Poly(vinyl alcohol) Hydrogel/Chitosan-Modified Clay Nanocomposites for Wound Dressing Application and Controlled Drug Release

2019 ◽  
Vol 27 (3) ◽  
pp. 290-300 ◽  
Author(s):  
Samira Feiz ◽  
Amir H. Navarchian
Keyword(s):  
Drug Release ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Controlled Drug Release ◽  
Poly Vinyl Alcohol ◽  
Clay Nanocomposites ◽  
Modified Clay

Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug release

2019 ◽  
Vol 54 (10) ◽  
pp. 7867-7882
Author(s):  
Francisca Villanueva-Flores ◽  
Margarita Miranda-Hernández ◽  
José O. Flores-Flores ◽  
Alberto Porras-Sanjuanico ◽  
Hailin Hu ◽  
...  
Keyword(s):  
Cell Culture ◽  
Drug Release ◽  
Vinyl Acetate ◽  
Mammalian Cell ◽  
Vinyl Alcohol ◽  
Mammalian Cell Culture ◽  
Controlled Drug Release ◽  
Poly Vinyl Alcohol ◽  
Novel Scaffold

Controlled drug release through carboxymethyl-chitosan/poly(vinyl alcohol) blend films

2007 ◽  
Vol 47 (9) ◽  
pp. 1373-1379 ◽  
Author(s):  
Ling-Chong Wang ◽  
Xi-Guang Chen ◽  
Le-Jun Yu ◽  
Pi-Wu Li
Keyword(s):  
Drug Release ◽  
Vinyl Alcohol ◽  
Controlled Drug Release ◽  
Carboxymethyl Chitosan ◽  
Poly Vinyl Alcohol ◽  
Blend Films

scholarly journals Novel Hydrogels of Chitosan and Poly (vinyl alcohol) Reinforced with Inorganic Particles of Bioactive Glass

Polymers ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 691
Author(s):  
O. Sánchez-Aguinagalde ◽  
Ainhoa Lejardi ◽  
Emilio Meaurio ◽  
Rebeca Hernández ◽  
Carmen Mijangos ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Drug Release ◽  
Bioactive Glass ◽  
Vinyl Alcohol ◽  
Release Kinetics ◽  
The Body ◽  
Poly Vinyl Alcohol ◽  
X Ray Diffraction ◽  
Inorganic Particles ◽  
Release Studies

Chitosan (CS) and poly (vinyl alcohol) (PVA) hydrogels, a polymeric system that shows a broad potential in biomedical applications, were developed. Despite the advantages they present, their mechanical properties are insufficient to support the loads that appear on the body. Thus, it was proposed to reinforce these gels with inorganic glass particles (BG) in order to improve mechanical properties and bioactivity and to see how this reinforcement affects levofloxacin drug release kinetics. Scanning electron microscopy (SEM), X-ray diffraction (XRD), swelling tests, rheology and drug release studies characterized the resulting hydrogels. The experimental results verified the bioactivity of these gels, showed an improvement of the mechanical properties and proved that the added bioactive glass does affect the release kinetics.

scholarly journals Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Cellular Adhesion ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Hybrid Nanofibers

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.

Poly(acrylic acid)-block-poly(vinyl alcohol) anchored maghemite nanoparticles designed for multi-stimuli triggered drug release

Nanoscale ◽  
2013 ◽  
Vol 5 (23) ◽  
pp. 11464 ◽  
Author(s):  
Ji Liu ◽  
Christophe Detrembleur ◽  
Antoine Debuigne ◽  
Marie-Claire De Pauw-Gillet ◽  
Stéphane Mornet ◽  
...  
Keyword(s):  
Drug Release ◽  
Acrylic Acid ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Maghemite Nanoparticles ◽  
Triggered Drug Release ◽  
Poly Acrylic Acid

Drug-loaded ultrafine poly(vinyl alcohol) fibre mats prepared by electrospinning

e-Polymers ◽  
2005 ◽  
Vol 5 (1) ◽  
Author(s):  
Chunxue Zhang ◽  
Xiaoyan Yuan ◽  
Lili Wu ◽  
Jing Sheng
Keyword(s):  
Drug Release ◽  
Photoelectron Spectroscopy ◽  
Vinyl Alcohol ◽  
Phosphate Buffer Solution ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Buffer Solution ◽  
Drug Molecules ◽  
Alcohol Fibre

AbstractSubmicron poly(vinyl alcohol) (PVA) fibre mats embedded with Aspirin and bovine serum albumin (BSA) were prepared by electrospinning of their aqueous solutions. Fibre morphology was investigated by scanning electron microscopy. The composition of the fibre mats was characterized by Fourier transform IR spectroscopy and X-ray photoelectron spectroscopy. The in vitro drug release was investigated by immersing the fibre mats in phosphate buffer solution at 37°C. Results indicated that the morphology of fibre mats was influenced by the amount of drug, and more beaded and irregularly shaped fibres were found with increasing drug amounts. There were drug molecules distributed on the surface of the PVA fibres. Studies of in vitro drug release showed that both Aspirin and BSA were released more quickly from PVA fibre mats than from PVA films because of the large surface area and high porosity of the fibre mats.

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