Amphiphilic tumor-targeting chimeric peptide-based drug self-delivery nanomicelles for overcoming drug resistance in cancer by synergistic chemo-photodynamic therapy

2020 ◽  
Vol 55 (31) ◽  
pp. 15288-15298
Author(s):  
Pei-Ling Chen ◽  
Shi-Li Peng ◽  
Li-Ting Wu ◽  
Ming-Ming Fan ◽  
Ping Wang ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Photodynamic Therapy ◽  
Tumor Targeting ◽  
Chimeric Peptide

Mitochondria and plasma membrane dual-targeted chimeric peptide for single-agent synergistic photodynamic therapy

Biomaterials ◽  
2019 ◽  
Vol 188 ◽  
pp. 1-11 ◽  
Author(s):  
Hong Cheng ◽  
Rong-Rong Zheng ◽  
Gui-Ling Fan ◽  
Jing-Hao Fan ◽  
Lin-Ping Zhao ◽  
...  
Keyword(s):  
Plasma Membrane ◽  
Photodynamic Therapy ◽  
Single Agent ◽  
Chimeric Peptide

Towards the Synthesis of New Tumor Targeting Photosensitizers for Photodynamic Therapy and Imaging Applications

2017 ◽  
Vol 2 (1) ◽  
pp. 190-200 ◽  
Author(s):  
Giuliana Mion ◽  
Cristina Mari ◽  
Tatiana Da Ros ◽  
Riccardo Rubbiani ◽  
Gilles Gasser ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Tumor Targeting

scholarly journals The role of photodynamic therapy in overcoming cancer drug resistance

2015 ◽  
Vol 14 (8) ◽  
pp. 1476-1491 ◽  
Author(s):  
Bryan Q. Spring ◽  
Imran Rizvi ◽  
Nan Xu ◽  
Tayyaba Hasan
Keyword(s):  
Drug Resistance ◽  
Photodynamic Therapy ◽  
Cancer Cells ◽  
Cancer Drug ◽  
Cancer Drug Resistance

This perspective highlights unique mechanisms of photodynamic therapy (PDT) that can be utilized to overcome classical drug resistance and re-sensitize resistant cancer cells for standard therapies.

scholarly journals A nuclear targeted dual-photosensitizer for drug-resistant cancer therapy with NIR activated multiple ROS

2016 ◽  
Vol 7 (7) ◽  
pp. 4237-4244 ◽  
Author(s):  
Zhengze Yu ◽  
Wei Pan ◽  
Na Li ◽  
Bo Tang
Keyword(s):  
Reactive Oxygen Species ◽  
Drug Resistance ◽  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Laser Irradiation ◽  
Multidrug Resistant ◽  
Drug Resistant ◽  
Oxygen Species ◽  
Cancer Multiple ◽  
Nir Laser

A nuclear targeted dual-photosensitizer was developed for photodynamic therapy against multidrug resistant cancer. Multiple reactive oxygen species (ROS) could be generated in the nucleus to directly break DNA double strands with a single 980 nm NIR laser irradiation, regardless of drug resistance.

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