scholarly journals Correction to: Adverse effect of rheumatoid arthritis on male Wistar rat’s fertility: protective role of Costus extract

2021 ◽  
Author(s):  
Samar Kamel ◽  
Hend M. Tag ◽  
Hala Ebeid ◽  
Howayda E. Khaled ◽  
Amani A. Almallah ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Adverse Effect ◽  
Protective Role

scholarly journals Adverse effect of rheumatoid arthritis on male Wistar rat’s fertility: protective role of Costus extract

2021 ◽  
Author(s):  
Samar Kamel ◽  
Hend M. Tag ◽  
Hala Ebeid ◽  
Howayda E. Khaled ◽  
Amani A Almallah ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Adverse Effect ◽  
Protective Role

Protective role of theophylline and their interaction with nitric oxide (NO) in adjuvant-induced rheumatoid arthritis in rats

2015 ◽  
Vol 29 (2) ◽  
pp. 854-862 ◽  
Author(s):  
Rishi Pal ◽  
Manju J. Chaudhary ◽  
Prafulla C. Tiwari ◽  
Suresh Babu ◽  
K.K. Pant
Keyword(s):  
Rheumatoid Arthritis ◽  
Nitric Oxide ◽  
Protective Role

scholarly journals Potential Adverse Effect of Ultrasound on the Electroretinogram of Retina and the Protective Role of Different Types of Antioxidants

2020 ◽  
Vol 8 (2) ◽  
pp. 20
Author(s):  
Ayman Ahmed ◽  
Mervat Ahmed Ali ◽  
Mona Mostafa Gamal ◽  
Abdel Sattar Mohamed Sallam ◽  
Elsayed Mahmoud Elsayed
Keyword(s):  
Adverse Effect ◽  
Protective Role ◽  
Potential Adverse Effect ◽  
Different Types

scholarly journals The Protective Role of Wheat Germ Oil Against Adverse Effect of Deltamethrin on Reproductive Aspects of Male Albino Rats

2021 ◽  
Vol 6 (3) ◽  
pp. 70-75
Author(s):  
Abeer M. Radi ◽  
Naglaa Abdel-Azeem ◽  
Ismail Mostafa ◽  
Nermeen Helmy ◽  
Walaa Ahmed
Keyword(s):  
Adverse Effect ◽  
Wheat Germ ◽  
Protective Role ◽  
Albino Rats ◽  
Wheat Germ Oil

scholarly journals Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models

2018 ◽  
Vol 9 ◽  
Author(s):  
Claire E. J. Waterborg ◽  
Silke Beermann ◽  
Mathijs G. A. Broeren ◽  
Miranda B. Bennink ◽  
Marije I. Koenders ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Tyrosine Kinase ◽  
Protective Role ◽  
Arthritis Models ◽  
Mer Tyrosine Kinase

scholarly journals Evidence for a protective role of the human leukocyte antigen class II region in early rheumatoid arthritis

Rheumatology ◽  
2001 ◽  
Vol 40 (2) ◽  
pp. 133-139 ◽  
Author(s):  
K. Vos ◽  
I. E. van der Horst‐Bruinsma ◽  
J. M. W. Hazes ◽  
F. C. Breedveld ◽  
S. le Cessie ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Human Leukocyte Antigen ◽  
Early Rheumatoid Arthritis ◽  
Human Leukocyte Antigen Class ◽  
Human Leukocyte ◽  
Class Ii ◽  
Protective Role ◽  
Leukocyte Antigen

The Protective Role of Inhibition of Keratin on Rheumatoid Arthritis

2019 ◽  
Vol 9 (6) ◽  
pp. 797-803
Author(s):  
Yan Zhao ◽  
Lanxiu Yang ◽  
Jihong Pan ◽  
Huan Zhang ◽  
Guodong Sun ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Flow Cytometric Analysis ◽  
Protective Role ◽  
Invasion And Migration ◽  
Flow Cytometric ◽  
Migratory Capacity ◽  
Synovial Tissues ◽  
And Migration ◽  
Fibroblast Like Synoviocytes

Objective: Rheumatoid arthritis (RA) is a common inflammatory disease. Studies showed that keratin type II cuticular Hb4 (KRT84) was highly expressed in the synovial membrane of patients with RA. However, the function and mechanism of KRT84 in RA is still unclear. Methods: In this study, we isolated fibroblast-like synoviocytes (FLS) from the mixed knee joint synovial tissues from five patients with RA and the cells were treated with KRT84 siRNA. After transfection of 24 h and 36 h, the knockdown efficiency and expression of relevant genes was detected by RT-PCR. MTT assay, transwell assay, wound scratch assays, flow cytometric analysis and ELISA were used to assess cell proliferation, invasive and migratory capacity. Results: We found that the invasion and migration of RAFLS were significantly decreased after transfection of KRT84 siRNA. ELISA showed a remarkably decrease in TNF-α secretion after KRT84 knockdown. We also explore stimulatory factors for high expression of KRT84 in RA. The inhibitors of ERK, STAT3 and NF-κ B pathways were employed. Our results showed that the expression of KRT84 in RAFLS was evidently increased after treatment with ERK and STAT3 pathway inhibitor. Conclusions: These results imply a protective role of KRT84 knockdown on RA and lay a foundation for further studies on the pathogenetic mechanisms of RA.

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