Toxicological effects of Sphaeranthus indicus Linn. (Asteraceae) leaf essential oil against human disease vectors, Culex quinquefasciatus Say and Aedes aegypti Linn., and impacts on a beneficial mosquito predator

The aim of this work was to prepare a nanoemulsion containing the essential oil of Protium heptaphyllum resin and to evaluate the larvicidal activity and the residual larvicidal effect against Aedes aegypti. The essential oil was identified by gas chromatography coupled to a mass spectrometer, and the nanoemulsions were prepared using a low-energy method and characterized by photon correlation spectroscopy. The results indicated the major constituents as p-cimene (27.70%) and α-Pinene (22.31%). Nanoemulsions had kinetic stability and a monomodal distribution in a hydrophilic-lipophilic balance of 14 with particle diameters of 115.56 ± 1.68 nn and zeta potential of −29.63 ± 3.46 mV. The nanoemulsion showed larvicidal action with LC50 = 2.91 µg∙mL−1 and residual larvicidal effect for 72 h after application to A. aegypti larvae. Consequently, the nanobiotechnological product derived from the essential oil of P. heptaphyllum resin could be used against infectious disease vectors.

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Chemical Composition and Biting Deterrent Activity of Essential Oil of Tagetes patula (Marigold) against Aedes aegypti

Natural Product Communications ◽

10.1177/1934578x1601101028 ◽

2016 ◽

Vol 11 (10) ◽

pp. 1934578X1601101

Author(s):

Abbas Ali ◽

Nurhayat Tabanca ◽

Elham Amin ◽

Betul Demirci ◽

Ikhlas A. Khan

Keyword(s):

Essential Oil ◽

Aedes Aegypti ◽

Tagetes Patula ◽

Caryophyllene Oxide ◽

Leaf Essential Oil ◽

Main Components ◽

Deterrent Activity ◽

Module System

The hydrodistilled leaf essential oil (EO) of Tagetes patula L. was analyzed by GC-FID and GC-MS. The main components of the oil were characterized as caryophyllene oxide (18.4%), β-caryophyllene (18.0%) and spathulenol (9.1%). The EO was screened for its biting deterrent activity against Aedes aegypti L. using the in vitro K&D module system. T. patula EO exhibited good biting deterrent activity. The results suggest that these sesquiterpenes may contribute to biting deterrent activity, but the role of minor components cannot be excluded. T. patula EO also showed 100, 90 and 10% mortality at dosages of 125, 62.5 and 31.25 ppm, respectively, in 1-day-old larvae of Ae. aegypti.

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Insecticidal and Attractant Activities of Magnolia citrata Leaf Essential Oil against Two Major Pests from Diptera: Aedes aegypti (Culicidae) and Ceratitis capitata (Tephritidae)

Molecules ◽

10.3390/molecules26082311 ◽

2021 ◽

Vol 26 (8) ◽

pp. 2311

Author(s):

Ngoc Anh Luu-Dam ◽

Nurhayat Tabanca ◽

Alden S. Estep ◽

Duy Hung Nguyen ◽

Paul E. Kendra

Keyword(s):

Puerto Rico ◽

Essential Oil ◽

Aedes Aegypti ◽

Insecticidal Activity ◽

Ceratitis Capitata ◽

Fruit Fly ◽

Positive Control ◽

Sterile Male ◽

Leaf Essential Oil ◽

First Time

In this study, Magnolia citrata Noot and Chalermglin (Magnoliaceae) essential oil (MCEO) was evaluated for insecticidal activity against the yellow fever mosquito Aedes aegypti and attractant activity for the Mediterranean fruit fly Ceratitis capitata. The leaves of Magnolia citrata (Giổi chanh) were collected from northwestern Vietnam, and the water-distilled MCEO was analyzed by gas-chromatography and mass spectrometry (GC-MS). The major constituents of MCEO were identified as linalool 19%, geranial 16%, citronellal 14%, neral 14%, and sabinene 12%. MCEO showed 100% mortality at 1 μg/μL against 1st instar larvae of Ae. aegypti (Orlando strain, ORL), and the oil exhibited 54% (ORL) and 68% (Puerto Rico strain) mortality at 5 μg/mosquito against Ae. aegypti adult females. Initial screens showed that MCEO had weak insecticidal activity compared to the positive control permethrin. In bioassays with sterile male C. capitata, MCEO exhibited moderately strong attraction, comparable to that observed with a positive control, Tetradenia riparia essential oil (TREO). Herein, the insecticidal and attractant activities of MCEO are reported for the first time.

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Sodium channel activation underlies transfluthrin repellency in Aedes aegypti

PLoS Neglected Tropical Diseases ◽

10.1371/journal.pntd.0009546 ◽

2021 ◽

Vol 15 (7) ◽

pp. e0009546

Author(s):

Felipe Andreazza ◽

Wilson R. Valbon ◽

Qiang Wang ◽

Feng Liu ◽

Peng Xu ◽

...

Keyword(s):

Aedes Aegypti ◽

Sodium Channel ◽

Sodium Channels ◽

Human Disease ◽

Disease Vectors ◽

Channel Activation ◽

Principal Mechanism ◽

Pyrethroid Insecticides ◽

Voltage Gated Sodium Channels ◽

Sodium Channel Activation

Background Volatile pyrethroid insecticides, such as transfluthrin, have received increasing attention for their potent repellent activities in recent years for controlling human disease vectors. It has been long understood that pyrethroids kill insects by promoting activation and inhibiting inactivation of voltage-gated sodium channels. However, the mechanism of pyrethroid repellency remains poorly understood and controversial. Methodology/Principal findings Here, we show that transfluthrin repels Aedes aegypti in a hand-in-cage assay at nonlethal concentrations as low as 1 ppm. Contrary to a previous report, transfluthrin does not elicit any electroantennogram (EAG) responses, indicating that it does not activate olfactory receptor neurons (ORNs). The 1S-cis isomer of transfluthrin, which does not activate sodium channels, does not elicit repellency. Mutations in the sodium channel gene that reduce the potency of transfluthrin on sodium channels decrease transfluthrin repellency but do not affect repellency by DEET. Furthermore, transfluthrin enhances DEET repellency. Conclusions/Significance These results provide a surprising example that sodium channel activation alone is sufficient to potently repel mosquitoes. Our findings of sodium channel activation as the principal mechanism of transfluthrin repellency and potentiation of DEET repellency have broad implications in future development of a new generation of dual-target repellent formulations to more effectively repel a variety of human disease vectors.

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Efficacy of essential oil from Cananga odorata (Lamk.) Hook.f. & Thomson (Annonaceae) against three mosquito species Aedes aegypti (L.), Anopheles dirus (Peyton and Harrison), and Culex quinquefasciatus (Say)

Parasitology Research ◽

10.1007/s00436-015-4699-1 ◽

2015 ◽

Vol 114 (12) ◽

pp. 4531-4543 ◽

Cited By ~ 15

Author(s):

Mayura Soonwera

Keyword(s):

Essential Oil ◽

Aedes Aegypti ◽

Culex Quinquefasciatus ◽

Mosquito Species ◽

Anopheles Dirus ◽

Cananga Odorata

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