Effect of chitosan-gluconic acid conjugate/poly(vinyl alcohol) cryogels as wound dressing on partial-thickness wounds in diabetic rats

2013 ◽  
Vol 24 (10) ◽  
pp. 2479-2487 ◽  
Author(s):  
Takayuki Takei ◽  
Hideki Nakahara ◽  
Sadao Tanaka ◽  
Hiroto Nishimata ◽  
Masahiro Yoshida ◽  
...  
Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.


Burns ◽  
2014 ◽  
Vol 40 (8) ◽  
pp. 1668-1678 ◽  
Author(s):  
Gang Zhou ◽  
Ruhan A. ◽  
Heng Ge ◽  
Lin Wang ◽  
Meili Liu ◽  
...  

1996 ◽  
Vol 19 (6) ◽  
pp. 897-900 ◽  
Author(s):  
Toshikiro KIMURA ◽  
Kazunari SATO ◽  
Katsuyoshi SUGIMOTO ◽  
Ritsuko TAO ◽  
Tsuyoshi MURAKAMI ◽  
...  

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