Fasting plasma glucose is a stronger predictor of diabetes than triglyceride–glucose index, triglycerides/high-density lipoprotein cholesterol, and homeostasis model assessment of insulin resistance: Tehran Lipid and Glucose Study

2018 ◽  
Vol 55 (10) ◽  
pp. 1067-1074 ◽  
Author(s):  
Maryam Tohidi ◽  
Aidin Baghbani-Oskouei ◽  
Noushin Sadat Ahanchi ◽  
Fereidoun Azizi ◽  
Farzad Hadaegh
Author(s):  
Jae-Min Park ◽  
Jee-Yon Lee ◽  
Jae June Dong ◽  
Duk-Chul Lee ◽  
Yong-Jae Lee

AbstractBackground:Studies have suggested the triglyceride to high-density lipoprotein cholesterol ratio (TG/HDL-C) as a surrogate marker of insulin resistance. However, few studies have examined the association between TG/HDL-C and insulin resistance in the general adolescent population. This study aimed to examine the association between TG/HDL-C and insulin resistance in a nationally representative sample of Korean adolescents.Methods:A total of 2649 participants aged 12–18 years were selected from the 2007 to 2010 Korean National Health and Nutrition Examination Survey (KNHANES). Insulin resistance was defined as the homeostatic model assessment of insulin resistance (HOMA-IR) values greater than the 80th percentile.Results:The mean values of most cardiometabolic variables increased proportionally with TG/HDL-C quartiles. Compared to individuals in the lowest TG/HDL-C quartile, the odds ratio for insulin resistance for individuals in the highest quartile was 2.91 in boys and 2.38 in girls after adjusting for confounding variables.Conclusions:This study suggests that TG/HDL-C could be a convenient marker for identifying Korean adolescents with insulin resistance.


2018 ◽  
Vol 10 (46) ◽  
pp. 5493-5498
Author(s):  
Zhigang Li ◽  
Xifa Lan ◽  
Xiaoxiao Jiang ◽  
Qiaoyun Wang ◽  
Zhenhe Ma ◽  
...  

The triglyceride (TG) to high density lipoprotein cholesterol ratio (TG/HDL-C) and the TG level itself have both been identified as a biomarker of insulin resistance, cardiovascular disease and a predictor for atherosclerosis.


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