Intra-articular Treatment with Hyaluronic Acid. Comparative Study of Hyalgan and Adant

2000 ◽  
Vol 19 (3) ◽  
pp. 204-206 ◽  
Author(s):  
J. A. Román ◽  
J. Chismol ◽  
M. Morales ◽  
J. L. Donderis
Keyword(s):  
Hyaluronic Acid ◽  
Comparative Study

A comparative study of dissolving hyaluronic acid microneedles with trehalose and poly(vinyl pyrrolidone) for efficient peptide drug delivery

2018 ◽  
Vol 6 (10) ◽  
pp. 2566-2570 ◽  
Author(s):  
Hong Kee Kim ◽  
Soo Hyeon Lee ◽  
Boo Yong Lee ◽  
Sung Jin Kim ◽  
Chang Yub Sung ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Hyaluronic Acid ◽  
Comparative Study ◽  
Vinyl Pyrrolidone ◽  
Peptide Drug ◽  
Pharmacokinetic Properties ◽  
Poly Vinyl Pyrrolidone

We studied the role of the additives trehalose and poly(vinyl pyrrolidone) in the physical and pharmacokinetic properties of peptide drug incorporated microneedles.

scholarly journals THE RELATIONSHIP BETWEEN SPREADING FACTOR AND HYALURONIDASE

1941 ◽  
Vol 73 (1) ◽  
pp. 109-123 ◽  
Author(s):  
Gladys L. Hobby ◽  
Martin H. Dawson ◽  
Karl Meyer ◽  
Eleanor Chaffee
Keyword(s):  
Hyaluronic Acid ◽  
Comparative Study ◽  
Chemical Reaction ◽  
Spreading Factor ◽  
Hyaluronidase Activity ◽  
Comparable Effect ◽  
Simple Chemical ◽  
The Relationship ◽  
Homologous Enzyme

A comparative study of spreading factor and hyaluronidase in preparations from various sources revealed the following points of similarity and dissimilarity in the two reactions. 1. Similarities: (a) All preparations containing hyaluronidase also produced spreading. (b) Heating at 65° and 100°C. for 30 minutes produced a comparable effect on both reactions. (c) The demonstration of the presence of hyaluronic acid in skin offers a plausible explanation for the mechanism of spreading on the basis of hyaluronidase activity. 2. Dissimilarities: (a) No parallelism was observed in the degree of activity of spreading factor and hyaluronidase in the same preparations. (b) All preparations which produced spreading did not contain hyaluronidase. (c) Antisera to hyaluronidase preparations specifically and completely inhibited the activity of the homologous enzyme but did not inhibit the spreading factor in the same preparations. The significance of the similarities and dissimilarities between the two reactions is discussed. It is concluded that while hyaluronidase may play a rôle in the spreading reaction the phenomenon is a complex one and cannot be explained on the basis of a simple chemical reaction.

scholarly journals Correction of volumetric aging of hands: comparative study between calcium hydroxyapatite and hyaluronic acid

2017 ◽  
Vol 9 (4) ◽  
Author(s):  
Guilherme Bueno de Oliveira ◽  
Natália Cristina Rossi Bueno de Oliveira ◽  
Bárbara Maria Tarraf Moreira ◽  
Marcela Ferraz Awada ◽  
Vitória Carneiro Assunção Zerati
Keyword(s):  
Hyaluronic Acid ◽  
Comparative Study ◽  
Calcium Hydroxyapatite
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