Tic disorders in children and adolescents: does the clinical presentation differ in males and females? A report by the EMTICS group

2021 ◽  
Author(s):  
Blanca Garcia-Delgar ◽  
◽  
Mateu Servera ◽  
Barbara J. Coffey ◽  
Luisa Lázaro ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Clinical Presentation ◽  
Tic Disorders ◽  
Males And Females

Lifetime Prevalence, Predictors and Comorbidities of Tic Disorders: A Population—Based Survey of Children and Adolescents in Iran

2021 ◽  
Author(s):  
Mohammad Reza Mohammadi ◽  
Rahim Badrfam ◽  
Ali Khaleghi ◽  
Nastaran Ahmadi ◽  
Zahra Hooshyari ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Population Based ◽  
Tic Disorders ◽  
Lifetime Prevalence ◽  
Population Based Survey

scholarly journals Association between serum uric acid and triglycerides in Chinese children and adolescents with short stature

2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Yuntian Chu ◽  
Qianqian Zhao ◽  
Mei Zhang ◽  
Bo Ban ◽  
Hongbing Tao
Keyword(s):  
Uric Acid ◽  
Standard Deviation ◽  
Children And Adolescents ◽  
Linear Relationship ◽  
Short Stature ◽  
Serum Uric Acid ◽  
Standard Deviation Score ◽  
Short Children ◽  
Non Linear ◽  
Males And Females

Abstract Background Elevated triglyceride (TG) levels are a biomarker for cardiovascular disease (CVD) risk. The correlation between serum uric acid (SUA) and TG concentrations in adults or obese children is well established. However, studies on SUA and TG in children with short stature are limited. Aim To determine the relationship between SUA and TG levels in short children and adolescents. Method This was a cross-sectional evaluation of a cohort of 1095 patients with short stature (720 males and 375 females). The related clinical characteristics, including anthropometric and biochemical parameters, were determined. Results Smooth curve fitting, adjusted for potential confounders was performed, which indicated the existence of a non-linear relationship between these measures. Piecewise multivariate linear analysis revealed a significant positive relationship between SUA and TG at SUA concentrations over 7 mg/dL (β = 0.13, 95% CI: 0.05–0.22, P = 0.002) but no significant correlation at lower SUA levels (β = 0.01, 95% CI: 0.01–0.04, P = 0.799). Furthermore, a stratified analysis was performed to appraise changes in this relationship for different sexes and standard deviation levels of body mass index (BMI). The non-linear relationship remained consistent in males and females with BMI standard deviation scores (BMI SDS) ≥ 0, with inflection points of 6.71 mg/dL and 3.93 mg/dL, respectively. Within these two groups, SUA and TG levels showed a positive association when SUA levels were higher than the inflection point (β = 0.21, 95% CI: 0.11–0.31, P < 0.001 for males and β = 0.1, 95% CI: 0.03–0.17, P = 0.005 for females). However, a specific relationship was not observed at lower SUA levels. No significant relationships were found between SUA and TG levels in males and females with BMI SDS < 0. Conclusion The present study identified the non-linear association of SUA and TG levels with short children and adolescents. This relationship was based on BMI status. This finding suggests that health status should be considered for short stature children with high SUA levels, especially in children with a high BMI standard deviation score.

scholarly journals The prevalence of tic disorders in children and adolescents in Brazil

2014 ◽  
Vol 72 (12) ◽  
pp. 942-948 ◽  
Author(s):  
Helvio L. Alves ◽  
Elizabeth M. A. B. Quagliato
Keyword(s):  
Special Education ◽  
Children And Adolescents ◽  
Tourette Syndrome ◽  
Special Education Students ◽  
Tic Disorders ◽  
Education Students ◽  
Tic Disorder ◽  
Item Questionnaire ◽  
Chronic Tic Disorder

Tourette syndrome (TS) and tic disorders represent events of familiar magnitude characterized by involuntary movements and/or vocalization. To determine the prevalence of TS/tic disorders we studied a sample of 762 subjects (388 M, 374 F), between 1992 and 1997, age 6 to 43 years old, taken out of a population of 10,155 subjects (4,918 M, 5,237 F; age: 3-56 years old). A structured 4-item questionnaire, direct interview (multistaged), >1 yr follow-up, were used. 9,565 subjects (4,614 M, 4,951 F) sent back the questionnaires, 3,354 of these (1,671 M, 1,683 F) with positive answers to tics. 42 subjects (31 M, 11 F, age: 7-21 years old, mean: 11 years old) met the DSM-III-R criteria. The total minimal prevalence of TS is 0.43%, with a 3:1 ratio male/female. The minimal prevalence of chronic tic disorder is 2.27%. The total minimal prevalence for tic disorders at all is 2.91%. No special education students participation.

scholarly journals Consequences of COVID-19 Confinement on Anxiety, Sleep and Executive Functions of Children and Adolescents in Spain

2021 ◽  
Vol 12 ◽  
Author(s):  
Rocío Lavigne-Cerván ◽  
Borja Costa-López ◽  
Rocío Juárez-Ruiz de Mier ◽  
Marta Real-Fernández ◽  
Marta Sánchez-Muñoz de León ◽  
...  
Keyword(s):  
Executive Functioning ◽  
Executive Functions ◽  
Children And Adolescents ◽  
State Anxiety ◽  
Sleep Disturbances ◽  
Online Questionnaire ◽  
Present Sample ◽  
Relevant Effect ◽  
Males And Females ◽  
Positive Correlations

Children and adolescents are not indifferent to the dramatic impact of the COVID-19 pandemic, and the need to be forced to live in confinement. The change in life to which they have been abruptly subjected forces us to understand the state of their mental health in order to adequately address both their present and future needs. The present study was carried out with the intention of studying the consequences of confinement on anxiety, sleep routines and executive functioning of 1,028 children and adolescents, aged from 6 to 18 years, residing in Spain to; assess if there are differences regarding these consequences in terms of sex and age; how anxiety affects executive functioning in males and females; and to examine the possible correlations between the measured variables. For this purpose, an online questionnaire containing five sections was designed: the first section gathers information on sociodemographic and health data, while the following sections gather information from different standardized scales which measure anxiety, sleep and executive functions, whose items were adapted in order to be completed by parents, and/or legal guardians. The statistical analyzes carried out highlights significant differences in executive functioning between males and females. In turn, in regards to age, greater difficulties were detected in anxiety in the 9 to 12 age group and greater sleep disturbances between 13 and 18 year olds. On the other hand, significant differences were found in intra-sexual executive functioning depending on whether they presented greater or lesser anxiety, with executive functioning being more tendentiously maladjusted in males than in females, revealing a significantly relevant effect size (p = 0.001; ω2 = 0.27 BRIEF-2; ω2 = 0.19 BDEFS-CA; 95%). Positive correlations are obtained between state anxiety and sleep and executive functioning alterations. Finally, through Path Analysis, it is verified that state anxiety is the variable with the greatest weight within the model that would explain the alteration in the executive functioning of the present sample.

New Standards for the Bruce Treadmill Protocol in Children and Adolescents

2001 ◽  
Vol 13 (4) ◽  
pp. 392-401 ◽  
Author(s):  
Hans U. Wessel ◽  
Janette F. Strasburger ◽  
Brett M. Mitchell
Keyword(s):  
Heart Rate ◽  
Heart Disease ◽  
Body Size ◽  
Children And Adolescents ◽  
Age Groups ◽  
Exercise Heart Rate ◽  
Regression Equations ◽  
Asymptomatic Children ◽  
Acquired Heart Disease ◽  
Males And Females

We have developed normal standards for the Bruce exercise (EX) protocol since a review of 875 studies in patients with congenital or acquired heart disease showed that only 5.1% achieved the predicted 50th percentile for EX time of the standards reported by Cumming, Everatt, and Hastman (Am. J Cardiol 41:69, 1978). Our data are based on 160 males and 103 females, age 4–18 years who met the following criteria: trivial or no heart disease, maximal effort, maximal EX heart rate (HR) > 180 beats/min, and normal resting and EX ECG without arrhythmia. The ECG was monitored continuously and HR computed from the ECG and the end of each minute of EX. Comparison with the predicted data of Cumming et al. for each age group by stage showed essentially identical submaximal EX heart rates but slightly lower maximal HR (–2%), which averaged 197 beats per minute in males and females. EX times were on average 15% lower than the predicted 50th percentile for most age groups in males and females. We developed regression equations, which predict exercise time from age and body size or age, body size and 2nd stage exercise heart rate. They better reflect the capabilities of untrained, asymptomatic children and adolescents seen in our laboratory in the 1990s than the Canadian data of 1978.

Obsessive–compulsive disorder and tics in children and adolescents

2012 ◽  
pp. 1680-1693
Author(s):  
Martine F. Flament ◽  
Philippe Robaey
Keyword(s):  
Children And Adolescents ◽  
Treatment Strategies ◽  
Tic Disorders ◽  
Older Individuals ◽  
Obsessive Compulsive ◽  
Pharmacological Agents ◽  
Assessment And Treatment ◽  
Ongoing Relationship

Paediatric OCD is the disorder, in child psychiatry, whose clinical picture most closely resembles its adult counterpart. Despite a relative diversity, the symptom pool is remarkably finite, and very similar to that seen in older individuals. Prevalence, comorbidity, and response to behavioural and drug treatment also appear similar across the lifespan. For tic disorders, there is continuity between child and adult presentations, but the disease is much more prone to resolve spontaneously, or to be less disruptive in adulthood. Both OCD and tics occur more often in males than in females, and are likely to be linked to an array of neurobiological abnormalities, many of which remain to be understood. Invaluable benefits can now be obtained from available behavioural and pharmacological treatments, but complete remission remains uncertain and long-term management may be required. Thus, the treatment of OCD and tics in children and adolescents remains a clinical challenge. It requires careful assessment of the targeted symptoms and, in many cases, comorbidity; attention to the quality of the child's functioning at home and with peers; use of specific CBT interventions, which are not readily available (or accessible) in all communities; patience and caution in the choice and adjustment of medication; and vigilance in watching potential side effects. Given the possible chronicity of OCD and/or tic disorders, and their changing patterns in severity and impact over the childhood and adolescent years, optimal treatment generally requires a long-term ongoing relationship with the child and family. Current conceptualizations of OCD and tic disorders have been shaped by advances in systems neuroscience and functional in vivo neuroimaging. Continued success in these areas should lead to the targetting of specific brain circuits for more intensive research. This should include testing novel pharmacological agents, tracking treatment response using neuroimaging techniques, and possibly investigating circuit-based therapies using deep-brain stimulation for refractory cases. The identification of the PANDAS subgroup of patients, with an abrupt onset and dramatic exacerbations, certainly brings new insights into the pathophysiology of OCD and tic disorders, and may lead to new assessment and treatment strategies. The increasing evidence for susceptibility genes in OCD and tic disorders will also doubtless point to new therapeutic directions. Furthermore, it is likely that many of the empirical findings used in research on paediatric OCD and tic disorders will be relevant to a better understanding of both normal development, and other disorders of childhood onset.

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