Characterization of a Murine Model System to Study MicroRNA-147 During Inflammatory Organ Injury

The Drosophila heart, also referred to as the dorsal vessel, pumps the insect blood, the hemolymph. The bilateral heart primordia develop from the most dorsally located mesodermal cells, migrate coordinately, and fuse to form the cardiac tube. Though much simpler, the fruit fly heart displays several developmental and functional similarities to the vertebrate heart and, as we discuss here, represents an attractive model system for dissecting mechanisms of cardiac aging and heart failure and identifying genes causing congenital heart diseases. Fast imaging technologies allow for the characterization of heartbeat parameters in the adult fly and there is growing evidence that cardiac dysfunction in human diseases could be reproduced and analyzed in Drosophila, as discussed here for heart defects associated with the myotonic dystrophy type 1. Overall, the power of genetics and unsuspected conservation of genes and pathways puts Drosophila at the heart of fundamental and applied cardiac research.

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Establishment and characterization of a novel murine model for head and neck cancer cachexia

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.93.0_3-p-350 ◽

2020 ◽

Vol 93 (0) ◽

pp. 3-P-350

Author(s):

Zi-Xuan Hong ◽

Kuo-Chu Lai

Keyword(s):

Head And Neck Cancer ◽

Head And Neck ◽

Neck Cancer ◽

Murine Model ◽

Cancer Cachexia

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A new model system for endometritis: Basic concepts and characterization of phenotypic and functional properties of bovine uterine neutrophils

Theriogenology ◽

10.1016/s0093-691x(96)00314-7 ◽

1996 ◽

Vol 46 (8) ◽

pp. 1339-1356 ◽

Cited By ~ 22

Author(s):

H. Zerbe ◽

H.-J. Schuberth ◽

M. Hoedemaker ◽

E. Grunert ◽

W. Leibold

Keyword(s):

Functional Properties ◽

Model System ◽

New Model ◽

Basic Concepts

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Sweat Glands and Salivary Glands as Model System for the Characterization of Monoclonal Antibodies against Differentiation Antigens of the Human Mammary Gland

Protides of the Biological Fluids ◽

10.1016/b978-0-08-030764-0.50231-7 ◽

1984 ◽

pp. 1009-1012 ◽

Cited By ~ 6

Author(s):

PH. HAGEMAN ◽

J. VAN DEN TWEEL ◽

J. HILGERS ◽

J. HILKENS ◽

H. PETERSE ◽

...

Keyword(s):

Monoclonal Antibodies ◽

Mammary Gland ◽

Salivary Glands ◽

Model System ◽

Sweat Glands ◽

Differentiation Antigens ◽

Human Mammary Gland

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Bimetallic Nanoparticles as a Model System for an Industrial NiMo Catalyst

Materials ◽

10.3390/ma12223727 ◽

2019 ◽

Vol 12 (22) ◽

pp. 3727

Author(s):

Sara Blomberg ◽

Niclas Johansson ◽

Esko Kokkonen ◽

Jenny Rissler ◽

Linnéa Kollberg ◽

...

Keyword(s):

Bimetallic Nanoparticles ◽

Model System ◽

Native Oxide ◽

Oxide Shell ◽

Industrial System ◽

Narrow Size Distribution ◽

Nimo Catalysts ◽

Further Development ◽

Industrial Relevance

An in-depth understanding of the reaction mechanism is required for the further development of Mo-based catalysts for biobased feedstocks. However, fundamental studies of industrial catalysts are challenging, and simplified systems are often used without direct comparison to their industrial counterparts. Here, we report on size-selected bimetallic NiMo nanoparticles as a candidate for a model catalyst that is directly compared to the industrial system to evaluate their industrial relevance. Both the nanoparticles and industrial supported NiMo catalysts were characterized using surface- and bulk-sensitive techniques. We found that the active Ni and Mo metals in the industrial catalyst are well dispersed and well mixed on the support, and that the interaction between Ni and Mo promotes the reduction of the Mo oxide. We successfully produced 25 nm NiMo alloyed nanoparticles with a narrow size distribution. Characterization of the nanoparticles showed that they have a metallic core with a native oxide shell with a high potential for use as a model system for fundamental studies of hydrotreating catalysts for biobased feedstocks.

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