scholarly journals Disagreement between the results from three commercial tests for the detection of Borrelia-specific serum antibodies in the Netherlands associated with antibiotic treatment for Lyme borreliosis: a retrospective study

2017 ◽  
Vol 36 (11) ◽  
pp. 2137-2146 ◽  
Author(s):  
T. van Gorkom ◽  
K. Kremer ◽  
W. Voet ◽  
D. W. Notermans ◽  
B. J. M. Vlaminckx ◽  
...  
Keyword(s):  
Retrospective Study ◽  
The Netherlands ◽  
Antibiotic Treatment ◽  
Lyme Borreliosis ◽  
Serum Antibodies ◽  
Specific Serum

scholarly journals The prevalence of seasonal affective disorder in the netherlands: a prospective and retrospective study of seasonal mood variation in the general population

1999 ◽  
Vol 45 (8) ◽  
pp. 1013-1022 ◽  
Author(s):  
Peter Paul A Mersch ◽  
Hermine M Middendorp ◽  
Antoinette L Bouhuys ◽  
Domien G.M Beersma ◽  
Rutger H van den Hoofdakker
Keyword(s):  
Retrospective Study ◽  
General Population ◽  
The Netherlands ◽  
Affective Disorder ◽  
Seasonal Affective Disorder ◽  
Mood Variation

scholarly journals Immune Responses to Defined Antigens of Mycobacterium bovis in Cattle Experimentally Infected with Mycobacterium kansasii

2006 ◽  
Vol 13 (6) ◽  
pp. 611-619 ◽  
Author(s):  
W. R. Waters ◽  
M. V. Palmer ◽  
T. C. Thacker ◽  
J. B. Payeur ◽  
N. B. Harris ◽  
...  
Keyword(s):  
Mycobacterium Bovis ◽  
Bovine Tuberculosis ◽  
Nontuberculous Mycobacteria ◽  
Gamma Interferon ◽  
Delayed Type Hypersensitivity ◽  
Enzyme Linked Immunosorbent Assay ◽  
Serum Antibodies ◽  
Specific Serum ◽  
Specific Proteins

ABSTRACT Cross-reactive responses elicited by exposure to nontuberculous mycobacteria often confound the interpretation of antemortem tests for Mycobacterium bovis infection of cattle. The use of specific proteins (e.g., ESAT-6, CFP-10, and MPB83), however, generally enhances the specificity of bovine tuberculosis tests. While genes for these proteins are absent from many nontuberculous mycobacteria, they are present in M. kansasii. Instillation of M. kansasii into the tonsillar crypts of calves elicited delayed-type hypersensitivity and in vitro gamma interferon and nitrite concentration responses of leukocytes to M. avium and M. bovis purified protein derivatives (PPDs). While the responses of M. kansasii-inoculated calves to M. avium and M. bovis PPDs were approximately equivalent, the responses of M. bovis-inoculated calves to M. bovis PPD exceeded their respective responses to M. avium PPD. The gamma interferon and nitrite responses of M. kansasii-inoculated calves to recombinant ESAT-6-CFP-10 (rESAT-6-CFP-10) exceeded corresponding responses of noninoculated calves as early as 15 and 30 days after inoculation, respectively, and persisted throughout the study. The gamma interferon and nitrite responses of M. bovis-inoculated calves to rESAT-6-CFP-10 exceeded the corresponding responses of M. kansasii-inoculated calves beginning 30 days after inoculation. By using a lipoarabinomannan-based enzyme-linked immunosorbent assay, specific serum antibodies were detected as early as 50 days after challenge with M. kansasii. By a multiantigen print immunoassay and immunoblotting, serum antibodies to MPB83, but not ESAT-6 or CFP-10, were detected in M. kansasii-inoculated calves; however, responses to MPB83 were notably weaker than those elicited by M. bovis infection. These findings indicate that M. kansasii infection of calves elicits specific responses that may confound the interpretation of bovine tuberculosis tests.

scholarly journals Specificity of serum neutralizing antibodies induced by transient immune suppression of inapparent carrier ponies infected with a neutralization-resistant equine infectious anemia virus envelope strain

2005 ◽  
Vol 86 (1) ◽  
pp. 139-149 ◽  
Author(s):  
Laryssa Howe ◽  
Jodi K. Craigo ◽  
Charles J. Issel ◽  
Ronald C. Montelaro
Keyword(s):  
Immune Suppression ◽  
Neutralizing Antibodies ◽  
Equine Infectious Anemia Virus ◽  
Antibody Responses ◽  
Serum Antibodies ◽  
Virus Envelope ◽  
Specific Serum ◽  
Surface Envelope ◽  
Equine Infectious Anemia ◽  
Anemia Virus

It has been previously reported that transient corticosteroid immune suppression of ponies experimentally infected with a highly neutralization resistant envelope variant of equine infectious anemia virus (EIAV), designated EIAVΔPND, resulted in the appearance of type-specific serum antibodies to the infecting EIAVΔPND virus. The current study was designed to determine if this induction of serum neutralizing antibodies was associated with changes in the specificity of envelope determinants targeted by serum antibodies or caused by changes in the nature of the antibodies targeted to previously defined surface envelope gp90 V3 and V4 neutralization determinants. To address this question, the envelope determinants of neutralization by post-immune suppression serum were mapped. The results demonstrated that the neutralization sensitivity to post-immune suppression serum antibodies mapped specifically to the surface envelope gp90 V3 and V4 domains, individually or in combination. Thus, these data indicate that the development of serum neutralizing antibodies to the resistant EIAVΔPND was due to an enhancement of host antibody responses caused by transient immune suppression and the associated increase in virus replication.

scholarly journals Myopia progression from wearing first glasses to adult age: the DREAM Study

2021 ◽  
pp. bjophthalmol-2020-316234
Author(s):  
Jan Roelof Polling ◽  
Caroline Klaver ◽  
Jan Willem Tideman
Keyword(s):  
Retrospective Study ◽  
The Netherlands ◽  
Refractive Error ◽  
High Myopia ◽  
Prognostic Indicator ◽  
Treatment Intensity ◽  
Spherical Equivalent ◽  
Inclusion Criteria ◽  
Myopia Progression ◽  
Adult Age

PurposeData on myopia progression during its entire course are scarce. The aim of this study is to investigate myopia progression in Europeans as a function of age and degree of myopia from first prescription to final refractive error.MethodsThe Drentse Refractive Error and Myopia Study assessed data from a branch of opticians in the Netherlands from 1985 onwards in a retrospective study. First pair of glasses prescribed was defined as a spherical equivalent of refraction (SER) ≤−0.5 D to ≥−3.0 D. Subjects with prescriptions at an interval of at least 1 year were included in the analysis.ResultsA total of 2555 persons (57.3% female) met the inclusion criteria. Those with first prescription before the age of 10 years showed the strongest progression (−0.50 D; IQR: −0.75 to −0.19) and a significantly (p<0.001) more negative median final SER (−4.48 D; IQR: −5.37 to −3.42). All children who developed SER ≤−3 D at 10 years were highly myopic (SER ≤−6D) as adults, children who had SER between −1.5 D and −3 D at 10 years had 46.0% risk of high myopia, and children with SER between −0.5 D and −1.5 D had 32.6% risk of high myopia. Myopia progression diminished with age; all refractive categories stabilised after age 15 years except for SER ≤−5 D who progressed up to −0.25 D annually until age 21 years.ConclusionOur trajectories of the natural course of myopia progression may serve as a guide for myopia management in European children. SER at 10 years is an important prognostic indicator and will help determine treatment intensity.

scholarly journals Decrease in tick bite consultations and stabilization of early Lyme borreliosis in the Netherlands in 2014 after 15 years of continuous increase

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Agnetha Hofhuis ◽  
Sita Bennema ◽  
Margriet Harms ◽  
Arnold J. H. van Vliet ◽  
Willem Takken ◽  
...  
Keyword(s):  
The Netherlands ◽  
Lyme Borreliosis ◽  
Tick Bite ◽  
Continuous Increase

Sa1994 Long-Term Outcome of Children Born to IBD Mothers Preliminary Result From a Multicenter Retrospective Study in the Netherlands

2015 ◽  
Vol 148 (4) ◽  
pp. S-378 ◽  
Author(s):  
Shannon L. Kanis ◽  
Alison de Lima ◽  
Zuzana Zelinkova ◽  
Gerard Dijkstra ◽  
Rachel West ◽  
...  
Keyword(s):  
Retrospective Study ◽  
The Netherlands ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals Treatment of epistaxis without the use of nasal packing, a patient study

2011 ◽  
Vol 49 (5) ◽  
pp. 600-604
Author(s):  
Esther Vis ◽  
Herbert van den Berge
Keyword(s):  
Retrospective Study ◽  
The Netherlands ◽  
Treatment Modality ◽  
Training Programs ◽  
Cost Effective ◽  
Nasal Packing ◽  
Recurrent Bleeding ◽  
Bleeding Site ◽  
Recurrence Rates ◽  
Patient Study

We questioned how many patients with epistaxis can be treated by cautery without the use of nasal packing, as cautery is more effective and efficient. To investigate this, we performed a retrospective study of a cohort of 418 patients with epistaxis who presented to one ENT consultant at the ENT department of Medisch Centrum Leeuwarden (the Netherlands) between 1997 and 2007. Main outcomes were the treatment modality (cautery and/or nasal packing), recurrence of epistaxis and need for hospitalization. In 98% of all patients the bleeding site could be found and treated by cautery. The incidence of recurrent bleeding was 6%. Two percent of all patients had to be admitted to the hospital. This is considerably lower compared with recurrence rates and hospitalization after treatment by nasal packing known from the literature. Therefore we concluded that nearly all patients can be effectively treated by cautery with a low recurrence rate. In addition, this method of treatment is very cost effective. Because cautery requires skill and appropriate facilities, we recommend special attention for this in ENT training programs.

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