What About the Little Ones? Systematic Review of Cognitive and Behavioral Outcomes Following Early TBI

2022 ◽  
Author(s):  
M. Séguin ◽  
C. Gagner ◽  
C. Tuerk ◽  
J. Lacombe Barrios ◽  
P. MacKay ◽  
...  
Keyword(s):  
Systematic Review ◽  
Behavioral Outcomes

A Systematic Review of Sleep and Circadian Rhythms in Children with Attention Deficit Hyperactivity Disorder

2021 ◽  
pp. 108705472097855
Author(s):  
Upasana Bondopadhyay ◽  
Unai Diaz-Orueta ◽  
Andrew N. Coogan
Keyword(s):  
Systematic Review ◽  
Circadian Rhythms ◽  
Sleep Disturbances ◽  
Behavioral Outcomes ◽  
Future Research ◽  
Narrative Synthesis ◽  
Adhd Symptoms ◽  
Children With Adhd ◽  
Hyperactivity Disorder ◽  
Form Part

Objective: Children and adults with ADHD often report sleep disturbances that may form part of the etiology and/or symptomatology of ADHD. We review the evidence for sleep changes in children with ADHD. Methods: Systematic review with narrative synthesis assessing sleep and circadian function in children aged 5 to 13 years old with a diagnosis of ADHD. Results: 148 studies were included for review, incorporating data from 42,353 children. We found that sleep disturbances in ADHD are common and that they may worsen behavioral outcomes; moreover, sleep interventions may improve ADHD symptoms, and pharmacotherapy for ADHD may impact sleep. Conclusion: Sleep disturbance may represent a clinically important feature of ADHD in children, which might be therapeutically targeted in a useful way. There are a number of important gaps in the literature. We set out a manifesto for future research in the area of sleep, circadian rhythms, and ADHD.

scholarly journals SMARTPHONE ADDICTION AND BEHAVIORAL OUTCOMES IN SOUTH KOREA: A SYSTEMATIC REVIEW AND META-ANALYSIS

2021 ◽  
Vol 9 (2) ◽  
pp. 358-369
Author(s):  
Asad Shahjehan ◽  
Sajjad Ahmad Afridi ◽  
Maqsood Haider ◽  
Amjad Iqbal ◽  
Shahab Aziz
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Behavioral Outcomes ◽  
Smartphone Addiction ◽  
Positive Outcomes ◽  
The South ◽  
South Korean ◽  
Behavior Outcomes ◽  
Considerable Debate ◽  
Country Specific

Purpose of the study: There is considerable debate on smartphone addiction and its relationship with behavioral outcomes however in literature there is only one meta-analysis in the country-specific context and none in the South Korean context. Ranked 6th based on smartphone penetration in the world it is imperative to quantify the association. Methodology: A systematic review was conducted to collect published sources about smartphone addiction and its relationships with behavioral outcomes. The identified sources were evaluated for appropriateness and inclusion in the meta-analysis was made. Thirty-one studies were included in the Meta-analysis providing data from 32 samples (n=11,002) and presented associations with 13 behavioral outcomes. Main Findings: Meta-analytical tests presented a positive and significant relationship between smartphone addiction and the overall subject’s behavioral outcomes. Among the behavioral outcomes identified through the systematic review, six had significant while seven had an insignificant association with smartphone addiction. Lastly, these behavioral outcomes were quantitatively classified into 6 groups based on direction, significance, and heterogeneity of their reported effects. Overall smartphone addiction has a significant role in modifying certain behaviors of an individual. Applications of this study: The results of this study enforce the opinion that smartphone addiction tends to significantly enhance negative behavioral outcomes while limits positive outcomes in the South Korean population. Novelty/Originality of this study: This is the first country-specific study conducted regarding smartphone addiction. This is also the first meta-analysis study conducted which evaluated the effects of smartphone addiction on multiple behavior outcomes.

scholarly journals A Systematic Review of Behavioral Outcomes for Leadership Interventions Among Health Professionals

2020 ◽  
Vol 28 (5) ◽  
pp. e118
Author(s):  
Michelle CLEARY ◽  
Rachel KORNHABER ◽  
Deependra Kaji THAPA ◽  
Sancia WEST ◽  
Denis VISENTIN
Keyword(s):  
Systematic Review ◽  
Health Professionals ◽  
Behavioral Outcomes

Abstract TP345: A Systematic Review of Statins in Animal Models of Intracerebral Hemorrhage and Proposal of a Modified STAIR Criteria for Evaluation of Preclinical Studies in ICH

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Dominic A Nistal ◽  
Christopher P Kellner ◽  
Daniel Wei ◽  
Diana Herrera ◽  
J D Mocco
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Intracerebral Hemorrhage ◽  
Randomized Clinical Trials ◽  
Behavioral Outcomes ◽  
Severe Form ◽  
P Value ◽  
Preclinical Studies ◽  
Hematoma Volume ◽  
Preclinical Trials

Background and Purpose: Intracerebral hemorrhage (ICH) is a severe form of stroke with limited medical and surgical treatment. Similarly to clinical trials in acute stroke, none of the medications that appeared promising in preclinical testing have panned out in human clinical trials. HMG-CoA reductase inhibitors (e.g. statins) show promise as a therapy for ICH in both animal and human studies. Our aim is to review and assess the quality of preclinical studies on the role of statins in ICH recovery. Methods: We identified preclinical trials assessing the efficacy of statins in ICH via a systematic review of the literature according to PRISMA guidelines. In total, 16 studies were identified that described the use of statins in an animal model of ICH and assessed changes in histological outcomes, behavioral scores, or both. Design characteristics were analyzed using Stroke Therapy Academic Industry Roundtable (STAIR) criteria modified for ICH. Results: Behavioral outcomes were assessed in 12 of the studies with 100% (n=12) reporting statins significantly improved ICH recovery. Histological hematoma volume and histological Brain Water Content (BWC) outcomes were analyzed in 10 of the studies with 50% (n=5) reporting significant improvement. There was no correlation between STAIR Quality Score and behavioral, histological hematoma volume, and histological BWC outcomes across all studies (n=16), (p=0.75, p-value=0.49, p=0.44). Conclusions: Behavioral outcomes in ICH were found to consistently improve with administration of statins suggesting that this medication may be suitable for randomized clinical trials in humans. In addition, the STAIR criteria can be modified to effectively evaluate preclinical studies in ICH. Key words: Intracerebral hemorrhage, Intraparenchymal hemorrhage, ICH, stroke, statins, neuroprotection, animal, preclinical trials, review, systematic review

scholarly journals Psychosocial and behavioral outcomes of genomic testing in cancer: a systematic review

2018 ◽  
Vol 27 (1) ◽  
pp. 28-35 ◽  
Author(s):  
Tatiane Yanes ◽  
Amanda M. Willis ◽  
Bettina Meiser ◽  
Katherine M. Tucker ◽  
Megan Best
Keyword(s):  
Systematic Review ◽  
Behavioral Outcomes ◽  
Genomic Testing

scholarly journals The Impact of Breast Density Information or Notification on Women's Cognitive, Psychological, and Behavioral Outcomes: A Systematic Review

2021 ◽  
Author(s):  
Brooke Nickel ◽  
Tessa Copp ◽  
Meagan Brennan ◽  
Rachel Farber ◽  
Kirsten McCaffery ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Systematic Review ◽  
Breast Density ◽  
Controlled Trial ◽  
Behavioral Outcomes ◽  
The United States ◽  
Disadvantaged Communities ◽  
Study Team ◽  
Randomised Controlled ◽  
The Impact

Abstract Background Breast density (BD) is an independent risk factor for breast cancer and reduces the sensitivity of mammography. This systematic review aims to synthesize evidence from existing studies to understand the impact of BD information and/or notification on women's cognitive, psychological and behavioral outcomes. Methods Studies were identified via relevant database searches up to March 2020. Two authors evaluated the eligibility of studies with verification from the study team, extracted and crosschecked data, and assessed the risk of bias. Results Of the 1134 titles identified, 29 studies were included. Twenty-three studies were quantitative, including only 1 randomised controlled trial of women receiving BD information, and 6 were qualitative. Twenty-seven studies were conducted in the United States, with 19 conducted post-BD legislation. The overall results in terms of BD awareness, knowledge, attitudes, perceptions and intentions were heterogeneous across included studies, with the strongest consistency demonstrated regarding the importance of communication with and involvement of healthcare professionals. Together the studies did however highlight that there is still limited awareness of BD in the community, especially in more socio-economic disadvantaged communities, and limited knowledge about what BD means and the implications for women. Importantly, BD information in the context of overall breast cancer risk has not yet been studied. Conclusions There are important gaps in the understanding of the impact of BD information or notification on women and how best to communicate BD information to women. More high-quality evidence to inform both current and future practice related to BD is still needed.

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