The diagnostic yield of D-Dimer in relation to time from symptom onset in patients evaluated for venous thromboembolism in the emergency medicine department

2010 ◽  
Vol 31 (1) ◽  
pp. 1-5 ◽  
Author(s):  
Yelena Goldin ◽  
Oren Pasvolsky ◽  
Ori Rogowski ◽  
Itzhak Shapira ◽  
Arie Steinvil ◽  
...  
2007 ◽  
Vol 122 ◽  
pp. S118
Author(s):  
Itzhak Shapira ◽  
Yelena Goldin ◽  
Ori Rogowski ◽  
Pinchas Halpern ◽  
Jack Serov ◽  
...  

2007 ◽  
Vol 8 (1) ◽  
pp. 101
Author(s):  
I. Shapira ◽  
Y. Goldin ◽  
O. Rogowski ◽  
P. Halpern ◽  
J. Serov ◽  
...  

Author(s):  
Karan B. Shah ◽  
Sapna D. Gupta ◽  
Devang A. Rana ◽  
Supriya D. Malhotra ◽  
Pankaj R. Patel

Background: Electrolytes play an important role in various physiological functions of the body. Electrolyte disturbances are one of the most common problems encountered in critically ill patients. Drugs are also known to cause adverse electrolyte consequences. These drugs could be anti-hypertensive agents, hormones, antipsychotics or steroids. There is paucity of published literature on electrolyte disturbances caused by drugs. The purpose of our study was to evaluate the electrolyte disturbances caused by various drugs in critically ill patients.Methods: Following approval of the Institutional Ethics Committee, data collection was started. Adverse Drug Reactions (ADRs) presenting as an electrolyte disturbance in emergency medicine department or occurring in hospitalized patients in the Intensive care unit (ICU) of our hospital was be collected. ADRs resulting into electrolyte disturbances were identified and analysed in detail for demographic details, types of electrolyte disturbances, seriousness, severity, causality and preventability of ADRs. Fisher's exact test was done to find out the statistical difference between the electrolyte disturbances and different drugs.Results: Total 58 ADRs were reported as an electrolyte disturbance. Mean age of the patients affected was 52.48 years. Highest number of ADRs were observed in the age group of 61 to 70 years. Hypokalemia constituted 32 cases (55.2%) followed by hyponatremia (25.9%), hyperkalemia (6.9%), hypernatremia (6.9%), hypocalcemia (1.7%), hypomagnesemia (1.7%) and hypophosphatemia (1.7%). Insulin was associated with maximum cases of ADRs (27.6%).Conclusions: Electrolyte disturbances constitutes a major chunk of ADRs especially in critically ill patients. The physicians must be well-versed with the dynamics of fluid-electrolyte balance.


2019 ◽  
Vol 9 (4) ◽  
pp. 165-171
Author(s):  
Ramadhani Jumanne Mashoka ◽  
Brittany Murray ◽  
Upendo George ◽  
Natalia Lobue ◽  
Juma Mfinanga ◽  
...  

2009 ◽  
Vol 03 (01) ◽  
pp. 37
Author(s):  
Domenico Prisco ◽  
Elisa Grifoni ◽  
Daniela Poli ◽  
◽  
◽  
...  

With its high sensitivity and negative predictive value, D-dimer (DD) testing has gained a role in the diagnostic work-up of suspected venous thromboembolism (VTE) for the exclusion of the disease, potentially reducing the need for imaging tests. The diagnostic yield of DD testing is affected not only by the choice of the appropriate assay for its measurement, but also by patient characteristics. As a consequence, its clinical usefulness for the exclusion of suspected VTE should be carefully evaluated in special clinical settings. There is increasing evidence that DD testing after anticoagulation withdrawal for a first unprovoked VTE episode may be useful to identify patients at higher risk of recurrence, and may help clinicians with the decision of whether to continue or stop anticoagulant treatment. However, further studies are needed to establish the optimal timing of DD testing and the best DD cut-off level that predicts recurrence, and to develop a clinical prediction rule for recurrent VTE.


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