scholarly journals Erratum to: To the article “In Vitro Effect of Knotolan, a New Lignan from Abies sibirica, on the Growth of Hormone-Dependent Breast Cancer Cells” by O. S. Zhukova, L. V. Fetisova, A. V. Trishin, N. Yu. Anisimova, A. E. Shcherbakov, D. V. Yashunskii, D. E. Tsvetkov, V. M. Men’shov, M. V. Kiselevskii and N. E. Nifant’ev, Vol. 149, No. 4, pp. 511–514, October, 2010

2011 ◽  
Vol 150 (4) ◽  
pp. 556-556
Author(s):  
O. S. Zhukova ◽  
L. V. Fetisova ◽  
A. V. Trishin ◽  
N. Yu. Anisimova ◽  
A. M. Scherbakov ◽  
...  
2010 ◽  
Vol 149 (4) ◽  
pp. 511-514 ◽  
Author(s):  
O. S. Zhukova ◽  
L. V. Fetisova ◽  
A. V. Trishin ◽  
N. Yu. Anisimova ◽  
A. E. Shcherbakov ◽  
...  

RSC Advances ◽  
2016 ◽  
Vol 6 (115) ◽  
pp. 114906-114915 ◽  
Author(s):  
Durba Ganguly ◽  
Chetan Kumar Jain ◽  
Ramesh Chandra Santra ◽  
Susanta Roychoudhury ◽  
Hemanta Kumar Majumder ◽  
...  

Reductive cleavage of azo bond in a CoIIcomplex of HPIA decreased significantly implying less toxicity. On human colon carcinoma HCT116, ALL MOLT-4 & MCF-7 breast cancer cells complex was more effective than HPIA but less toxic towards normal cells.


2012 ◽  
Vol 23 ◽  
pp. ii44
Author(s):  
O.S. Zhukova ◽  
A.M. Shcherbakov ◽  
L.V. Fetisova ◽  
M.V. Kiselevskii ◽  
N.E. Nifantiev

2020 ◽  
Vol 6 (2) ◽  
Author(s):  
Lisni Noraida Waruwu ◽  
Maria Bintang ◽  
Bambang Pontjo Priosoeryanto

Green tea (Camellia sinensis) is one of traditional plants that have the potential as an anticancer. The sample used in this research commercial green tea extract. The purpose of this study was to test the antiproliferation activity of green tea extract on breast cancer cell MCM-B2 in vitro. Green tea extract fractionated using three solvents, ie water, ethanol 70%, and n-hexane. Extract and fraction of green tea water have value Lethality Concentration 50 (LC50) more than 1000 ppm. The fraction of ethanol 70% and n-hexane had an LC50 value of 883.48 ppm and 600.56 ppm, respectively. The results of the phytochemical screening of green tea extract are flavonoids, tannins, and saponins, while the phytochemical screening results of n-hexane fraction are flavonoids and tannins. Antiproliferation activity was tested on breast cancer cells MCM-B2 and normal cells Vero by trypan blue staining method. The highest MCM-B2 cell inhibitory activity was achieved at a concentration of 13000 ppm green tea extract and 1000 ppm of n-hexane fraction, 59% and 59%, respectively. The extract and n-hexane fraction of green tea are not toxic to normal Vero cells characterized by not inhibiting normal cell proliferation. Keywords: antiproliferative, cancer cell MCM-B2, commercial green tea, cytotoxicity


2020 ◽  
Vol 21 (14) ◽  
pp. 1528-1538
Author(s):  
Sarah Albogami ◽  
Hadeer Darwish ◽  
Hala M. Abdelmigid ◽  
Saqer Alotaibi ◽  
Ahmed Nour El-Deen ◽  
...  

Background: In Saudi Arabia, the incidence and mortality rates of breast cancer are high. Although current treatments are effective, breast cancer cells develop resistance to these treatments. Numerous studies have demonstrated that active compounds in plant extracts, such as the phenolic compound Rosmarinic Acid (RA), exert anti-cancer effects. Objective: We investigated the anticancer properties of methanolic crude extracts of seedlings and calli of Rosmarinus officinalis and Coleus hybridus, two Lamiaceae species. Methods: MCF-7 human breast cancer cells were treated with methanolic crude extracts obtained from plant calli and seedlings generated in vitro, and cell proliferation was evaluated. Transcriptional profiling of the seedling and callus tissues was also conducted. Results: The mRNA expression levels of RA genes were higher in C. hybridus seedlings than in R. officinalis seedlings, as well as in C. hybridus calli than in R. officinalis calli, except for TAT and C4H. In addition, seedling and callus extracts of both R. officinalis and C. hybridus showed anti-proliferative effects against MCF-7 cells after 24 or 48 h of treatment. Discussion: At a low concentration of 10 μg/mL, C. hybridus calli and seedling extracts showed the most significant anti-proliferative effects after 24 and 48 h of exposure (p < 0.01); controls (doxorubicin) also showed significant inhibition, but lesser than that observed with C. hybridus (p < 0.05). Results with R. officinalis callus and seedling extracts did not significantly differ from those with untreated cells. Conclusion: Methanolic extracts of R. officinalis and C. hybridus are potentially valuable options for breast cancer treatment.


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