of an exergame-based cognitive-motor training program in geriatric inpatients.Methods: The study participants were randomly allocated to either the exergame intervention group or the control group. The control group received the standard rehabilitation treatment offered in the clinic. In addition to the standard rehabilitation program, the intervention group conducted supervised exergame training on 5 days per week using the Dividat Senso, an exergame system specifically designed for older adults. The primary outcome was feasibility, as measured by e.g., adherence rate, attrition rate, occurrence of adverse events, System Usability Scale (SUS) and NASA-TLX score. Secondary outcomes included measures of physical and cognitive functioning such as comfortable walking speed, maximal walking speed, dual task walking speed, Short Physical Performance Battery (SPPB), Timed Up and Go test (TUG), Color-Word Interference test (D-KEFS), Trail Making test A and B (TMT), Go/No-Go test and Step Reaction Time test (SRTT). All secondary outcome measures were assessed pre- and post-intervention.Results: Thirty-nine persons were included in the study. Average adherence rate was 99%, there were no intervention-related dropouts and no adverse events. The mean System Usability Scale (SUS) score was 83.6 and the mean NASA-TLX score 45.5. Significant time-group interaction effects were found for the dual task walking speed, the Go/No-Go test and Step Reaction Time test (SRTT).Conclusion: Exergaming is a feasible, safe and effective cognitive-motor training approach in inpatient rehabilitation of geriatric patients. Incorporating exergaming in the rehabilitation program of geriatric patients offers potential to reduce fall risk factors and to increase patients’ exercise motivation and rehabilitation success.

Integrated Lateral and Longitudinal Control with Optimization-Based Allocation Strategy for Autonomous Electric Vehicles

This paper presents a novel approach for path-following control of a four-wheeled autonomous vehicle. The rear wheels of the vehicle are driven independently, all four wheels can be braked independently, and the front wheels are steered together. The proposed cascade structure consists of two convex optimization-based parts: one for path-following and another for the control allocation problem of the actuators. The control algorithm presents cost functions for the allocation problem focusing on safety. The proposed cost functions were examined and compared to former ones in a simulation environment. After all, the controller was tested in real-time test on a Lotus Evora test vehicle developed by ThyssenKrupp.

Karakterisasi Sifat Fisik Granul Dengan Bahan Pengikat Amylum Manihot Pragelatinasi Dan Polivinilpirolidon

Granules come from small particles which then become single larger particles to form a lump. The binder in the granules is used to ensure the incorporation of the powder particles in the granules. Manihot starch is a natural binder and polyvinylpyrrolidone is a synthetic binder, because manihot starch has poor flow properties, it is necessary to modify it by pregelatination. The purpose of this study was to determinethe characterization of the physycal properties of granules with a natural binder of pregelatinized starch manihot and and synthetic polyvinylpyrrolidone on the physical properties of the granules. Variations in the concentration of pregelatinated starch manihot were 3% and 5% respectively. The granulation process is carried out by mixing all materials that have easy flowing properties. The resulting granules were evaluated for their physical properties and then the data were analyzed using SPSS with the One Way ANOVA method with a 95% confidence level. The results of the organoleptic test are white granules but on F1 and F2 there are brown spots then round shape and characteristic odor, the flow time meets the requirements of 10 g/second, the angle of repose test meets the requirements <30˚, compressibility meets the requirements <15%. The results of statistical analysis showed a significant difference (sig <0,05) in the flow time test. The optimum concentration of pregelatiansi manihot starch is 5% (F2) and polyvinylpyrrolidone 5% (F4). The Suggest for further researchers can use other natural excipients and make modifications to improve the physical characteristics of the granules. Keyword: Amylum Manihot; granules;polivinilpirolidon; pragelatination AbstrakGranul berasal dari partikel-partikel yang berukuran kecil kemudiam menjadi partikel tunggal yang lebih besar membentuk suatu gumpalan. Bahan pengikat pada granul digunakan untuk menjamin penyatuan partikel serbuk dalam granul. Amilum manihot merupakan pengikat bahan alami dan polivinilpirolidon merupakan pengikat bahan sintetis, dikarenakan amilum manihot memiliki sifat alir yang kurang baik maka perlu dilakukan modifikasi dengan pragelatinasi. Tujuan dari penelitian ini untuk mengetahui karakterisasi sifat fisik granul dengan bahan pengikat alami amilum manihotpragelatinasi dan bahan sintetis polivinilpirolidon. Variasi konsentrasi bahan pengikat masing-masing adalah 3% dan 5%. Proses granulasi dilakukan dengan mencampurkan seluruh bahan yang memiliki sifat mudah mengalir. Granul yang dihasilkan di evaluasi sifat fisiknya kemudian data dianalisis menggunakan SPSS dengan metode One Way ANOVA dengan tingkat kepercayaan 95%. Hasil uji organoleptisgranulbewarna putih namun pada F1 dan F2 terdapat bintik coklat kemudian bentuk bulat dan bau khas, waktu alir memenuhi syarat ≤10 g/detik, uji sudut diam memenuhi syarat <30˚, kompresibilitas memenuhi syarat <15%. Hasil analisis statistik terdapat perbedaan bermakna (sig < 0,05) pada uji waktu alir.Konsentrasi optimum bahan pengikat amylummanihotpragelatiansi 5% (F2) dan polivinilpirolidon 5% (F4). Saran untuk peneliti selanjutnya dapat digunakan bahan eksipien alami yang lainnya dan dilakukan modifikasi untuk meningkatkan karakteristik sifat fisik granul. Kata kunci: Amilum Manihot; granul;polivinilpirolidon; pragelatinasi

Test method for opening and closing time of 500kV high voltage circuit breaker under double terminal grounding condition

The opening and closing time test of 500kV high voltage circuit breaker can evaluate the mechanical characteristics and three-phase synchronization performance of the circuit breaker. Due to the influence of the earth resistance circuit, the traditional test method of circuit breaker opening and closing time can not be carried out when both ends are grounded. This paper first introduces the differential coil used to collect the signal, and then according to the requirements of field test, puts forward a test method for the opening and closing time of circuit breaker under the condition of double terminal grounding, and gives the basis for judging the opening and closing signal time. Finally, it compares and analyses the results of this method with the traditional high voltage circuit breaker opening and closing time test method, and obtains the conclusion of high voltage circuit breaker. The test method of grounding time division and closing time at both ends of the circuit breaker can fully meet the needs of field maintenance, which provides a new idea for the opening and closing time test of 500kV high voltage circuit breaker.

Prüfung der Stabilität von Implantat-Abutment-Verbindungen im Rotationsschwinger-Test

ZusammenfassungUntersuchungen hinsichtlich der Stabilität des Implantat-Abutment-Verbundes gibt es bislang lediglich in Anlehnung an die genormte Prüfmethode nach DIN 14801. Es besteht jedoch zusätzlicher Bedarf an Prüfmethoden, die allein schon aus Gründen der Qualitätssicherung in vergleichsweise kurzen Zeitintervallen eine Stabilitätsprüfung dentaler Implantate ermöglichen. Daher sollte ein alternatives Testverfahren auf der Basis des in der Technik etablierten Rotationsschwinger-Tests nach DIN 1311–2 auf seinen praktischen Wert als „Life-Time-Test“ für Implantatsysteme untersucht werden. Durch 2 Versuchsprotokolle mit 30 bzw. 60 Ncm Auslenkmoment wurden unter- und überschwellige Belastungssituationen an 8 verschiedenen Implantat-Abutment-Systemen simuliert und morphologische Veränderungen sowie letztlich die Bruchfestigkeit der jeweils 6 getesteten Prüfkörper untersucht. Dabei änderte sich die Rotationsfreiheit des Abutments signifikant von ursprünglich 1–2° auf bis zu 6°. Das Lösedrehmoment der Abutmentschraube gab abhängig vom Anzugsdrehmoment signifikant um 10–45% nach. Aufweitungen von bis zu 0,2 mm der Implantathals-Region zeigten sich lediglich bei Frialit-2-Implantaten. Abutmentfrakturen traten in 35% der Fälle auf. Es zeigte sich, dass im Rotationsschwinger-Test innerhalb sehr kurzer Zeit ähnliche Schäden am Implantat-Abutment-Verbund auftreten, wie dies nach jahrelangem Gebrauch von Implantaten auch der Fall ist.

The Physical Activity Level and Reaction Time During Covid 19 Pandemic

The outbreak of the COVID-19 pandemic has a huge global impact in terms of public health, economic activities, employment, psychological and social life. The educational system had to adapt to the conditions imposed by avoiding the spread of coronavirus among pupils and students. The purpose of this study is to find out if the level of physical activity influence the reaction time using dominant and non-dominant hand. We collected data from 83 students (age ranged between 15–24 years; M = 49, f = 34) who participated to the study voluntarily. To measure physical activity index we have used three items about type of physical activity performed, frequency and duration. In addition, to measure reaction time we have used Reaction Time Test and Aim Trainer Test. Each student completed and assessed himself the questionnaire and the tests online. Data were recorded and analysed in SPSS (version 20.0). The level of physical activity relieved that 18,1% of subjects are very active, 26,5% are active, 20,5% have an acceptable level of physical activity, 12% are insufficient active, and 22,9% are sedentary. The values of reaction time for both tests are fastest for subjects with insufficient level of physical activity for dominant hand. The sedentary person are fasted reaction time with non-dominant hand in Reaction Time Test, and the very active subjects are fasted reaction time in Aim Trainer Test. The results has limitations, conducted by speed of Internet connection, and type of devise used in performing tests.

Frequency of Dry Eye in Glaucoma Patients Using Topical Anti-Glaucoma Therapy

Aim: To determine the prevalence of dry eye in glaucoma patients using topical anti-glaucoma therapy. Study Design: Descriptive observational study Place and duration of study: Department of Ophthalmology, Shalimar Medical & Dental College Lahore from 1st November 2020 to 30th April 2021. Methodology: Ninety patients of both genders were enrolled. Detailed demographics of enrolled cases age, sex and body mass index were recorded after taking informed written consent. Patients using topical anti-glaucoma therapy for more than 8 months and having symptoms of stinging and burning sensations itching, watering, irritation, due to regular use of topical antiglaucoma drugs were presented. Basal Schrimer’s test and tear film break-up time test was used to measure the frequency of dry eye syndrome as mild, moderate and severe. Results: There were 60 (66.7%) females and 30 (33.3%) patients were males. Mean age of the patients were 45.61±7.66 years with mean BMI 26.24±8.71 kg/m2. We found that 40 (44.4%) patients had burning and stinging sensations, itching found in 21 (23.3%), dry eye sensations were found in 16 (17.8%) patients and watering and irritation found in 13 (14.4%) .According to tear film break-up time test 20 (22.2%) cases did not show dry eye syndrome and 19 (21.1%) patients were normal in Basal Schrimer’s test. Conclusion: Use of topical anti-glaucoma medication resulted in dry eye syndrome as well as a decrease in the tear film's stability. Keywords: Anti-glaucoma therapy, Basal Schrimer`s test, Tear film break-up time, Anti-glaucoma therapy, Dry eye syndrome