The cys-loop ligand-gated ion channel gene family of Brugia malayi and Trichinella spiralis: a comparison with Caenorhabditis elegans

2007 ◽  
Vol 7 (4) ◽  
pp. 219-226 ◽  
Author(s):  
Sally M. Williamson ◽  
Thomas K. Walsh ◽  
Adrian J. Wolstenholme
Keyword(s):  
Caenorhabditis Elegans ◽  
Ion Channel ◽  
Gene Family ◽  
Trichinella Spiralis ◽  
Brugia Malayi ◽  
Channel Gene ◽  
Ion Channel Gene

scholarly journals Ion Channel Gene Expression in Lung Adenocarcinoma: Potential Role in Prognosis and Diagnosis

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e86569 ◽  
Author(s):  
Jae-Hong Ko ◽  
Wanjun Gu ◽  
Inja Lim ◽  
Hyoweon Bang ◽  
Eun A. Ko ◽  
...  
Keyword(s):  
Gene Expression ◽  
Lung Adenocarcinoma ◽  
Ion Channel ◽  
Potential Role ◽  
Channel Gene ◽  
Ion Channel Gene

scholarly journals Crispri Ion Channel Gene Modulation in Human iPSC-Cardiomyocytes

2020 ◽  
Vol 118 (3) ◽  
pp. 569a
Author(s):  
Julie L. Han ◽  
Emilia Entcheva
Keyword(s):  
Ion Channel ◽  
Gene Modulation ◽  
Channel Gene ◽  
Human Ipsc ◽  
Ion Channel Gene

scholarly journals A microbial TRP-like polycystic-kidney-disease-related ion channel gene

2005 ◽  
Vol 387 (1) ◽  
pp. 211-219 ◽  
Author(s):  
Christopher P. PALMER ◽  
Ebru AYDAR ◽  
Mustafa B. A. DJAMGOZ
Keyword(s):  
Cell Wall ◽  
Kidney Disease ◽  
Ion Channel ◽  
Polycystic Kidney Disease ◽  
Transient Receptor Potential ◽  
Receptor Potential ◽  
Cell Wall Synthesis ◽  
Polycystic Kidney ◽  
Channel Gene ◽  
Ion Channel Gene

Ion channel genes have been discovered in many microbial organisms. We have investigated a microbial TRP (transient receptor potential) ion channel gene which has most similarity to polycystic-kidney-disease-related ion channel genes. We have shown that this gene (pkd2) is essential for cellular viability, and is involved in cell growth and cell wall synthesis. Expression of this gene increases following damage to the cell wall. This fission yeast pkd2 gene, orthologues of which are found in all eukaryotic cells, appears to be a key signalling component in the regulation of cell shape and cell wall synthesis in yeast through an interaction with a Rho1-GTPase. A model for the mode of action of this Schizosaccharomyces pombe protein in a Ca2+ signalling pathway is hypothesized.

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