A cerium vanadate interconnected with a carbon nanofiber heterostructure for electrochemical determination of the prostate cancer drug nilutamide

2019 ◽  
Vol 186 (8) ◽  
Author(s):  
Thangavelu Kokulnathan ◽  
Raj Karthik ◽  
Shen-Ming Chen ◽  
Jeyaraj Vinoth Kumar ◽  
Subramanian Sakthinathan
Keyword(s):  
Prostate Cancer ◽  
Carbon Nanofiber ◽  
Electrochemical Determination ◽  
Cancer Drug ◽  
Cerium Vanadate

An electrochemical sensor based on a carbon paste electrode for the determination of buserelin

2020 ◽  
Vol 12 (1) ◽  
pp. 33-38 ◽  
Author(s):  
Marjan Fallah ◽  
Mostafa Rahimnejad ◽  
Maryam Asghary ◽  
Mehrdad Mashkour
Keyword(s):  
Prostate Cancer ◽  
Electrochemical Sensor ◽  
Carbon Paste Electrode ◽  
Electrochemical Determination ◽  
Cancer Drug ◽  
Carbon Paste ◽  
Paste Electrode

This study presents a rapid, simple, sensitive, and selective electrochemical sensor prepared using a carbon paste electrode for the electrochemical determination of buserelin—an anti-prostate cancer drug.

Three validated stripping voltammetric procedures for determination of the anti-prostate cancer drug flutamide in tablets and human serum at a mercury electrode

2004 ◽  
Vol 82 (9) ◽  
pp. 1386-1392 ◽  
Author(s):  
E Hammam ◽  
H S El-Desoky ◽  
K Y El-Baradie ◽  
A M Beltagi
Keyword(s):  
Prostate Cancer ◽  
Human Serum ◽  
Mercury Electrode ◽  
Stripping Voltammetry ◽  
Differential Pulse ◽  
Pharmaceutical Formulation ◽  
Cancer Drug ◽  
Linear Sweep ◽  
Square Wave

Flutamide is a nonsteriodal anti-androgen drug, which is commonly used in the treatment of advanced prostate cancer. Based on the reduction of the nitro organic moiety of the drug molecule in acetate buffer of pH 5 at the hanging mercury drop electrode, three adsorptive cathodic stripping voltammetric procedures were optimized for determination of flutamide in bulk, tablets, and human serum applying linear-sweep, differential-pulse, and square-wave waveforms. The achieved limits of detection of the bulk drug were 1.9 × 10–7, 8.7 × 10–8, and 9.7 × 10–9 mol L–1 by using the optimized differential-pulse, linear-sweep, and square-wave adsorptive stripping voltammetric procedures, respectively. Repeatability of the results was studied for 1 × 10–6 mol L–1 of the drug and the recoveries obtained were 98.51 ± 1.56% (LSV), 98.89 ± 0.87% (DPV), and 99.21 ± 1.03% (SWV). The proposed procedures were successfully applied to the determination of the drug in pharmaceutical formulation (Eulexin® tablets) and human serum. The detection limits of the drug in bulk, pharmaceutical formulation, and human serum achieved by means of the proposed procedures showed that the square-wave mode was more reliable for determination of the drug especially in its low concentration levels.Key words: flutamide, linear-sweep, differential-pulse, square-wave, cathodic adsorptive stripping voltammetry, determination, Eulexin® tablets, human serum.

Synthesis of graphene/carbon nanofiber for electrochemical determination of levodopa in the presence of uric acid

Ionics ◽  
2018 ◽  
Vol 25 (6) ◽  
pp. 2835-2843 ◽  
Author(s):  
Wan Qiu Wang ◽  
Hong Yan Yue ◽  
Ze Min Yu ◽  
Shuo Huang ◽  
Shan Shan Song ◽  
...  
Keyword(s):  
Uric Acid ◽  
Carbon Nanofiber ◽  
Electrochemical Determination
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