The Effect of Flavonoid Consumption on Blood Pressure: A Systematic Review

Hypertension is a common condition in which the long-term force of blood against artery walls is high enough to cause health problems, such as heart disease eventually. High blood pressure is known as the "silent killer". Most people with high blood pressure are unaware of the problem because it may not have any warning signs or symptoms. For this reason, it is essential to measure blood pressure regularly. A new study has shown that consuming foods rich in flavonoids can help patients with high blood pressure. This advantage of these compounds is due to their vasodilator properties. Flavonoids are a diverse group of biologically active polyphenol compounds found in plants and herbs. Regular consumption of flavonoids has cardioprotective effects and may reduce the onset or progression of many cardiovascular diseases, especially hypertension. The article search was done in PubMed, ScienceDirect, and Google Scholar databases. The current body of evidence supports the ingestion of flavonoids for their beneficial effect on blood pressure. However, more significant research should further investigate the vascular moderating effects and the safety and acceptability of almond consumption.

How Sociodemographic Factors Impact the Utilization of Recommended Clinical Preventive Screening Services in Poland: A Nationwide Cross-Sectional Study

Cardiovascular disease (CVD) and cancer are the most frequent causes of mortality in Poland. To date, no study in Poland has attempted to analyze the impact of sociodemographic factors on the utilization of all recommended preventive services for these diseases. To address this challenge, a nationwide cross-sectional study was conducted. One thousand adults aged 18 years or older were interviewed using computer-assisted telephone surveys conducted via random selection. A representative population was obtained in accordance with existing demographics per voivodeship in Poland. We assessed whether factors such as age, gender, body mass index (BMI), net income, household size, place of residence, and education impacted the odds ratio of utilizing recommended preventive services for CVD and cancer. We determined that elderly patients receive influenza vaccination, measure blood pressure, PSA concentration, glucose and lipid profiles, and undergo colonoscopy and mammography more often than younger counterparts. Men were more often influenza vaccinated (OR = 1.56, 95% CI: 1.07–2.27) than women, while women measured blood glucose more often than men (OR = 0.62, 95% CI: 0.42–0.93). Furthermore, net income < 2000 PLN, BMI < 24 kg/m2 and at least secondary education level were found to be crucial predictors of undergoing mammography (OR = 2.16; 95% CI: 1.26–3.72), cervical smear tests (OR = 1.99, 95% CI: 1.24–3.17), and lipid measurements (OR = 1.76, 95% CI: 1.07–2.91), respectively. Educating people and financial support seem to play a crucial role in implementing novel campaigns and preventive programs in Poland. Addressing each significant factor may be of paramount importance in improving the receipt of preventive services and warranting greater preventive care coverage in the Polish population.

Penerapan Terapi Murottal Surat Al-Kahfi Untuk Penurunan Tekanan Darah Pada Pasien Hipertensi

Hypertension is a condition when systolic blood pressure is more than 140 mmHg and 90 mmHg in diastolic, by measuring several times at different times. One of the ways to maintain blood pressure is by using murottal therapy (listening Qur’an). The purpose of this case study was to measure blood pressure after listening Surah Al-Kahf in families with hypertension. The result of this study show that there was change in blood pressure of 160/100 mmHg decrease to 130/80 mmHg, while second patient who had a blood pressure of 170/100 mmHg drops 130/80 mmHg. These results indicate that murottal therapy is effective for maintaining blood pressure among hypertensive patients. Therefore, murottal therapy may be implemented independently by patient for a healthy lifestyle. Keywords: Hypertension, Surah Al-Kahf, Murottal Therapy AbstrakHipertensi merupakan tekanan darah yang tinggi lebih dari 140 mmHg pada nilai sistolik dan 90 mmHg pada nilai diastolik, dengan dilakukan beberapa kali pengukuran tekanan darah dalam waktu yang berbeda. Salah satu tindakan untuk menurunkan tekanan darah adalah terapi murottal surat Al-Kahfi. Tujuan dilakukan studi kasus ini untuk menguji penurunan tekanan darah menggunakan terapi murottal Surat Al-Kahfi pada keluarga dengan hipertensi. Metode yang digunakan adalah dengan menerapkan terapi murottal Surat Al-Kahfi. Hasil karya tulis ilmiah ini menunjukan adanya perubahan penurunan tekanan darah pada klien 1 dan klien 2. Klien 1 yang memiliki tekanan darah 160/100 mmHg turun menjadi 130/80 mmHg dan klien 2 memiliki tekanan darah 170/100 mmHg turun menjadi 130/80 mmHg.. Hasil tersebut menunjukkan bahwa terapi murottal surat Al-Kahfi efektif untuk menurunkan tekanan darah. Diharapkan klien dapat menerapkan terapi murottal secara mandiri dan dapat mengubah pola hidupnya menjadi pola hidup yang sehat.Kata kunci: Hipertensi, Surat Al-Kahfi, Terapi Murottal

Evaluation of the Accuracy of Cuffless Blood Pressure Measurement Devices: Challenges and Proposals

Several novel cuffless wearable devices and smartphone applications claiming that they can measure blood pressure (BP) are appearing on the market. These technologies are very attractive and promising, with increasing interest among health care professionals for their potential use. Moreover, they are becoming popular among patients with hypertension and healthy people. However, at the present time, there are serious issues about BP measurement accuracy of cuffless devices and the 2021 European Society of Hypertension Guidelines on BP measurement do not recommend them for clinical use. Cuffless devices have special validation issues, which have been recently recognized. It is important to note that the 2018 Universal Standard for the validation of automated BP measurement devices developed by the American Association for the Advancement of Medical Instrumentation, the European Society of Hypertension, and the International Organization for Standardization is inappropriate for the validation of cuffless devices. Unfortunately, there is an increasing number of publications presenting data on the accuracy of novel cuffless BP measurement devices, with inadequate methodology and potentially misleading conclusions. The objective of this review is to facilitate understanding of the capabilities and limitations of emerging cuffless BP measurement devices. First, the potential and the types of these devices are described. Then, the unique challenges in evaluating the BP measurement accuracy of cuffless devices are explained. Studies from the literature and computer simulations are employed to illustrate these challenges. Finally, proposals are given on how to evaluate cuffless devices including presenting and interpreting relevant study results.

The MPX5700AP Pressure Sensor Optimization for Blood Pressure Reading in The Design of Poltekad Electronic Detector Covid-19 (POLECTOR C-19) Using Oscillometer Method

- At the beginning of 2020 the world was shocked by the presence of a virus that attacks the respiratory tract, a virus known as Coronavirus Disease-2019 (Covid-19). Based on this problem, how does the system detect Covid-19 suspects based on blood pressure. In this study, researchers used a survey method which directly took data in the hospital. Therefore, the optimization of the MPX5700AP pressure sensor has been successfully made. At this time the researchers conducted a study that used the oscillometer method to measure blood pressure supported by Arduino Uno, which in waves will produce systolic and diastolic blood pressure. Blood pressure monitoring is made capable of measuring blood pressure in the range of 40-240 mmHg and this system has a systolic pressure error of 4.024 mmHg, while the diastolic pressure error is -0.408 mmHg.

A Digital Pressure Meter Equipped with Pressure Leak Detection

A manual sphygmomanometer is an instrument used to measure blood pressure, and consists of an inflatable cuff, a mercury manometer (or aneroid gauge) and an inflation ball and gauge. To assess the condition, accuracy and safety of mercury and anaeroid sphygmomanometers in use in general practice and to pilot a scheme for sphyg- momanometer maintenance within the district. Therefore, it must be calibrated periodically. Using the MPX 5050GP sensor as a positive pressure sensor. Requires a maximum pressure of 300 mmHg. This tool is also equipped with a SD Card as external storage. The display used in this module is TFT Nextion 2.8”. After conductings measurements of the three comparisons consisting of Multifunction, DPM and mercury tensimeter to 6 times, the smallest result 0 mmHg and the largest results 251.52 mmHg. While the error in mercury tensimeter’s of leak test to module and rigel is 0.56% and 0.404%.

Effect of Co-Administration of Curcumin with Amlodipine in Hypertension

Curcumin, a curcuminoid known as the main bioactive compound of turmeric, is used in foods, cosmetics, and pharmaceutical products. Amlodipine is a general antihypertensive drug used in combination with various other antihypertensive agents. To date, no studies have examined the effects of the co-administration of amlodipine with curcumin. In this study, the vasodilatory effects of curcumin, amlodipine, and the co-administration of curcumin with amlodipine on isolated rat aortic rings pre-contracted with phenylephrine were evaluated, and the hypotensive effects were evaluated using the tail cuff method. To measure blood pressure, male spontaneously hypertensive rats were divided into four groups, each containing six rats, as follows: amlodipine 1 mg/kg alone treated, amlodipine 1 mg/kg with curcumin 30 mg/kg treated, amlodipine 1 mg/kg with curcumin 100 mg/kg treated, and amlodipine 1 mg/kg with curcumin 300 mg/kg treated groups. Amlodipine and curcumin were intraperitoneally injected, and systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured at 1, 2, 4, and 8 h after administration. The combined administration of curcumin and amlodipine induced a stronger vasorelaxant effect than amlodipine alone. However, co-administration did not significantly lower SBP and DBP compared to the single administration of amlodipine. The results of this study suggest that hypertensive patients taking amlodipine can consume curcumin or turmeric for food or other medical purposes without inhibiting the blood pressure-lowering effect of amlodipine.

Clinical Impact of after-consult clinic blood pressure: comparison with automated office blood pressure

Background It is most important to measure blood pressure (BP) exactly in treating hypertension. Recent recommendations for diagnosing hypertension clearly acknowledge that an increase in BP attributable to the “whitecoat response” is frequently associated with manual BP recordings performed in community-based practice. However, there was no data about after-consult (AC) BP that could reduce whitecoat effect. So we evaluated before-consult (BC) and AC routine clinic BP and research based automated office blood pressure (AOBP) measured. Methods The study population consisted of 82 consecutive patients with hypertension between April 2019 and December 2019. We measured routine clinic BP and AOBP before and after see a doctor, respectively. Seated blood pressure and pulse are measured at each time after a rest period using an automated device as it offers reduced potential for observer biases. AOBP was measured and measuring BP 3 times un-observed. We compared each BP parameter for identifying exact resting BP state. Results There was significant difference between BC and AC systolic BP (135.37 ± 16.90 vs. 131.95 ± 16.40 mmHg, p = 0.015). However there was no difference in the BC and AC diastolic blood pressure (73.75 ± 11.85 vs. 74.42 ± 11.71 mmHg, p = 0.415). In the AOBP comparison, there was also significant difference (BC systolic AOBP vs. AC systolic AOBP, 125.17 ± 14.41 vs. 122.98 ± 14.09 mmHg, p = 0.006; BC diastolic ABOB vs. AC diastolic AOBP, 71.99 ± 10.49 vs. 70.99 ± 9.83, p = 0.038). Conclusions In our study, AC AOBP was most lowest representing resting state. Although AC BP was higher than BC AOBP, it might be used as alternative measurement for reducing whitecoat effect in the routine clinical practice.

Pemberdayaan Akseptor Dan Kader Mengenal Efek Samping Kontrasepsi Hormonal Di Pustu Tanjung Kabupaten Ende

ABSTRAK Peserta KB aktif dan akseptor KB baru di kabupaten Ende 53,2 %, lebih memilih menggunakan alat kontrasepsi hormonal sedangkan pemilihan alat kontrasepsi lain berada dibawah 20%. Alat kontrasepsi suntik yang paling banyak digunakan, berikutnya implant dan pil. Akseptor yang mengalami efek samping kenaikan berat badan dan hipertensi 32 orang (11,03%), dan akseptor terbanyak berada di Puskesmas pembantu Tanjung. Tujuan pengabdian masyarakat ini adalah pemberdayaan akseptor dan kader kesehatan mengenal efek samping penggunaan kontrasepsi hormonal, dimana sasarannya adalah kader dan akseptor. Metode yang digunakan adalah screening,ceramah, diskusi, simulasi dan praktikum oleh khalayak sasaran. Hasil pengabdian masyarakat menunjukan semua akseptor memiliki pengetahuan baik (83,33%) pada pretest sedangkan posttest (100%) namun belum tahu tentang lama penggunaan kontrasepsi hormonal baik secara suntik, implant dan pil. Keterampilan yang dicapai adalah semua kader dan akseptor 28 orang (100%) dapat mengukur tinggi badan, menimbang berat badan, dan mengukur tekanan darah. Diharapkan pengamatan yang intensif dari bidan Pustu Tanjung dan dapat diperdaya oleh kader KB untuk membantu mengawasi efek samping kontrasepsi hormonal. Kunci : Pemberdayaan akseptor dan kader, efek samping kontrasepsi hormonal. ABSTRACT 53.2% of active family planning participants and new family planning acceptors in the Ende district prefer to use hormonal contraceptives while the choice of other contraceptives is below 20%. The most widely used injectable contraceptives are implants and pills. There were 32 acceptors who experienced side effects of weight gain and hypertension (11.03%), and the most acceptors were in the Tanjung auxiliary health center. Research in Kumasi sub-district, Ghana, India, because some acceptors experienced long and heavy menstruation, spotting, no menstruation, and vaginal discharge so they were afraid of modern contraceptive methods (Kimberly Daniels, 2015). The aim of this community service is to empower acceptors and health cadres to recognize the side effects of using hormonal contraceptives, where the targets are cadres and acceptors. The methods used are screening, lectures, discussions, simulations, and practicum by the target audience. The results of community service show that all acceptors have good knowledge (83.33%) at pretest while posttest (100%), but they do not know about the length of time using hormonal contraceptives both by injection, implant, and pill. The skill achieved is that all 28 cadres and acceptors (100%) can measure height, weight body weight, and measure blood pressure. It is hoped that intensive observation from the midwife of Pustu Tanjung and the family planning cadres can help to monitor the side effects of hormonal contraception. Keywords: Empowerment of acceptors and cadres, side effects of hormonal contraception.

eBP

Frequent blood pressure monitoring is the key to diagnosis and treatments of many severe diseases. However, the conventional ambulatory methods require patients to carry a blood pressure (BP) monitoring device for 24 h and conduct the measurement every 10--15 min. Despite their extensive usage, wearing the wrist/arm-based BP monitoring device for a long time has a significant impact on users' daily activities. To address the problem, we developed eBP to measure blood pressure (BP) from inside user's ear aiming to minimize the measurement's impact on users' normal activities although maximizing its comfort level. The key novelty of eBP includes (1) a light-based inflatable pulse sensor which goes inside the ear, (2) a digital air pump with a fine controller, and (3) BP estimation algorithms that eliminate the need of blocking the blood flow inside the ear. Through the comparative study of 35 subjects, eBP can achieve the average error of 1.8 mmHg for systolic (high-pressure value) and -3.1 mmHg for diastolic (low-pressure value) with the standard deviation error of 7.2 mmHg and 7.9 mmHg, respectively. These results satisfy the FDA's AAMI standard, which requires a mean error of less than 5 mmHg and a standard deviation of less than 8 mmHg.