Dynamic motion analysis of magnetic particles in microfluidic systems under an external gradient magnetic field

2017 ◽  
Vol 21 (2) ◽  
Author(s):  
Quanliang Cao ◽  
Mengyu Liu ◽  
Zhen Wang ◽  
Xiaotao Han ◽  
Liang Li
2020 ◽  
Vol 20 (2) ◽  
pp. 50-58 ◽  
Author(s):  
Andrej Krafcik ◽  
Peter Babinec ◽  
Melania Babincova ◽  
Ivan Frollo

AbstractLungs are used as an attractive possibility for administration of different therapeutic substances for a long time. An innovative method of such administration widely studied nowadays is the application of aerosolized magnetic particles as the carriers to the lungs in the external non-homogeneous magnetic field. For these reasons we have studied dynamics of such a system on a level of particle trajectory in air in the presence of magnetic force as a driving force exerted on micrometric magnetic particle. On two typical examples of magnetically driven systems—motion of magnetic particle in a gradient magnetic field and cyclotron-like motion of a charged particle in homogeneous magnetic field in microscale, where the external accelerating forces are very large and the relevant time scale is of the order from fraction of milliseconds to seconds, we have examined the importance of these forces. As has been shown, for particles with high initial acceleration, not only the commonly used Stokes force but also the Basset history force should be used for correct description of the motion.


2017 ◽  
Vol 140 (1) ◽  
Author(s):  
Junfeng Lu ◽  
Wen-Qiang Lu

To design a better adsorption performance in a novel magnetic adsorption device used for hemodialysis (HD), the mechanical properties of magnetic absorbents trapped inside a two-phase system are studied in this paper. A gradient magnetic coil field is assumed to produce the magnetic driving force that balances other hydraulic forces for the adsorbents. For this field, a related winding equation for the solenoid coil is obtained in our previous work; and a complement practical form of the winding equation is derived in this paper. Case studies are also described in this paper to explore the design aspects of the field.


2017 ◽  
Vol 19 (10) ◽  
Author(s):  
Carlos David Amaya-Jaramillo ◽  
Adriana Patricia Pérez-Portilla ◽  
José Javier Serrano-Olmedo ◽  
Milagros Ramos-Gómez

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Weizhong Wei ◽  
Zhen Wang

Finite element numerical simulations were carried out in 2D geometry to calculate the magnetic force on magnetic nanoparticles under a specially fabricated electromagnet. The particle motion was modeled by a system of ordinary differential equations. The snapshots of trajectories of 4000 MNPs with and without magnetic field were analyzed and qualitatively found to be in agreement with camera visualizations of MNP movement in a container. The results of the analysis could be helpful for the design of electromagnetic field and motion analysis of magnetic particles for the delivery of magnetic materials in biomedical applications.


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