Prevalence of bovine tuberculosis in pastoral cattle herds in the Oromia region, southern Ethiopia

Bovine tuberculosis (bTB) remains a significant endemic pathogen of cattle herds, despite multi-decadal control programmes being in place in several countries. Understanding the risks of future bTB breakdown (BD) and the associated characteristics of herds and index breakdowns could help inform risk categorisation. Such risk categories could then contribute to tailored management and policies. Here, we estimated the future risk of herd BD for the cohort of herds that were derestricted during 2013 in Ireland using multivariable logit regression models, with a dominance analysis approach. One third of herds that were derestricted in 2013 experienced a breakdown during the follow-up five year period (1469/4459; 33%). BD length was a significant predictor of future risk, primarily driven by long BDs > 230 days relative to short BDs < 130 days (OR 95%CI: 1.157–1.851), as was having had a previous BD (OR 95%CI: 1.012–1.366). Herd-size was the dominant predictor of future risk (accounted for 46% of predicted variance), suggesting significant increase in risk of future breakdown with increasing (log) herd-size (OR 95%CI: 1.378–1.609). There was significant spatial variation in future risk across counties, and it was the second most dominant predictor of future risk (25% of predicted variance). The size of index breakdowns was not a strong predictor of future risk over a 5-year period. These findings can inform a risk-based policy development.

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Evaluation of the sensitivity and specificity of bovine tuberculosis diagnostic tests in naturally infected cattle herds using a Bayesian approach

Veterinary Microbiology ◽

10.1016/j.vetmic.2011.07.034 ◽

2012 ◽

Vol 155 (1) ◽

pp. 38-43 ◽

Cited By ~ 51

Author(s):

Julio Álvarez ◽

Andrés Perez ◽

Javier Bezos ◽

Sergio Marqués ◽

Anna Grau ◽

...

Keyword(s):

Sensitivity And Specificity ◽

Bayesian Approach ◽

Bovine Tuberculosis ◽

Diagnostic Tests ◽

Infected Cattle ◽

Cattle Herds

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Epidemiology of bovine tuberculosis in Butajira, Southern Ethiopia: A cross-sectional abattoir-based study

African Journal of Microbiology Research ◽

10.5897/ajmr2013.6259 ◽

2014 ◽

Vol 8 (33) ◽

pp. 3112-3117 ◽

Cited By ~ 3

Author(s):

Nemomsa Biratu ◽

Gebrezgabiher Gebremedhin ◽

Birhanu Tadesse ◽

Tadelle Habtamu ◽

Tadesse Gebrehiwot ◽

...

Keyword(s):

Bovine Tuberculosis ◽

Southern Ethiopia ◽

Cross Sectional

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Bovine tuberculosis and its risk factors among dairy cattle herds in and around Bahir Dar City, Northwest Ethiopia

Ethiopian Veterinary Journal ◽

10.4314/evj.v19i2.3 ◽

2015 ◽

Vol 19 (2) ◽

pp. 27 ◽

Cited By ~ 10

Author(s):

Anwar Nuru ◽

Gezahegne Mamo ◽

Leakemariam Teshome ◽

Aboma Zewdie ◽

Girmay Medhin ◽

...

Keyword(s):

Risk Factors ◽

Dairy Cattle ◽

Bovine Tuberculosis ◽

Northwest Ethiopia ◽

Bahir Dar ◽

Cattle Herds

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Assessment of the specificity of a gamma-interferon test performed with specific antigens to detect bovine tuberculosis, after non-negative results to intradermal tuberculin testing

Veterinary Record Open ◽

10.1136/vetreco-2019-000335 ◽

2019 ◽

Vol 6 (1) ◽

pp. e000335 ◽

Cited By ~ 1

Author(s):

Anne Praud ◽

Clémence Bourély ◽

Maria-Laura Boschiroli ◽

Barbara Dufour

Keyword(s):

Bovine Tuberculosis ◽

Gamma Interferon ◽

Skin Tests ◽

Negative Results ◽

In Series ◽

Specific Antigens ◽

Ifn Γ ◽

Tuberculin Testing ◽

Cattle Herds ◽

Higher Sensitivity

In cattle herds in France, cervical skin tests (STs) using simple intradermal tuberculin (SIT) are performed to detect bovine tuberculosis (bTB). When positive results are found on ST screening, the herd is considered to be ‘under suspicion’ and confined, raising economic issues. The suspicion can be lifted by carrying out a single intradermal cervical comparative test (SICCT) at least six weeks later.The authors conducted an experimental study in France between 2013 and 2015 to assess the accuracy of the gamma-interferon test (IFN-γ), used in series after a non-negative result to ST screening, and to study the possibility of replacing the SICCT performed six weeks later by an IFN performed within a few days. Data were collected concerning 40 infected and 1825 bTB-free animals from herds with non-negative results to ST screening. This study showed that the IFN-γ test based on specific antigens and performed within a few days of a non-negative result to the ST has higher sensitivity than the SICCT performed six weeks later and equal specificity. The IFN test is more convenient to perform; however, it is more expensive. The IFN-γ test based on MIX antigens may be a useful alternative to the SICCT, to shorten the confinement period of suspect herds without underdetecting bTB.

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