The effect of maternal antidepressants on third trimester uteroplacental hemodynamics and the neonatal abstinence syndrome: a retrospective cohort study

2019 ◽  
Vol 22 (6) ◽  
pp. 791-797 ◽  
Author(s):  
Katherine McLean ◽  
Kellie E. Murphy ◽  
Ariel Dalfen ◽  
Alison K. Shea
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Neonatal Abstinence Syndrome ◽  
Abstinence Syndrome ◽  
Third Trimester

Obstetric outcomes of pregnancy complicated by urolithiasis: a retrospective cohort study

2021 ◽  
Vol 49 (1) ◽  
pp. 54-59
Author(s):  
Emily K. Clennon ◽  
Bharti Garg ◽  
Brian D. Duty ◽  
Aaron B. Caughey
Keyword(s):  
Cohort Study ◽  
Gestational Diabetes ◽  
Preterm Delivery ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Gestational Hypertension ◽  
Neonatal Abstinence Syndrome ◽  
Obstetric Outcomes ◽  
Abstinence Syndrome ◽  
Increased Risk

AbstractObjectivesEvaluate the association between urolithiasis during pregnancy and obstetric outcomes outside the context of urological intervention.MethodsWe conducted a retrospective cohort study of singleton, non-anomalous gestations delivered at 23–42 weeks in California from 2007 to 2011. Maternal outcomes (preterm delivery [early (<32 weeks) and late (<37 weeks)], preeclampsia, gestational diabetes, cesarean deliveries, urinary tract infection [UTI] at delivery, chorioamnionitis, endomyometritis, and maternal sepsis) and newborn outcomes (seizure, respiratory distress syndrome, hypoglycemia, jaundice, and neonatal abstinence syndrome [NAS]) were compared using χ2-tests and multivariable logistic regression.ResultsA total of 2,013,767 pregnancies met inclusion criteria, of which 5,734 (0.28%) were complicated by urolithiasis. Stone disease during pregnancy was associated with 30% greater odds of each early (aOR 1.30; 95% CI 1.19–1.43) and late (aOR 1.29; 95% CI 1.18–1.41) preterm delivery. Cesarean delivery, UTI at delivery, gestational hypertension, gestational diabetes, preeclampsia, and sepsis were all significantly positively associated with urolithiasis. Odds of NAS (aOR 2.11; 95% CI 1.27–3.51) and jaundice were significantly greater in the neonates of stone-forming patients (aOR 1.08; 95% CI 1.01–1.16).ConclusionsUrolithiasis during pregnancy was associated with 30% greater odds of preterm delivery and increased risk of myriad metabolic, hypertensive, and infectious disorders of gestation. Neonates born to stone-forming patients were more than twice as likely to develop neonatal abstinence syndrome but did not have significantly greater odds of complications of prematurity.

scholarly journals The prevalence of brain lesions after in utero surgery for twin-to-twin transfusion syndrome on third-trimester MRI: a retrospective cohort study

2020 ◽  
Author(s):  
Michael Aertsen ◽  
Caroline Van Tieghem De Ten Berghe ◽  
Sanne Deneckere ◽  
Isabel Couck ◽  
Luc De Catte ◽  
...  
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
In Utero ◽  
Brain Lesions ◽  
Third Trimester

scholarly journals Perinatal Outcomes of Monochorionic-Diamniotic Twin Pregnancies Uncomplicated at 28 Weeks of Gestation

2016 ◽  
Vol 7 ◽  
pp. JCM.S38895 ◽  
Author(s):  
Shunji Suzuki
Keyword(s):  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Perinatal Outcomes ◽  
Second Trimester ◽  
Perinatal Complications ◽  
Third Trimester ◽  
The Third ◽  
Perinatal Center ◽  
Twin Pregnancies

We examined the prevalence of specific perinatal complications of monochorionic-diamniotic twin pregnancies in cases without any abnormal findings until the second trimester of pregnancy. This was a retrospective cohort study performed at a tertiary perinatal center in Tokyo, Japan. There were 88 cases of uncomplicated monochorionic-diamniotic twin pregnancies at 28 weeks of gestation. In five of them (5.7%), there were serious complications associated with placental circulatory imbalance between the twins during the third trimester of pregnancy. Two cases were complicated by twin–twin transfusion syndrome, two cases were complicated by twin anemia–polycythemia sequence, and one case was complicated by acute twin–twin transfusion syndrome. In the five cases, no abnormal ultrasonographic findings or symptoms were recognized one or two weeks prior to the diagnosis. Fifty-eight cases (65.9%) were delivered at term uneventfully. Serious complications due to placental circulatory imbalance between twins occurred in about 6% of cases during the third trimester of pregnancy.

Predicting fetal growth deviation in parous women: combining the birth weight of the previous pregnancy and third trimester ultrasound scan

2015 ◽  
Vol 43 (4) ◽  
Author(s):  
Ioannis Papastefanou ◽  
Athena P. Souka ◽  
Makarios Eleftheriades ◽  
Athanasios Pilalis ◽  
Charalambos Chrelias ◽  
...  
Keyword(s):  
Cohort Study ◽  
Birth Weight ◽  
Fetal Growth ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Ultrasound Scan ◽  
Third Trimester ◽  
Previous Pregnancy ◽  
Singleton Pregnancies

AbstractTo investigate the value of the birth weight of the previous pregnancy (BWSome 1298 parous women with uncomplicated singleton pregnancies who had a third trimester ultrasound scan were considered as samples in this retrospective cohort study. Maternal and pregnancy characteristics, BWBW: BW

scholarly journals Ramifications of third trimester amniocentesis in twin pregnancies: a retrospective cohort study

2020 ◽  
Author(s):  
Avital Wertheimer ◽  
Dean Decter ◽  
Adi Borovich ◽  
Ron Bardin ◽  
Eran Hadar ◽  
...  
Keyword(s):  
Cohort Study ◽  
Gestational Age ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Tertiary Hospital ◽  
Premature Rupture Of Membranes ◽  
Third Trimester ◽  
Membrane Rupture ◽  
The Third ◽  
Twin Pregnancies

Abstract Background: To determine the association between gestational age at amniocentesis and procedure-related complications in twin gestations.Methods: A retrospective cohort study of all twin gestations that underwent amniocentesis in a tertiary hospital between 2007 and 2016. Outcomes and procedure related complications were compared between third trimester (≥24 weeks) and mid-trimester amniocentesis (16-23 weeks). Results: Compared to mid-trimester amniocentesis (n=157 (84.9%)), the third trimester group (n=28 (15.1%)) was younger (31.5 vs. 35.3 years, p<0.001) and presented with more fetal growth restriction (28% vs. 10% p=0.015). Membrane rupture within 4 weeks of amniocentesis was significantly higher in the third trimester amniocentesis group (31% vs. 1%, p<0.001). Multivariate analysis suggested gestational age at amniocentesis as an independent risk factor for premature rupture of membranes within 4 weeks of amniocentesis. Conclusions: Third trimester amniocentesis in twin pregnancies is associated with significantly higher rates of procedure related membrane rupture compared to mid-trimester amniocentesis.

scholarly journals Analysis of the results of a retrospective cohort study of the course of pregnancy, childbirth and the postpartum period in high-risk patients to identify factors of unfavorable outcomes and build a predictive model of fetal loss

2021 ◽  
Vol 2 ◽  
pp. 47-52
Author(s):  
V.I.  Оshovskyy
Keyword(s):  
Heart Rate ◽  
Cohort Study ◽  
Retrospective Cohort Study ◽  
Fetal Heart Rate ◽  
Retrospective Cohort ◽  
Fetal Heart ◽  
Perinatal Loss ◽  
Third Trimester ◽  
The Third ◽  
Fetal Heart Rate Variability

Prenatal prognosis is an important part of obstetric care, which aims to reduce fetal and neonatal losses. A differentiated approach to the management of different risk groups allows you to optimize existing approaches.The objective: to identify antenatal factors that correlate with perinatal losses, by conducting a retrospective cohort study of women at high perinatal risk, to build a multifactorial prognostic model of adverse pregnancy outcomes.Materials and methods. A retrospective cohort study was conducted from 2014 to 2016 on the basis of the medical center LLC «Uniclinic», Medical Genetics Center «Genome», Clinic of Reproductive Genetics «Victoria», Kyiv City Maternity Hospital №2. 2154 medical cards of pregnant women from the group of high perinatal risk were selected and analyzed. Of these, 782 pregnant women were included in the final protocol after verification of compliance with the criteria.Results. Cesarean delivery occurred in 115 cases (14.7%). In 50 cases (6.4%) the caesarean section was performed in a planned manner, in 65 (8.3%) – in an emergency. In 39 (5%) cases, the indication for surgical delivery was acute fetal distress. Antenatal fetal death occurred in 11 (1.4%) cases: one case in terms of <34 weeks and <37 weeks of gestation, the remaining 9 cases – in terms of> 37 weeks. Intranatal death of two fetuses (0.3%) was due to acute asphyxia on the background of placental insufficiency. In the early neonatal period, 14 (1.8%) newborns died. Hospitalization of the newborn to the intensive care unit for the first 7 days was registered in 64 (8.2%) cases.The need for mechanical ventilation was stated in 3.96% (31/782) of newborns. The method of construction and analysis of multifactor models of logistic regression was used in the analysis of the relationship between the risk of perinatal losses (antenatal death, intranatal death, early neonatal death) and factor characteristics.Conclusion. Signs associated with the risk of perinatal loss: the presence of chronic hypertension, preeclampsia in previous pregnancies, type of fertilization (natural or artificial), the concentration of PAPP-A (MoM), the concentration of free β-HCG (MoM) in the second trimester, average PI in the uterine arteries in 28–30 weeks of pregnancy, PI in the middle cerebral arteries in 28–30 weeks of pregnancy, episodes of low fetal heart rate variability in the third trimester of pregnancy, episodes of high fetal heart rate variability in the third trimester of pregnancy. The model, built on selected features, allows with a sensitivity of 73.1% (95% CI: 52.2% – 88.4%) and a specificity of 72.7% (95% CI: 69.3% – 75.9%) to predict risk perinatal loss.

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