Human pegivirus 1 in Cabo Verde: prevalence and genotypic distribution among HIV-infected individuals

Author(s):  
Isabel Inês M. de Pina-Araujo ◽  
Marco Aurélio Horta ◽  
Francisco Campello do Amaral Mello ◽  
Caroline Cordeiro Soares
Author(s):  
Ana Suzete Dias Semedo ◽  
Arnaldo Fernandes Matos Coelho ◽  
Neuza Manuel Pereira Ribeiro
Keyword(s):  

Atualmente, a liderança assume um papel importante no seio organizacional, uma vez que o estilo de supervisão adotado pelos líderes pode influenciar, direta ou indiretamente, os comportamentos e atitudes dos colaboradores. Nesta perspetiva, este estudo empírico investiga como a liderança autêntica explica a felicidade e a criatividade dos colaboradores. O papel mediador da felicidade também será analisado. Participaram no estudo 543 colaboradores pertencentes a várias organizações em Cabo Verde. Foi utlizado os Modelos de Equações Estruturais para testar as hipóteses propostas. Os resultados mostram que as perceções de liderança autêntica predizem a criatividade tanto diretamente como através do papel mediador da felicidade dos colaboradores. Este estudo sugere que as perceções de liderança autêntica podem melhorar a felicidade dos colaboradores que, por sua vez, estimula a sua criatividade. Estes resultados podem ajudar os gestores a perceberem como aumentar a criatividade dos colaboradores através da autenticidade da sua liderança. A originalidade deste estudo centra-se na integração destes três conceitos num único estudo, fornecendo evidências sobre a relação entre a liderança autêntica e criatividade através da mediação da felicidade. Por outro lado, responde ao desafio proposto por alguns autores (por ex: Gardner, et al., 2011) da necessidade de mais investigação sobre a liderança autêntica e seu impacto nos colaboradores.


Author(s):  
Elson Artur Dias Santos ◽  
Cleiton da Silva Silveira
Keyword(s):  

2011 ◽  
Vol 3 (4) ◽  
Author(s):  
Érica Antunes Pereira
Keyword(s):  

Neste texto, procuro aliar minha pesquisa acerca da poesia de Vera Duarte -- especialmente de sua primeira obra, Amanhã amadrugada --, desenvolvida em nível de Doutorado na Universidade de São Paulo (USP), com bolsa da Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP), à perspectiva da própria autora, dialogando tanto sobre seu “fazer poético” quanto sobre a situação das mulheres cabo-verdianas na atualidade, e tomando como pontos de apoio a teoria da hermenêutica do cotidiano (DIAS, 1994; 1998) e a entrevista a nós concedida por Vera Duarte em Cabo Verde (Ilhas de Santiago e São Vicente), em dezembro de 2009.PALAVRAS-CHAVE: Literatura Cabo-verdiana, poesia; autoria feminina, Vera Duarte.


2016 ◽  
Vol 8 (15) ◽  
Author(s):  
Comissão Editorial

É com grande satisfação que a comissão editorial da Revista Mulemba torna pública sua edição 14.2, cujo objetivo principal é discutir as interseções existentes entre os domínios da oralidade e o da escrita. Já amplamente debatido ao longo da história dos estudos literários africanos, tal diálogo encontra, agora, uma nova possibilidade de apreciação, adensada tanto por novas perspectivas teóricas quanto pela escolha dos corpus que compõem os artigos de nossa revista. Ao abordarmos “A presença das culturas orais nas literaturas africanas de língua portuguesa”, reafirmamos nossa aposta por relevantes discussões que fomentem o estudo daquilo que é culturalmente produzido em Angola, Moçambique, Cabo Verde, São Tomé e Príncipe e Guiné-Bissau.


2020 ◽  
Vol 11 (1) ◽  
pp. 125-136
Author(s):  
Rogomenoma Alice Ouedraogo ◽  
Théodora Mahoukèdè Zohoncon ◽  
Ina Marie Angèle Traore ◽  
Abdoul Karim Ouattara ◽  
Sindimalgdé Patricia Guigma ◽  
...  

AbstractObjectivethis study was conducted to determine the distribution of high-risk human papillomavirus (HR-HPV) genotypes in women in the general population of three regions of Burkina Faso.MethodThis multicenter, descriptive cross-sectional study involved 1321 sexually active women in five cities in three regions of Burkina Faso: Central, Central-Eastern and Hauts-Bassins regions. After collection of endocervical specimens, pre-cervical lesions were screened by visual inspection with acetic acid and lugol (VIA / VILI). HR-HPV genotypes were characterized by multiplex real-time PCR after extraction of viral DNA.ResultsThe mean age of women was 31.98 ± 10.09 years. The HR-HPV infection in the three regions ranged from 26.16% to 43.26% with 35.42% as overall prevalence in women. The most common HR-HPV genotypes in descending order were: HPV 56, 52, 66, 59, 39, 51, 18, 35. The prevalence of bivalent vaccine genotypes (HPV16 / 18) was 7.83% against 63.78% of genotypes not covered by HPV vaccine; 36.32% (170/468) of women had multiple concomitant HR-HPV infections.Conclusionthis study showed significant regional variation and high prevalence of HR-HPV infection in women. The predominant genotypes differ from those covered by available vaccines in Burkina Faso. These results will help guide our health policies towards better prevention of cervical cancer. The diversity of oncogenic genotypes is sparking a large-scale study in the West African sub-region, particularly in cases of cancer and the introduction of the nonavalent vaccine which includes HPV 52 found among the predominant genotypes in this study.


2019 ◽  
Vol 5 (1) ◽  
Author(s):  
David Varillas Delgado ◽  
Juan José Tellería Orriols ◽  
Carlos Martín Saborido

Abstract Background The genetic profile that is needed to define an endurance athlete has been studied during recent years. The main objective of this work is to approach for the first time the study of genetic variants in liver-metabolizing genes and their role in endurance performance by comparing the allelic and genotypic frequencies in elite endurance athletes to the non-athlete population. Methods Genotypic and allelic frequencies were determined in 123 elite endurance athletes (75 professional road cyclists and 48 endurance elite runners) and 122 male non-athlete subjects (sedentary). Genotyping of cytochrome P450 family 2 subfamily D member 6 (CYP2D6 rs3892097), glutathione-S transferase mu isoform 1 (GSTM1), glutathione S-transferase pi (GSTP rs1695) and glutathione S-transferase theta (GSTT) genes was performed by polymerase chain reaction (PCR). The combination of the polymorphisms for the “optimal” polygenic profile has been quantified using the genotype score (GS). Results Statistical differences were found in the genetic distributions between elite endurance athletes and non-athletes in CYP2D6 (p < 0.001) and GSTT (p = 0.014) genes. The binary logistic regression model showed a favourable OR (odds ratio) of being an elite endurance runner against a professional road cyclist (OR: 2.403, 95% CI: 1.213–4.760 (p = 0.002)) in the polymorphisms studied. Conclusions Genotypic distribution of liver-metabolizing genes in elite endurance athletes is different to non-athlete subjects, with a favourable gene profile in elite endurance athletes in terms of detoxification capacity.


2021 ◽  
Vol 14 (3) ◽  
pp. 235
Author(s):  
Jen-Sheng Pei ◽  
Chao-Chun Chen ◽  
Wen-Shin Chang ◽  
Yun-Chi Wang ◽  
Jaw-Chyun Chen ◽  
...  

The purpose of our study was to investigate whether genetic variations in lncRNA H19 were associated with susceptibility to childhood leukemia. Two hundred and sixty-six childhood leukemia patients and 266 healthy controls were enrolled in Taiwan, and two single nucleotide polymorphisms (SNPs), rs2839698 and rs217727, in H19 were genotyped and analyzed. There was a significant difference in the genotypic distribution of rs2839698 between patients and healthy controls (p = 0.0277). Compared to the wild-type CC genotype, the heterozygous variant CT and homozygous variant TT genotypes were associated with significantly increased risks of childhood leukemia with an adjusted odd ratio (OR) of 1.46 (95% confidence interval (CI), 1.08–2.14, p = 0.0429) and 1.94 (95%CI, 1.15–3.31, p = 0.0169), respectively (pfor tread = 0.0277). The difference in allelic frequencies between childhood leukemia patients and controls was also significant (T versus C, adjusted OR = 1.53, 95%CI, 1.13–1.79, p = 0.0077). There were no significant differences in the genotypic and allelic distributions of rs217727 between cases and controls. Interestingly, the average level of H19 rs2839698 was statistically significantly higher for patients with CT and TT genotypes than from those with the CC genotype (p < 0.0001). Our results indicate that H19 SNP rs2839698, but not rs217727, may serve as a novel susceptibility marker for childhood leukemia.


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