Quantification of bone marrow edema in rheumatoid arthritis by using high-speed T2-corrected multiecho acquisition of 1H magnetic resonance spectroscopy: a feasibility study

2021 ◽  
Author(s):  
Wenzhao Yuan ◽  
Yiwu Lei ◽  
Cheng Tang ◽  
Fang Qin ◽  
Jing Wen ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Feasibility Study ◽  
High Speed ◽  
Bone Marrow Edema ◽  
Resonance Spectroscopy ◽  
1H Magnetic Resonance Spectroscopy ◽  
Marrow Edema

Detecting Bone Marrow Edema With Magnetic Resonance Spectroscopy: A Brief Report

2020 ◽  
Vol 16 (8) ◽  
pp. e129-e132
Author(s):  
Arya Minaie ◽  
Katherine Woolley ◽  
Ryan Smith ◽  
Olohirere Ezomo ◽  
Richard Feinn ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Bone Marrow Edema ◽  
Resonance Spectroscopy ◽  
Marrow Edema

scholarly journals Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis

2007 ◽  
Vol 56 (4) ◽  
pp. 1118-1124 ◽  
Author(s):  
Esther Jimenez-Boj ◽  
Iris Nöbauer-Huhmann ◽  
Beatrice Hanslik-Schnabel ◽  
Ronald Dorotka ◽  
Axel-Hugo Wanivenhaus ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Bone Marrow Edema ◽  
Resonance Imaging ◽  
Bone Erosions ◽  
Marrow Edema

Bone Marrow Edema Is the Most Specific Finding for Rheumatoid Arthritis (RA) on Noncontrast Magnetic Resonance Imaging of the Hands and Wrists: A Comparison of Patients with RA and Healthy Controls

2009 ◽  
Vol 37 (2) ◽  
pp. 265-274 ◽  
Author(s):  
EWA OLECH ◽  
JOHN V. CRUES ◽  
DAVID E. YOCUM ◽  
JOAN T. MERRILL
Keyword(s):  
Rheumatoid Arthritis ◽  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Healthy Subjects ◽  
Bone Marrow Edema ◽  
Intraclass Correlation ◽  
Resonance Imaging ◽  
Bone Edema ◽  
Marrow Edema

Objective. To evaluate the sensitivity and specificity of magnetic resonance imaging (MRI) in detecting erosions, bone edema, and synovitis in the metacarpophalangeal and wrist joints for rheumatoid arthritis (RA).Methods. MRI scans of bilateral hands and wrists of 40 healthy subjects and 40 RA patients were performed using 0.2 T extremity-MRI and read blindly using a modified RA MRI (RAMRIS) system (no contrast injection, imaging in 1 plane only). To determine interreader reliability, images of 10 randomly selected subjects were read independently by a musculoskeletal radiologist.Results. A total of 3360 bones were evaluated. Patients with RA had significantly more erosions as well as higher scores for bone edema and synovitis than healthy subjects. Age had a significant effect on the number of erosions in both groups. However, when disease duration was factored in, age became insignificant in RA patients. Erosion number correlated with positive rheumatoid factor and higher C-reactive protein values. The intraclass correlation coefficient between the 2 readers was 0.76 for individual joints and 0.88 for total scores. When having a single erosion was used as a positive test for RA, the sensitivity of this test was 90%, but the specificity was only 35%. Presence of bone edema provided 65% sensitivity and 82.5% specificity. Eliminating the lunate from scoring for bone edema increased the specificity to 87.5% while decreasing the sensitivity to 62.5%.Conclusion. While MRI is a highly sensitive tool for identifying and tracking the progression of erosions, erosions detected by MRI with measures commonly used in a rheumatologist’s office (no contrast, imaging in 1 plane) provide low specificity for RA. Bone marrow edema is the most specific MRI lesion for RA in this setting.

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