scholarly journals In vitro assay of cytoskeleton nanomechanics as a tool for screening potential anticancer effects of natural plant extract, tubeimoside I on human hepatoma (HepG2) cells

2013 ◽  
Vol 58 (21) ◽  
pp. 2576-2583 ◽  
Author(s):  
HongBo Zhao ◽  
YaShu Wang ◽  
XueMei Jiang ◽  
XiaoHao Shi ◽  
HongZhe Zhong ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
In Vitro Assay ◽  
Human Hepatoma ◽  
Vitro Assay ◽  
Natural Plant ◽  
Anticancer Effects ◽  
Human Hepatoma Hepg2 Cells ◽  
Hepatoma Hepg2 ◽  
Tubeimoside I

Natural Plant Extract Tubeimoside I Promotes Apoptosis-Mediated Cell Death in Cultured Human Hepatoma (HepG2) Cells

2011 ◽  
Vol 34 (6) ◽  
pp. 831-838 ◽  
Author(s):  
Yashu Wang ◽  
Linhong Deng ◽  
Hongzhe Zhong ◽  
Yajie Wang ◽  
Xuemei Jiang ◽  
...  
Keyword(s):  
Cell Death ◽  
Plant Extract ◽  
Hepg2 Cells ◽  
Human Hepatoma ◽  
Natural Plant ◽  
Human Hepatoma Hepg2 Cells ◽  
Hepatoma Hepg2 ◽  
Tubeimoside I

In vitro study of ultrasound on multidrug resistance in MDR human hepatoma HepG2 cells

2008 ◽  
Vol 5 (3) ◽  
pp. 165-171
Author(s):  
Qiujun Qi ◽  
Baojin Zhai ◽  
Yumian Guo ◽  
Zhihong Wang ◽  
Feng Wu
Keyword(s):  
Multidrug Resistance ◽  
Hepg2 Cells ◽  
In Vitro Study ◽  
Vitro Study ◽  
Human Hepatoma ◽  
Human Hepatoma Hepg2 Cells ◽  
Hepatoma Hepg2

scholarly journals In vitro infection of human hepatoma (HepG2) cells with hepatitis B virus.

1990 ◽  
Vol 64 (6) ◽  
pp. 3025-3032 ◽  
Author(s):  
R Bchini ◽  
F Capel ◽  
C Dauguet ◽  
S Dubanchet ◽  
M A Petit
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Hepg2 Cells ◽  
Human Hepatoma ◽  
B Virus ◽  
Human Hepatoma Hepg2 Cells ◽  
Hepatoma Hepg2

scholarly journals The Inhibitory Effect of 3β-Hydroxy-12-oleanen-27-oic Acid on Growth and Motility of Human Hepatoma HepG2 Cells through JNK and Akt Signaling Pathway

2013 ◽  
Vol 2013 ◽  
pp. 1-17 ◽  
Author(s):  
Juanjuan Wang ◽  
Xiangfeng Chen ◽  
Zhihua Zhou ◽  
Jinhui Li ◽  
Hongxiang Sun
Keyword(s):  
Hepg2 Cells ◽  
Molecular Mechanisms ◽  
Inhibitory Effect ◽  
Pcr Array ◽  
Human Hepatoma ◽  
Antitumor Effects ◽  
Human Hepatoma Hepg2 Cells ◽  
Hepatoma Hepg2

3β-Hydroxy-12-oleanen-27-oic acid (ATA) was a main antitumor active triterpene from the rhizomes ofAstilbe chinensis. In this study, we investigated its effects on growth, apoptosis, cell cycle, motility/invasion, and metatasis in human hepatoma HepG2 cellsin vitroand antimetastasis of B16-F10 melanoma in micein vivo, as well as its molecular mechanisms of action using a high-throughput Cancer Pathway Finder PCR Array. ATA could not only induce tumor cells into apoptosis through the activation of both extrinsic and intrinsic pathways, arrest HepG2 cells in G2/M phase, but also suppress the invasion and metastasis abilities of HepG2 cells and the lung metastasis of B16-F10 melanoma in mice. PCR array assay revealed that ATA upregulated 9 genes including CDKN1A, MDM2, CFLAR (CASPER), TNFRSF10B (DR5), c-Jun, IL-8, THBS1, SERPINB5 (maspin), and TNF and downregulated 8 genes such as CCNE1, AKT, ANGPT1, TEK, TGFBR1, MMP9, U-PA, and S100A4. These results indicate that ATA could exert antitumor effects through activating JNK/MAPK and suppressing AKT signal transduction pathways and that ATA might be a potent anticancer agent.

Interaction of PIG11 and Hsp60 is Involved in Apoptosis in Human Hepatoma HepG2 Cells*

2010 ◽  
Vol 37 (10) ◽  
pp. 1138-1143
Author(s):  
Xiao-Min LIU ◽  
Rong HU ◽  
Xiao-Qiu LIANG ◽  
Xiao-Juan WANG ◽  
Yan WU ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Human Hepatoma ◽  
Human Hepatoma Hepg2 Cells ◽  
Hepatoma Hepg2
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