scholarly journals Design of a point-of-care facility for diagnosis of COVID-19 using an off-grid photovoltaic system

2021 ◽  
Author(s):  
Jean Poll Alva-Araujo ◽  
Oscar Escalante-Maldonado ◽  
Ruddy Alfredo Cabrejos Ramos
Keyword(s):  
Point Of Care ◽  
Care Facility ◽  
Photovoltaic System

Rabies encephalitis

2021 ◽  
Vol 14 (4) ◽  
pp. e239249
Author(s):  
Shyam Chand Chaudhary ◽  
Akash Khandelwal ◽  
Ruchika Tandon ◽  
Kamal Kumar Sawlani
Keyword(s):  
Point Of Care ◽  
Treatment Options ◽  
Diagnostic Testing ◽  
Care Facility ◽  
Solid Organ ◽  
Mri Findings ◽  
Dismal Prognosis ◽  
Corneal Transplants ◽  
History Of

Rabies is an almost always fatal disease that physicians and patients dread due to its dismal prognosis and limited treatment options. Transmission of this disease occurs through the bite of dogs and wild animals (like jackal in our case). Other rare forms of transmission may be through inhalation in bat-infested caves and human-to-human transmission by infected corneal transplants, solid organ and tissue transplantation, and sometimes in laboratory settings. Its diagnosis is usually clinical in the absence of availability of special laboratory investigations at the point-of-care facility. Few people have described the role of imaging in diagnosis. We hereby report a patient with rabies encephalitis, having a history of jackal bite and classical MRI findings that we can use for early diagnosis in the absence of typical clinical features and specialised diagnostic testing.

Congenital Malaria in newborns delivered to Malaria-Infected mothers in hilly region of northern India: Is it really deadly?

2021 ◽  
Vol 17 ◽  
Author(s):  
Avinish Singh ◽  
Balram Ji Omar ◽  
Swathi Chacham ◽  
Jaya Chaturvedi ◽  
Sriparna Basu ◽  
...  
Keyword(s):  
Cord Blood ◽  
Point Of Care ◽  
Multivariate Logistic Regression Analysis ◽  
Care Facility ◽  
Health Care Facility ◽  
Causative Factor ◽  
Serological Tests ◽  
Northern India ◽  
Hilly Region ◽  
Congenital Malaria

Background: Malaria is endemic in many states of India. Though there are reports of maternal and congenital malaria from endemic areas, however there remains paucity of data from hilly terrains. The present study evaluated the prevalence, clinical and microbiological spectrum of maternal and congenital malaria at a tertiary health care facility in Northern India over a period of 18 months. Methods: In this observational study, mothers along with their new borns were evaluated for malaria by maternal, placental and cord blood smear examination and rapid point-of-care diagnostic serological tests. Positive cases were confirmed by polymerase chain reaction. Mother-newborn duos were followed up till discharge from hospital. Results : A total of 843 mothers delivered during the study period and were screened along with their newborns and placentae. A total of Ten (1.18%) mothers had evidence of malarial parasitemia (Plasmodium vivax, n=7 and Pl. falciparum, n=3), however none of the placental and cord blood samples were positive for malaria. Overall, 127 (15.1%) neonates required admission in neonatal intensive care unit for various morbidities. Incidence of small for gestational age (SGA) was high (n=210; 24.9%). Multivariate logistic regression analysis demonstrated maternal malaria to be an independent contributor for SGA [Odds Ratio (95% Confidence Interval), 10.7 (2.06 - 49.72)]. However, only 2% variance of SGA could be explained by maternal malaria alone. Conclusions: We report an encouragingly lower incidence of maternal malaria in mothers attending for delivery and a ‘Zero’ incidence for placental and congenital malaria during the study period as compared to national data (upto 7.4% in non-immune mothers), although maternal malaria could be a causative factor for SGA.

scholarly journals Challenges in Setting Up Point-of-Care Hemodialysis in a COVID-19 Care Facility: Lessons From a Limited-Resource Setting

2020 ◽  
Vol 5 (10) ◽  
pp. 1839-1840
Author(s):  
Joyita Bharati ◽  
Raja Ramachandran ◽  
Ram Kumar ◽  
Surya Prakash ◽  
Harbir Singh Kohli
Keyword(s):  
Point Of Care ◽  
Care Facility ◽  
Limited Resource ◽  
Limited Resource Setting ◽  
Resource Setting

scholarly journals Reliability of Point-of-Care Testing of INR in Acute Stroke

2008 ◽  
Vol 35 (3) ◽  
pp. 348-351 ◽  
Author(s):  
Theresa L. Green ◽  
Adnan Mansoor ◽  
Nancy Newcommon ◽  
Caroline Stephenson ◽  
Eileen Stewart ◽  
...  
Keyword(s):  
Emergency Department ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Correlation Coefficient ◽  
Clinical Decision Making ◽  
Point Of Care ◽  
Tertiary Care ◽  
Care Facility ◽  
Standard Laboratory ◽  
Point Of Care Testing

Background:In the emergency department, portable point-of-care testing (POCT) coagulation devices may facilitate stroke patient care by providing rapid International Normalized Ratio (INR) measurement. The objective of this study was to evaluate the reliability, validity, and impact on clinical decision-making of a POCT device for INR testing in the setting of acute ischemic stroke (AIS).Methods:A total of 150 patients (50 healthy volunteers, 51 anticoagulated patients, 49 AIS patients) were assessed in a tertiary care facility. The INR’s were measured using the Roche Coaguchek S and the standard laboratory technique.Results:The interclass correlation coefficient and 95% confidence interval between overall POCT device and standard laboratory value INRs was high (0.932 (0.69 - 0.78). In the AIS group alone, the correlation coefficient and 95% CI was also high 0.937 (0.59 - 0.74) and diagnostic accuracy of the POCT device was 94%.Conclusions:When used by a trained health professional in the emergency department to assess INR in acute ischemic stroke patients, the CoaguChek S is reliable and provides rapid results. However, as concordance with laboratory INR values decreases with higher INR values, it is recommended that with CoaguChek S INRs in the > 1.5 range, a standard laboratory measurement be used to confirm the results.

scholarly journals A Pragmatic Approach for Detecting nCOVID-19 using Pervasive Computing Based on Dual Diagnostic Measures

2021 ◽  
Vol 10 ◽  
pp. 183-193
Author(s):  
Swarnava Biswas ◽  
Chandranath Chakraborty ◽  
Riddhi Chawla ◽  
Dabosmita Paul ◽  
Debajit Sen ◽  
...  
Keyword(s):  
Language Processing ◽  
Architectural Design ◽  
Point Of Care ◽  
Care Facility ◽  
Diagnostic Technique ◽  
Way Of Life ◽  
Fusion Algorithm ◽  
Diagnostic Measures ◽  
Concurrent Algorithms ◽  
Error Percentage

Our regular way of life has been disrupted by the COVID-19, and we have been obliged to accept the procedures that are in place under the new normal regime. It is envisaged that the standard diagnostic technique will evolve throughout the course of the procedure. As a help to this type of diagnostic technique, our research group is developing a tool. In this article, the group discusses the importance of employing two diagnostic metrics that have proven to be pivotal in many diagnoses for doctors, and how they might be used to their advantage. Together, natural language processing-based symptoms measures and a machine learning-based strategy that takes into account medical vitals can help to minimise the error percentage of detection by as much as 50%. The technique suggested in this study is the first of its type, and the authors have obtained findings that are satisfactory in terms of accuracy. A further justification for suggesting such a strategy is the manner in which a fusion algorithm might arrive at the correct results from two concurrent algorithms performing the same task. One of the group's other objectives was to give the doctor a valuable opinion in the form of such an architectural design. The suggested design may be employed at any point of care facility without the need for any additional infrastructure or escalation of the current amenities to accommodate the proposed architecture.

A Regional Outbreak of Clostridium difficile PCR-Ribotype 027 Infections in Southeastern France from a Single Long-Term Care Facility

2016 ◽  
Vol 37 (11) ◽  
pp. 1337-1341 ◽  
Author(s):  
Nadim Cassir ◽  
Jean-Christophe Delarozière ◽  
Gregory Dubourg ◽  
Marion Delord ◽  
Jean-Christophe Lagier ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
Long Term Care ◽  
Point Of Care ◽  
Care Facility ◽  
Term Care ◽  
Healthcare Facilities ◽  
Long Term Care Facility ◽  
Care Facilities ◽  
Acute Care Facilities

OBJECTIVETo describe and analyze a large outbreak of Clostridium difficile 027 (CD-027) infections.METHODSConfirmed CD-027 cases were defined as CD infection plus real-time polymerase chain reaction assay (PCR) positive for CD-027. Clinical and microbiological data on patients with CD-027 infection were collected from January 2013 to December 2015 in the Provence-Alpes-Côte-d’Azur region (southeastern France).RESULTSIn total, 19 healthcare facilities reported 144 CD-027 infections (112 confirmed and 32 probable CD-027 infections) during a 22-month period outbreak. Although the incidence rate per 10,000 bed days was lower in long-term care facilities (LTCFs) than in acute care facilities (0.05 vs 0.14; P<.001), cases occurred mainly in LTCFs, one of which was the probable source of this outbreak. After centralization of CD testing, the rate of confirmed CD-027 cases from LTCFs or residential-care homes increased significantly (69% vs 92%; P<.001). Regarding confirmed CD-027 patients, the sex ratio and the median age were 0.53 and 84.2 years, respectively. The 30-day crude mortality rate was 31%. Most patients (96%) had received antibiotics within 3 months prior to the CD colitis diagnosis. During the study period, the rate of patients with CD-027 (compared with all patients tested in the point-of-care laboratories) decreased significantly (P=.03).CONCLUSIONSA large CD-027 outbreak occurred in southeastern France as a consequence of an initial cluster of cases in a single LTCF. Successful interventions included rapid isolation and testing of residents with potentially infectious diarrhea and cohorting of case patients in a specialized infectious diseases ward to optimize management.Infect Control Hosp Epidemiol 2016;1–5

Evaluation of true point of care molecular assay using fingerstick capillary whole blood for diagnosis of hepatitis C infection

2021 ◽  
Author(s):  
Reshu Agarwal ◽  
Ekta Gupta ◽  
Guresh Kumar ◽  
Keshaw Kumar Singh ◽  
Manoj Kumar Sharma
Keyword(s):  
Hepatitis C ◽  
Real Time ◽  
Whole Blood ◽  
Point Of Care ◽  
Care Facility ◽  
Health Care Facility ◽  
Reference Method ◽  
Hcv Rna ◽  
Sample Collection ◽  
Hepatitis C Infection

At present, the available point of care (POC) molecular assays for hepatitis C are not considered as true POC due to sample collection and processing requiring minimal laboratory infrastructure. A new POC Xpert HCV VL Fingerstick (Xpert FS) precludes such requirements where specimen collected by simple fingerstick can be loaded directly into the test cartridge with results available within 60 min. The present study compared the performance of this assay for HCV RNA quantitation using both capillary whole blood (CWB) and venous whole blood (VWB) with plasma HCV RNA performed on Abbott Real Time HCV PCR. CWB via fingerstick and VWB via venipuncture collected from serologically confirmed HCV-infected participants were loaded into Xpert HCV VL WB for viral load estimation. Simultaneously Abbott Real Time HCV PCR assay was also performed using plasma (reference method). Among the enrolled participants (n=157), the mean age was 46.22±14.79 years and 63 % were male. HCV RNA was detected in 100 cases (63.7 %), median 5.69 (IQR: 5.00–6.32)log10IU ml−1 on the reference method. Xpert FS showed 100 % sensitivity and specificity using both CWB and VWB. The median viral loads detected in CWB and VWB were 5.52 (IQR: 4.59–6.15) and 5.48 (IQR: 4.61–6.07)log10IU ml−1, respectively. Xpert FS offers potential as true POC enabling accurate diagnosis in a single patient visit to the health-care facility, hence may reduce the number of dropouts with a confirmed diagnosis. However, further real-time studies with larger sample size are warranted.

Plastic surgery telehealth consultation expedites Emergency Department treatment

2016 ◽  
Vol 23 (2) ◽  
pp. 321-327 ◽  
Author(s):  
Angie M Paik ◽  
Mark S Granick ◽  
Sandra Scott
Keyword(s):  
Emergency Department ◽  
Plastic Surgery ◽  
Rural Areas ◽  
Underserved Populations ◽  
Point Of Care ◽  
Care Facility ◽  
Trauma Centre ◽  
University Hospital ◽  
Care Providers ◽  
Significant Difference

Plastic surgery is a field that is particularly amenable to a telehealth milieu, as visual exam and radiographs guide proper diagnosis and management. The goals of this study were to evaluate telehealth feedback executed through an iPad app for plastic surgery-related consultations. A Quality Assurance/Quality Improvement (QA/QI) study was conducted over a 1-month period during which patients with hand injuries, facial injuries, or acute wounds presenting to the Emergency Department (ED) of a level-one trauma centre and university hospital were monitored. The study utilized a commercial iPad application through which up to four images and a brief history could be sent to a remote Plastic Surgery Educator (PSE) for evaluation. The PSE would respond with best practice information, references and videos to assist ED point-of-care providers. During the 1-month period of this study, there were 42 ED consultations for plastic surgical conditions. There was a highly significant difference in overall mean response time between consultants and PSEs (48.3 minutes vs. 8.9 minutes respectively, p < 0.001). The agreement between PSEs and consultants regarding patient assessment and care was 85.7% for in-person consultations and 100% for phone consultations. In four cases of telephone consultations, the ED providers placed splints incorrectly on hand-injured patients. Our results show that telehealth consultations to a remote plastic surgeon based on digital images and a brief history were able to produce timely and accurate responses in an emergency care facility. This design may have significant impact in rural areas, underserved populations, or regions abroad.

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