A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing

Kelly Kyker-Snowman; Bracha Erlanger Avigdor; Mansoor Nasim; Ashley Cimino-Mathews; Sarah J. Wheelan; Pedram Argani; Ben Ho Park

doi:10.1007/s10549-018-4742-x

A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing

Breast Cancer Research and Treatment ◽

10.1007/s10549-018-4742-x ◽

2018 ◽

Vol 170 (2) ◽

pp. 425-430

Author(s):

Kelly Kyker-Snowman ◽

Bracha Erlanger Avigdor ◽

Mansoor Nasim ◽

Ashley Cimino-Mathews ◽

Sarah J. Wheelan ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Exome Sequencing ◽

Whole Exome Sequencing ◽

Primary Breast Cancer ◽

Estrogen Receptor Alpha ◽

Receptor Alpha ◽

Whole Exome ◽

Clonal Origin

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Abstract P4-14-01: Whole exome sequencing reveals greater intratumor genetic heterogeneity in primary breast cancer arising in African American compared to Caucasian women

10.1158/1538-7445.sabcs14-p4-14-01 ◽

2015 ◽

Author(s):

Tanya E Keenan ◽

Edmund A Mroz ◽

James W Rocco ◽

Leif W Ellisen ◽

Beverly Moy ◽

...

Keyword(s):

Breast Cancer ◽

African American ◽

Exome Sequencing ◽

Whole Exome Sequencing ◽

Genetic Heterogeneity ◽

Primary Breast Cancer ◽

Whole Exome ◽

Caucasian Women

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Abstract PD3-8: Whole exome sequencing reveals early mutational change on endocrine and targeted therapy in estrogen receptor (ER)-positive breast cancer

10.1158/0008-5472.sabcs13-pd3-8 ◽

2013 ◽

Author(s):

S Massarweh ◽

E Romond ◽

C Wang ◽

Z Zeng ◽

J Liu ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Targeted Therapy ◽

Exome Sequencing ◽

Whole Exome Sequencing ◽

Mutational Change ◽

Whole Exome ◽

Er Positive ◽

Positive Breast Cancer

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The effect of modifiable potentials on hypermethylation status of retinoic acid receptor-beta2 and estrogen receptor-alpha genes in primary breast cancer

Cancer Causes & Control ◽

10.1007/s10552-010-9629-z ◽

2010 ◽

Vol 21 (12) ◽

pp. 2101-2111 ◽

Cited By ~ 33

Author(s):

Saeed Pirouzpanah ◽

Forough A. Taleban ◽

Morteza Atri ◽

Ali-Reza Abadi ◽

Parvin Mehdipour

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Retinoic Acid ◽

Primary Breast Cancer ◽

Estrogen Receptor Alpha ◽

Retinoic Acid Receptor ◽

Acid Receptor ◽

Receptor Alpha

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Abstract PD9-02: Evolutionary analysis of 462 serial metastatic biopsies from 208 patients with estrogen receptor-positive (ER+) metastatic breast cancer (MBC) using whole exome sequencing (WES)

10.1158/1538-7445.sabcs18-pd9-02 ◽

2019 ◽

Author(s):

O Cohen ◽

J Buendia-Buendia ◽

S Wander ◽

U Nayar ◽

P Mao ◽

...

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Metastatic Breast Cancer ◽

Exome Sequencing ◽

Whole Exome Sequencing ◽

Metastatic Breast ◽

Evolutionary Analysis ◽

Whole Exome ◽

Estrogen Receptor Positive

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Faculty Opinions recommendation of Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4410956.7111061 ◽

2010 ◽

Author(s):

Sandra Davidge ◽

Stephane Bourque

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Cancer Growth ◽

Cardiovascular Protection ◽

Receptor Alpha ◽

Nuclear Estrogen Receptor ◽

Breast Cancer Growth

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Faculty Opinions recommendation of Non-nuclear estrogen receptor alpha signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.4410956.6051054 ◽

2010 ◽

Author(s):

Dariusz J Skarzynski ◽

Marta Siemieniuch

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Cancer Growth ◽

Cardiovascular Protection ◽

Receptor Alpha ◽

Nuclear Estrogen Receptor ◽

Breast Cancer Growth

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The Roles of Histone Deacetylase and DNA Methylation in Estrogen Receptor alpha Expression in Breast Cancer

10.21236/ada407368 ◽

2002 ◽

Author(s):

Yi Huang

Keyword(s):

Breast Cancer ◽

Dna Methylation ◽

Estrogen Receptor ◽

Histone Deacetylase ◽

Estrogen Receptor Alpha ◽

Receptor Alpha

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A Unique Breast Cancer Cell Model for Studying Reported Functions of Membrane-Localized Estrogen Receptor Alpha

10.21236/ada416093 ◽

2000 ◽

Author(s):

Adrian Lee

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Cancer Cell ◽

Breast Cancer Cell ◽

Estrogen Receptor Alpha ◽

Cell Model ◽

Receptor Alpha ◽

Breast Cancer Cell Model

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The Role of Estrogen Receptor alpha K303R Mutation in Breast Cancer Metastasis

10.21236/ada417835 ◽

2003 ◽

Author(s):

Yukun Cui ◽

Suzanne A. Fuqua

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Estrogen Receptor Alpha ◽

Cancer Metastasis ◽

Breast Cancer Metastasis ◽

Receptor Alpha

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Elucidation of Chromatin Remodeling Machinery Involved in Regulation of Estrogen Receptor Alpha Expression in Human Breast Cancer Cells

10.21236/ada442690 ◽

2005 ◽

Author(s):

Dipali Sharma

Keyword(s):

Breast Cancer ◽

Estrogen Receptor ◽

Cancer Cells ◽

Chromatin Remodeling ◽

Human Breast Cancer ◽

Breast Cancer Cells ◽

Estrogen Receptor Alpha ◽

Human Breast Cancer Cells ◽

Human Breast ◽

Receptor Alpha

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