scholarly journals Reduction of carbonyl compounds via hydrosilylation catalyzed by well-defined PNP-Mn(I) hydride complexes

2021 ◽  
Author(s):  
Stefan Weber ◽  
Dina Iebed ◽  
Mathias Glatz ◽  
Karl Kirchner
Keyword(s):  
Carbonyl Compounds ◽  
Hydrogen Donor ◽  
Synthetic Chemistry ◽  
Double Bonds ◽  
Reduction Reactions ◽  
Hydride Complexes ◽  
Unsaturated Compounds ◽  
Aldehydes And Ketones ◽  
Hydrogenation Reactions

AbstractReduction reactions of unsaturated compounds are fundamental transformations in synthetic chemistry. In this context, the reduction of polarized double bonds such as carbonyl or C=C motifs can be achieved by hydrogenation reactions. We describe here a highly chemoselective Mn(I)-based PNP pincer catalyst for the hydrosilylation of aldehydes and ketones employing polymethylhydrosiloxane (PMHS) as inexpensive hydrogen donor. Graphic abstract

Mild and Convenient Method for Reduction of Carbonyl Compounds with the NaBH4/Charcoal System in Wet THF

2006 ◽  
Vol 61 (10) ◽  
pp. 1275-1281 ◽  
Author(s):  
Davood Setamdideh ◽  
Behzad Zeynizadeh
Keyword(s):  
Convenient Method ◽  
Carbonyl Compounds ◽  
Aprotic Solvent ◽  
Reduction Reactions ◽  
Unsaturated Aldehydes ◽  
Aldehydes And Ketones

The NaBH4/C (charcoal) system reduces a variety of carbonyl compounds such as aldehydes, ketones, acyloins and α-diketones to their corresponding alcohols in high to excellent yields. Reduction reactions were carried out in wet THF at r. t. In addition, regioselective 1,2-reduction of α,β - unsaturated aldehydes and ketones was achieved perfectly with this reducing system. By decreasing the amount of aprotic solvent, all reductions took place fast and efficiently under solid-gel condition

NaBH4/NaHSO4·H2O a Heterogeneous Acidic System for a Mild and Convenient Reduction of Carbonyl Compounds under Protic Condition

2005 ◽  
Vol 60 (4) ◽  
pp. 453-457 ◽  
Author(s):  
Behzad Zeynizadeh ◽  
Tarifeh Behyar
Keyword(s):  
Carbonyl Compounds ◽  
Room Temperature ◽  
Reduction Reactions ◽  
Heterogeneous Condition ◽  
Unsaturated Aldehydes ◽  
Sodium Bisulfate ◽  
Aldehydes And Ketones ◽  
Acidic Reagent

NaBH4 in the presence of sodium bisulfate (NaHSO4·H2O), a weakly acidic reagent, efficiently reduces a variety of carbonyl compounds such as aldehydes, ketones, α,β -unsaturated aldehydes and ketones, α-diketones and acyloins to their corresponding alcohols in acetonitrile under heterogeneous condition. Reduction reactions were accomplished at room temperature or under reflux condition

scholarly journals Iridium-Catalyzed Transfer Hydrogenation of Ketones and Aldehydes Using Glucose as a Sustainable Hydrogen Donor

Catalysts ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. 503 ◽  
Author(s):  
Masato Yoshida ◽  
Ryota Hirahata ◽  
Takayoshi Inoue ◽  
Takuya Shimbayashi ◽  
Ken-ichi Fujita
Keyword(s):  
Catalytic System ◽  
Carbonyl Compounds ◽  
Hydrogen Donor ◽  
Transfer Hydrogenation ◽  
Environmentally Benign ◽  
Iridium Catalyst ◽  
Hydrogenation Reactions

A new catalytic system for transfer hydrogenation of carbonyl compounds using glucose as a hydrogen donor was developed. Various ketones and aldehydes were efficiently converted to corresponding alcohols with two equivalents of glucose in the presence of a small amount (0.1 to 1.0 mol%) of iridium catalyst that had a functional ligand. In this catalytic system, transfer hydrogenation reactions proceeded based on the cooperativity of iridium and a functional ligand. It should be noted that environmentally benign water could have been used as a solvent in the present catalytic system for the reduction of various carbonyl substrates. Furthermore, the reaction scope could be extended by using N,N-dimethylacetamide as a reaction solvent.

scholarly journals Copper(I) Chloride/Kieselguhr: A Versatile Catalyst for Oxidation of Alkyl Halides and Alkyl Tosylates to the Carbonyl Compounds

1999 ◽  
Vol 23 (7) ◽  
pp. 434-435
Author(s):  
Mohammed M. Hashemi ◽  
Yousef Ahmadi Beni
Keyword(s):  
Carbonyl Compounds ◽  
Alkyl Halides ◽  
Aldehydes And Ketones ◽  
High Yields

Copper(I) Chloride adsorbed on Kieselguhr in the presence of oxygen catalyses oxidation of alkyl halides and alkyl tosylates to the aldehydes and ketones in high yields.

A Simplified Version of the Phospha-Wittig Synthesis of P=C Double Bonds from Carbonyl Compounds

Synlett ◽  
1990 ◽  
Vol 1990 (03) ◽  
pp. 171-172 ◽  
Author(s):  
Pascal Le Floch ◽  
François Mathey
Keyword(s):  
Carbonyl Compounds ◽  
Double Bonds

scholarly journals 3-Arylaziridine-2-carboxylic Acid Derivatives and (3-Arylaziridin-2-yl)ketones: The Aziridination Approaches

2021 ◽  
Vol 22 (18) ◽  
pp. 9861
Author(s):  
Boriss Strumfs ◽  
Romans Uljanovs ◽  
Kirils Velikijs ◽  
Peteris Trapencieris ◽  
Ilze Strumfa
Keyword(s):  
Carboxylic Acid ◽  
Carbonyl Compounds ◽  
Synthetic Chemistry ◽  
Significant Progress ◽  
Current Review ◽  
Recent Advances ◽  
Year 2000

Aziridination reactions represent a powerful tool in aziridine synthesis. Significant progress has been achieved in this field in the last decades, whereas highly functionalized aziridines including 3-arylated aziridine-2-carbonyl compounds play an important role in both medical and synthetic chemistry. For the reasons listed, in the current review we have focused on the ways to obtain 3-arylated aziridines and on the recent advances (mainly since the year 2000) in the methodology of the synthesis of these compounds via aziridination.

scholarly journals Michael addition of carbonyl compounds to nitroolefins under the catalysis of new pyrrolidine-based bifunctional organocatalysts

2018 ◽  
Vol 16 (6) ◽  
pp. 924-935 ◽  
Author(s):  
A. Castán ◽  
R. Badorrey ◽  
J. A. Gálvez ◽  
P. López-Ram-de-Víu ◽  
M. D. Díaz-de-Villegas
Keyword(s):  
Michael Addition ◽  
Carbonyl Compounds ◽  
Asymmetric Michael Addition ◽  
Aldehydes And Ketones

Novel bifunctional pyrrolidine-based organocatalysts applicable for the asymmetric Michael addition of aldehydes and ketones to nitroolefins have been developed.

Thermolysis of Δ3-1,3,4-oxadiazolin-2-ones and 2-phenylimino-Δ3-1,3,4-oxadazolines derived from α,β-epoxyketones. An alternative method for the convers of α,β-epoxyketones to alkynones and alkynals

1978 ◽  
Vol 56 (3) ◽  
pp. 308-315 ◽  
Author(s):  
Gerald A. MacAlpine ◽  
John Warkentin
Keyword(s):  
Carbonyl Compounds ◽  
Polar Solvents ◽  
Parallel Decomposition ◽  
Alternative Method ◽  
Aldehydes And Ketones ◽  
Decomposition Pathway

Thermolyses in polar solvents, of Δ3-1,3,4-oxadiazolin-2-ones or 2-phenylimino-Δ3-1,3,4-oxadiazolines derived from α,β-epoxyketones, yields acetylenic carbonyl compounds. Good yields of acetylenic aldehydes and ketones are obtained for those cases in which the epoxide is ring fused. Extension to acyclic cases failed primarily due to predominance of a parallel decomposition pathway. The method complements the procedures developed by Eschenmoser and co-workers for the conversion of, α,β-epoxyketones into acetylenic carbonyl compounds.

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