MRI-Based and Histologically Verified 3D Modeling of Spatial Distribution of Intra-Arterially Transplanted Cells in Rat Brain

2021 ◽  
Author(s):  
I. L. Gubskiy ◽  
D. D. Namestnikova ◽  
K. K. Sukhinich ◽  
V. A. Revkova ◽  
P. A. Melnikov ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Rat Brain ◽  
3D Modeling

MRI-based and histologically verified 3D modeling of the spatial distribution of intra-arterially

2021 ◽  
pp. 90-96
Author(s):  
I. L. Gubskiy ◽  
◽  
D. D. Namestnikova ◽  
K. K. Sukhinich ◽  
V. A. Revkova ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
3D Modeling

scholarly journals 3D Modeling of Discontinuity in the Spatial Distribution of Apartment Prices Using Voronoi Diagrams

2020 ◽  
Vol 12 (2) ◽  
pp. 229 ◽  
Author(s):  
Mirosław Bełej ◽  
Marta Figurska
Keyword(s):  
Spatial Distribution ◽  
Real Estate ◽  
Housing Market ◽  
3D Modeling ◽  
3D Visualization ◽  
Voronoi Diagrams ◽  
Capital City ◽  
Data Sets ◽  
Spatial Continuity ◽  
Real Estate Prices

An immanent feature of the housing market is a large spatial dispersion of real estate prices along with their simultaneous high stratification. Application of classic methods of data interpolation results in an excessive simplification of the outcome because of a conversion of the dispersed data sets into areas of spatial continuity by reducing the above-average real estate prices. The main aim of the article was to search for spatial discontinuities of real estate prices’ distribution with 3D modeling using Voronoi diagrams as a method of irregular division of this space. Used methods of geospatial analyses with GIS tools enabled to identify clusters of high housing market activity and to avoid an excessive generalization of data resulting from the reduction of the above-average real estate prices. The research was conducted for over 7000 real estate transactions in years 2010–2017 in Olsztyn, the capital city of Warmia and Mazury in Poland, resulting in a 3D visualization of real estate prices for the chosen market, including the discontinuity in their spatial distribution.

Spatial Distribution of 5-Hydroxymethyl Cytosine in Rat Brain and Temporal Distribution in Striatum

2015 ◽  
Vol 40 (4) ◽  
pp. 688-697 ◽  
Author(s):  
Tingting Zheng ◽  
Qing Lv ◽  
Xiaoguang Lei ◽  
Xinzhen Yin ◽  
Baorong Zhang
Keyword(s):  
Spatial Distribution ◽  
Rat Brain ◽  
Temporal Distribution ◽  
Hydroxymethyl Cytosine

Determination of the spatial distribution of major elements in the rat brain with X-ray fluorescence analysis

2000 ◽  
Vol 100 (1-2) ◽  
pp. 53-62 ◽  
Author(s):  
Sentaro Takahashi ◽  
Shizuo Hatashita ◽  
Yuichi Taba ◽  
Xue-Zhi Sun ◽  
Yoshihisa Kubota ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Rat Brain ◽  
Fluorescence Analysis ◽  
Major Elements ◽  
X Ray

scholarly journals Spatial Distribution of (R)-salbutamol in Rat Brain Following Nasal and Intravenous Administration Using DESI-MS

Pharmaceutics ◽  
2020 ◽  
Vol 12 (1) ◽  
pp. 35 ◽  
Author(s):  
Rui Zhang ◽  
Jie Wu ◽  
Siyu Liu ◽  
LiangJun Deng ◽  
Junhua Hu ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Spatial Distribution ◽  
Rat Brain ◽  
Intravenous Administration ◽  
Nasal Administration ◽  
Intravenous Route ◽  
Ionization Mass ◽  
Nasal Route ◽  
Desi Ms

Recent studies have shown that β2-Adrenoreceptor is a regulator of the a-synuclein gene driving risk of Parkinson’s disease. The β2-AR agonist (R)-salbutamol, eutomer of rac-salbutamol, may hold therapeutic potential for Parkinson’s disease (PD) following nasal administration. In this study, we use desorption electrospray ionization mass spectrometry (DESI-MS) to analyze spatial distribution of (R)-salbutamol in rat brain following nasal and intravenous administration. Here, we report that (R)-salbutamol efficiently deliver to the brain and had more drug dosage exposure in rat’s brain through nasal route administration than that of intravenous route administration. In conclusion, administering (R)-salbutamol through nasal route of administration may hold advantages in improving spatial distribution and increased exposure of drug in brain.

Spatial distribution of GABABR1 receptor mRNA and binding sites in the rat brain

1999 ◽  
Vol 412 (1) ◽  
pp. 1-16 ◽  
Author(s):  
Serge Bischoff ◽  
Sabine Leonhard ◽  
Nicole Reymann ◽  
Val�rie Schuler ◽  
Ryuichi Shigemoto ◽  
...  
Keyword(s):  
Spatial Distribution ◽  
Rat Brain ◽  
Binding Sites ◽  
Receptor Mrna
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