The association between cigarette smoking and diabetic nephropathy in Chinese male patients

2018 ◽  
Vol 55 (11) ◽  
pp. 1131-1141 ◽  
Author(s):  
Qianqian Han ◽  
Shanshan Wang ◽  
Junlin Zhang ◽  
Rui Zhang ◽  
Ruikun Guo ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Cigarette Smoking ◽  
Male Patients ◽  
Chinese Male

scholarly journals Comparative Evaluation of Orthostatic Hypotension in Patients with Diabetic Nephropathy

2021 ◽  
pp. 1-7
Author(s):  
Gamze Aytaş ◽  
Rümeyza Kazancıoğlu ◽  
Ömer C. Elçioğlu ◽  
Meltem Gürsu ◽  
A. Serra Artan ◽  
...  
Keyword(s):  
Diabetic Nephropathy ◽  
Orthostatic Hypotension ◽  
Electronic Device ◽  
Channel Blockers ◽  
Factors Affecting ◽  
Clinical Criteria ◽  
Measure Blood Pressure ◽  
Significant Difference ◽  
Male Patients ◽  
Very High

<b><i>Introduction:</i></b> Orthostatic hypotension (OH) affects 5–20% of the population. Our study investigates the presence of OH in diabetic nephropathy (DNP) patients and the factors affecting OH in comparison with nondiabetic chronic kidney disease (NDCKD) patients. <b><i>Method:</i></b> Patients presented to the nephrology clinic, and those who consented were included in the study. DNP was defined by kidney biopsy and/or clinical criteria. NDCKD patients of the same sex, age, and eGFR were matched to DNP patients. Demographic parameters and medications were obtained from the records. OH was determined by Mayo clinic criteria. The same researcher used an electronic device to measure blood pressure (BP). All samples were taken and analyzed the same day for biochemical and hematologic parameters and albuminuria. <b><i>Results:</i></b> 112 (51 F, 61 M, mean age: 62.56 ± 9.35 years) DNP and 94 (40 F, 54 M, mean age: 62.23 ± 10.08 years) NDCKD patients were included. There was no significant difference between DNP and NDCKD groups in terms of OH prevalence (70.5 vs. 61.7%, <i>p</i> = 0.181). Male patients had significantly higher OH prevalence than female patients (74.7 vs. 60.0%, <i>p</i> = 0.026). There was no significant difference in change in systolic BP between the groups (24.00 [10.00–32.00] mm Hg vs. 24.00 [13.75–30.25] mm Hg, <i>p</i> = 0.797), but the change in diastolic BP was significantly higher in the DNP group (8.00 [2.00–13.00] mm Hg vs. 6.00 [2.00–9.00] mm Hg, <i>p</i> = 0.025). In the DNP group, patients with OH had significantly higher uric acid levels than those without OH (7.18 ± 1.55 vs. 6.36 ± 1.65 mg/dL, <i>p</i> = 0.017). And, 73.7% of patients on calcium channel blockers developed OH (<i>p</i> = 0.015), and OH developed in 80.6% of 36 patients on alpha-blockers (<i>p</i> = 0.049). <b><i>Conclusion:</i></b> OH prevalence is very high in CKD, and etiology of CKD does not have a statistically significant effect on the frequency of OH, despite a difference that could be meaningful clinically. Therefore, patients with CKD are checked for OH, with or without concurrent diabetes mellitus. Evaluation of postural BP changes should be a part of nephrology practice.

scholarly journals A three-microRNA signature for lung squamous cell carcinoma diagnosis in Chinese male patients

Oncotarget ◽  
2017 ◽  
Vol 8 (49) ◽  
pp. 86897-86907 ◽  
Author(s):  
Lan Zhang ◽  
Xia Shan ◽  
Jun Wang ◽  
Jun Zhu ◽  
Zebo Huang ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Lung Squamous Cell Carcinoma ◽  
Male Patients ◽  
Chinese Male

scholarly journals CARD8 rs2043211 Polymorphism is Associated with Gout in a Chinese Male Population

2015 ◽  
Vol 35 (4) ◽  
pp. 1394-1400 ◽  
Author(s):  
Ying Chen ◽  
Xianfeng Ren ◽  
Changgui Li ◽  
Shichao Xing ◽  
Zhengju Fu ◽  
...  
Keyword(s):  
Renal Calculus ◽  
Genotype Distribution ◽  
Male Population ◽  
Chinese Han ◽  
Increased Risk ◽  
Phenotype Analysis ◽  
Obvious Association ◽  
Male Patients ◽  
Chinese Male ◽  
Control Study

Background &Aim: Previous studies have suggested genetic factors are involved in the development of gout. We performed a case-control study to investigate the genetic association between CARD8 rs2043211 polymorphism and gout. Methods: A total of 396 male patients with gout and 403 age- and sex- matched healthy controls were included in this study. Genotyping was performed using TaqMan SNP Genotyping Assays. An association analysis was carried out using the χ2 test. The genotype-phenotype analysis was also conducted. Results: The genotype distribution of CARD8 rs2043211 polymorphism confirmed to HWE in the controls (P = 0.27). There was an obvious difference in the genotype distribution of CARD8 rs2043211 polymorphism between cases and controls (P = 0.017). In addition, there was an obvious association between CARD8 rs2043211 polymorphism and gout under the recessive comparison model (AA vs. TT/TA: OR = 0.65, 95%CI 0.47-0.88, P = 0.006). Patients carrying genotype TT of CARD8 rs2043211 polymorphism had higher triglycerides levels compared to those carrying the AA genotype (2.77±2.08 mmol/L vs. 2.07±1.15 mmol/L, P = 0.01). Patients with the TT genotype also had significantly higher systolic blood pressure compared with those with the AA genotype (142.11±21.10 mmHg vs. 135.38±14.66 mmHg, P = 0.03). Patients carrying TT genotype also had an increased risk of renal calculus compared with those carrying the AA genotype. Conclusion: CARD8 rs2043211 polymorphism is significantly associated with susceptibility to gout in Chinese Han males.

Cigarette Smoking and Diabetic Nephropathy

2000 ◽  
pp. 85-93 ◽  
Author(s):  
M. Krimholtz ◽  
S. Thomas ◽  
G.C. Vibreti
Keyword(s):  
Diabetic Nephropathy ◽  
Cigarette Smoking

scholarly journals Effect of Cigarette Smoking on Urinary Podocyte Excretion in Early Diabetic Nephropathy

Diabetes Care ◽  
2003 ◽  
Vol 26 (4) ◽  
pp. 1324-1325 ◽  
Author(s):  
T. Nakamura ◽  
Y. Kawagoe ◽  
H. Koide
Keyword(s):  
Diabetic Nephropathy ◽  
Cigarette Smoking ◽  
Early Diabetic Nephropathy

Association of cigarette smoking with cognitive impairment in male patients with chronic schizophrenia

2020 ◽  
Vol 237 (11) ◽  
pp. 3409-3416
Author(s):  
Shuochi Wei ◽  
Dongmei Wang ◽  
Gaoxia Wei ◽  
Jiesi Wang ◽  
Huixia Zhou ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Cigarette Smoking ◽  
Chronic Schizophrenia ◽  
Male Patients

Facial emotion recognition and alexithymia in Chinese male patients with deficit schizophrenia

2016 ◽  
Vol 246 ◽  
pp. 353-359 ◽  
Author(s):  
Xiao Wei Tang ◽  
Miao Yu ◽  
Wei Wei Duan ◽  
Xiang Rong Zhang ◽  
Wei Wei Sha ◽  
...  
Keyword(s):  
Emotion Recognition ◽  
Facial Emotion Recognition ◽  
Facial Emotion ◽  
Deficit Schizophrenia ◽  
Male Patients ◽  
Chinese Male
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