scholarly journals Characterization of a Murine Model System to Study MicroRNA-147 During Inflammatory Organ Injury

Inflammation ◽  
2021 ◽  
Author(s):  
Boyun Kim ◽  
Victor Guaregua ◽  
Xuebo Chen ◽  
Chad Zhao ◽  
Wanyi Yeow ◽  
...  
Keyword(s):  
Murine Model ◽  
Model System ◽  
Organ Injury

Farber disease: characterization of behavior and brain pathology in a new murine model

2014 ◽  
Vol 111 (2) ◽  
pp. S93
Author(s):  
Tomo Sawada ◽  
Shaalee Dworski ◽  
Jakub Sikora ◽  
Matthew Micsenyi ◽  
Jeffrey A. Medin ◽  
...  
Keyword(s):  
Murine Model ◽  
Brain Pathology ◽  
Farber Disease

scholarly journals Drosophila Heart as a Model for Cardiac Development and Diseases

Cells ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 3078
Author(s):  
Anissa Souidi ◽  
Krzysztof Jagla
Keyword(s):  
Cardiac Dysfunction ◽  
Congenital Heart ◽  
Cardiac Development ◽  
Heart Diseases ◽  
Heart Defects ◽  
Fruit Fly ◽  
Model System ◽  
Fast Imaging

The Drosophila heart, also referred to as the dorsal vessel, pumps the insect blood, the hemolymph. The bilateral heart primordia develop from the most dorsally located mesodermal cells, migrate coordinately, and fuse to form the cardiac tube. Though much simpler, the fruit fly heart displays several developmental and functional similarities to the vertebrate heart and, as we discuss here, represents an attractive model system for dissecting mechanisms of cardiac aging and heart failure and identifying genes causing congenital heart diseases. Fast imaging technologies allow for the characterization of heartbeat parameters in the adult fly and there is growing evidence that cardiac dysfunction in human diseases could be reproduced and analyzed in Drosophila, as discussed here for heart defects associated with the myotonic dystrophy type 1. Overall, the power of genetics and unsuspected conservation of genes and pathways puts Drosophila at the heart of fundamental and applied cardiac research.

A new model system for endometritis: Basic concepts and characterization of phenotypic and functional properties of bovine uterine neutrophils

1996 ◽  
Vol 46 (8) ◽  
pp. 1339-1356 ◽  
Author(s):  
H. Zerbe ◽  
H.-J. Schuberth ◽  
M. Hoedemaker ◽  
E. Grunert ◽  
W. Leibold
Keyword(s):  
Functional Properties ◽  
Model System ◽  
New Model ◽  
Basic Concepts

scholarly journals Bimetallic Nanoparticles as a Model System for an Industrial NiMo Catalyst

Materials ◽  
2019 ◽  
Vol 12 (22) ◽  
pp. 3727
Author(s):  
Sara Blomberg ◽  
Niclas Johansson ◽  
Esko Kokkonen ◽  
Jenny Rissler ◽  
Linnéa Kollberg ◽  
...  
Keyword(s):  
Bimetallic Nanoparticles ◽  
Model System ◽  
Native Oxide ◽  
Oxide Shell ◽  
Industrial System ◽  
Narrow Size Distribution ◽  
Nimo Catalysts ◽  
Further Development ◽  
Industrial Relevance

An in-depth understanding of the reaction mechanism is required for the further development of Mo-based catalysts for biobased feedstocks. However, fundamental studies of industrial catalysts are challenging, and simplified systems are often used without direct comparison to their industrial counterparts. Here, we report on size-selected bimetallic NiMo nanoparticles as a candidate for a model catalyst that is directly compared to the industrial system to evaluate their industrial relevance. Both the nanoparticles and industrial supported NiMo catalysts were characterized using surface- and bulk-sensitive techniques. We found that the active Ni and Mo metals in the industrial catalyst are well dispersed and well mixed on the support, and that the interaction between Ni and Mo promotes the reduction of the Mo oxide. We successfully produced 25 nm NiMo alloyed nanoparticles with a narrow size distribution. Characterization of the nanoparticles showed that they have a metallic core with a native oxide shell with a high potential for use as a model system for fundamental studies of hydrotreating catalysts for biobased feedstocks.

scholarly journals Correction: Chronic Alcohol Ingestion Increases Mortality and Organ Injury in a Murine Model of Septic Peritonitis

PLoS ONE ◽  
2020 ◽  
Vol 15 (9) ◽  
pp. e0239568
Author(s):  
Benyam P. Yoseph ◽  
Elise Breed ◽  
Christian E. Overgaard ◽  
Christina J. Ward ◽  
Zhe Liang ◽  
...  
Keyword(s):  
Murine Model ◽  
Alcohol Ingestion ◽  
Organ Injury ◽  
Chronic Alcohol ◽  
Septic Peritonitis ◽  
Chronic Alcohol Ingestion
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