Risk factors of ceftriaxone-associated biliary pseudolithiasis in adults: influence of renal dysfunction

THE AIM. Investigation of cardiovascular diseases (CVD) risk factors prevalence in men under 60 years old with myocardial infarction (MI) and renal dysfunction depending on a year season for enhanced prevention and treatment management of aforementioned target population.PATIENTS AND METHODS. In-patient treatment results analyses of 412 men in total under 60 y.o. with MI for the period of 2000-2015 indicated that within primary 48 hours from the MI onset 61 patients were having 30-59 mL/min/1,73 m2 estimated glomerular filtration rate (CKD-EPI 2009, modification 2011) and 351 patients were having more than 60 mL/min/1,73 m2 respectively. Collection of supplemental information about MI promotive conditions and disease triggers was done with their manifestation rate comparison in groups of patients with renal dysfunction (RD) and normal CKDEPI. Seasonal differences evaluation was performed with separation of events by climatic time intervals based on mean daily air temperature changes in St. Petersburg, Russia.RESULTS. RD was observed in 14.8% of the examined cases. The frequency of its detection prevailed in the spring and winter (22% each) seasons. Arterial hypertension (AH), mild obesity, hypertensive crisis events, frequent colds occurrences were noted to be detected more frequently in patients with the RD. Moderate obesity along with Ischemic Heart Disease (IHD) manifestations depending from a year season were noted less frequently. In first hours from a MI onset, RD patients demonstrated expressed dyslipidemia evidences due to hypertriglyceridemia and elevated levels of very low density lipoproteins (VLDL).CONCLUSIONS. AH was noted to be the main cause of DP in men under 60 years old in their initial hours from the IM onset. Its presence in combination with frequent colds predisposition, regardless of diabetes and obesity presence in spring and winter attributes RD development risk in MI acute period. Dyslipidemia is indicative for this type of patients, and that brings the need to assess triglyceride and VLDL blood levels.

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Cardiovascular determinants of renal dysfunction among children and adolescents in South West Nigeria

Nigerian Journal of Paediatrics ◽

10.4314/njp.v47i2.3 ◽

2020 ◽

Vol 47 (2) ◽

pp. 68-73

Author(s):

A.A. Akinbodewa ◽

O.A. Adejumo ◽

A. Ogunleye ◽

T.T. Oluwafemi ◽

O.A. Lamidi

Keyword(s):

Risk Factors ◽

Cardiovascular Risk ◽

Children And Adolescents ◽

Cardiovascular Risk Factors ◽

Renal Dysfunction ◽

Body Mass ◽

Cross Sectional Study ◽

P Value ◽

Chi Square ◽

Cross Sectional

Background: New evidences reveal significant association of cardiovascular risk factors to development of chronic kidney disease among children and adolescents but there is paucity of data from Africa. Objectives: We examined the association of cardiovascular risk factors to renal dysfunction among Nigerian pediatric subjects. Materials and method: This was a prospective, cross-sectional study of pediatrics aged 2 to 17 years. Blood pressure, body mass index, serum lipids and creatinine were determined. Their glomerular filtration rate was calculated using the revised Schwartz equation. Data was analyzed with SPSS 20. Test of association was by Chi square at P <0.05. Results: We studied 114 children and adolescents. There were 55 (48.2%) males and 59 (51.8%) females with mean age of 8.99±4.26 years. There were 68 (53.5%) children and 53 adolescents (46.5%). Four (3.5%) subjects had proteinuria ≥1+. Renal dysfunction (eGFR <60ml/ min/1.73m2) was found among 9 (7.9%) participants. Renal dysfunction was higher among children than adolescents (13.1% v 1.9%) (p = 0.027). The presence and clustering of risk factors were higher among subjects with renal dysfunction (p value 0.466, 95% CI 0.19-28.3). Low HDL-c (44.4%), prehypertension(22.2%) and overweight (22.2%) were the most prevalent risk factors among those with renal dysfunction. Only age demonstrated relationship to renal dysfunction in terms of mean difference (p value 0.007, 95% CI, 1.125-6.818). Conclusions: The prevalence and clustering of cardiovascular risk factors is higher among children with renal dysfunction. Age showed association to renal dysfunction. Dyslipidemia and high body mass have propensity to influence the development of pediatric CKD. Keywords: Cardiovascular risk factors, renal dysfunction, association, pediatrics, Nigeria, Africa.

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Incidence, risk factors and outcome of renal dysfunction after coronary surgery in patients with preoperative normal renal function

European Journal of Anaesthesiology ◽

10.1097/00003643-200706001-00141 ◽

2007 ◽

Vol 24 (Supplement 39) ◽

pp. 39

Author(s):

A. Flo ◽

A. Escudero ◽

M. Sariñena ◽

E. Massó ◽

E. Moret

Keyword(s):

Risk Factors ◽

Renal Function ◽

Renal Dysfunction ◽

Normal Renal Function ◽

Coronary Surgery ◽

Incidence Risk

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Abstract 14610: Renal Dysfunction in Adults With Congenital Heart Disease in Vietnam

Circulation ◽

10.1161/circ.142.suppl_3.14610 ◽

2020 ◽

Vol 142 (Suppl_3) ◽

Author(s):

Ngoc Thanh Kim ◽

Thanh Tung Le ◽

Doan Loi Do ◽

Thanh Huong Truong

Keyword(s):

Risk Factors ◽

Heart Failure ◽

Atrial Fibrillation ◽

Congenital Heart Disease ◽

Heart Disease ◽

Pulmonary Arterial Hypertension ◽

Arterial Hypertension ◽

Renal Dysfunction ◽

Congenital Heart ◽

Pulmonary Arterial

Introduction: In Vietnam, knowledge about renal function in adults with congenital heart disease (CHD) is limited. Hypothesis: This study aims to estimate incidence of renal dysfunction in adults with congenital heart disease and risk factors. Methods: This is a cross-sectional study, including 365 CHD patients more than 16 years old. We collected clinical and para-clinical information, estimated glomerular filtration rate (GFR) and calculated the odds ratio (OR) for reduced GFR. Results: Totally, 52.8% patients had GFR < 90 ml/phút/1.73 m 2 . Logistic regression had confirmed the OR for GFR < 90 ml/phút/1.73 m 2 in the group > 60-years-old, the group with atrial fibrillation, the group with heart failure (based on NT-proBNP > 125 pmol/L), and the group with pulmonary arterial hypertension (based on pulmonary artery systolic pressure > 50 mmHg by echocardiography) were 6.46 (95% CI: 1.37 - 30.41), 7.58 (95% CI: 1.66 - 34.56), 2.98 (95% CI: 1.49 - 5.98) and 1.84 (95% CI: 1.02 - 3.33), respectively. Conclusions: Renal dysfunction is common in adults with CHD. Age > 60 years-old, atrial fibrillation, heart failure, and pulmonary arterial hypertension were risk factors for renal dysfunction in adults with CHD.

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