Incidence and risk factors of cognitive impairment 3 months after first-ever stroke: A cross-sectional study of 5 geographic areas of China

ObjectivesCognitive impairment is known to have a significant impact on the quality of life of individuals and their caregivers, yet it is often underdiagnosed. The objective of this study is to assess the extent of cognitive impairment among elders visiting primary healthcare (PHC) practice settings, to explore associated risk factors and discuss current care challenges for PHC providers.DesignA cross-sectional study was conducted between March 2013 and May 2014.SettingFourteen PHC units located in rural and urban areas of the Heraklion district in Crete, Greece.ParticipantsConsecutive visitors aged at least 60 years attending selected PHC practices.Primary and secondary outcome measuresThe Mini-Mental State Examination (MMSE) was used to indicate cognitive status. Associations of low MMSE scores (≤23/24, adjusted for education level) with 12 socio-demographic factors, comorbidities and lifestyle factors were assessed.ResultsA total of 3140 PHC patients met inclusion criteria (43.2% male; mean age 73.7±7.8 years). The average MMSE score was 26.0±3.8; 26.7±3.5 in male and 25.4±3.9 in female participants (p<0.0001). Low MMSE scores were detected in 20.2% of participants; 25.9% for females vs 12.8% for males; p<0.0001. Female gender (adjusted OR (AOR)=2.72; 95% CI 2.31 to 3.47), age (AOR=1.11; 95% CI 1.10 to 1.13), having received only primary or no formal education (AOR=2.87; 95% CI 2.26 to 3.65), alcohol intake (AOR=1.19; 95% CI 1.03 to 1.37), reporting one or more sleep complaints (AOR 1.63; 95% CI 1.14 to 2.32), dyslipidaemia (AOR=0.80; 95% CI 0.65 to 0.98) and history of depression (AOR=1.90; 95% CI 1.43 to 2.52) were associated with low MMSE scores.ConclusionsThis study identified a relatively high prevalence of low MMSE scores among persons attending PHC practices in a southern European community setting and associations with several known risk factors.

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Association between Diabetes and Cognitive Function among People over 45 Years Old in China: A Cross-Sectional Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph16071294 ◽

2019 ◽

Vol 16 (7) ◽

pp. 1294 ◽

Cited By ~ 2

Author(s):

Li Zhang ◽

Jiao Yang ◽

Zhangyi Liao ◽

Xiaomeng Zhao ◽

Xuefeng Hu ◽

...

Keyword(s):

Risk Factors ◽

Cognitive Impairment ◽

Cardiovascular Risk ◽

Episodic Memory ◽

Cardiovascular Risk Factors ◽

Cross Sectional Study ◽

Age Group ◽

Sectional Study ◽

Cross Sectional ◽

Diabetes Status

Objectives: The aim of this study is to identify the relationship between diabetes status including characteristics of diabetes and cognition among the middle-aged and elderly population (≥45 years) in China. Methods: A sample of 8535 people who participated in the China Health and Retirement Longitudinal Study (CHARLS) from June 2011 to March 2012 was analyzed. Two cognitive domains including episodic memory and executive function were measured through questionnaires. People were classified into four groups: no diabetes, controlled diabetes, untreated diabetes, treated but uncontrolled diabetes. Weighted multiple regression model was conducted to explore the association between diabetes and cognition in full sample as well as three different age groups (45–59, 60–74, ≥75). Adjustments were made for demographics and cardiovascular risk factors. Results: After adjusting several covariates, untreated diabetes (β = −0.192, p < 0.05) was significantly associated with episodic memory. In the age group of 45–69 years, untreated diabetes (β = −0.471, p < 0.05) and HbA1c level (β = −0.074, p < 0.05) were significantly associated with episodic memory. When adjusting for cardiovascular risk factors, all correlations were non-significant. Conclusion: The cross-sectional study suggests that untreated diabetes and HbA1c are the potential risk factor for cognitive impairment, and these associations are more significant in the age group of 45–59 years old. Cardiovascular factors are important mediating factors in the pathway between diabetes and cognitive impairment. More longitudinal studies are needed to confirm these associations.

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Cognitive impairment and its risk factors among Myanmar elderly using the Revised Hasegawa’s Dementia Scale: A cross-sectional study in Nay Pyi Taw, Myanmar

PLoS ONE ◽

10.1371/journal.pone.0236656 ◽

2020 ◽

Vol 15 (7) ◽

pp. e0236656

Author(s):

Yu Mon Saw ◽

Thu Nandar Saw ◽

Thet Mon Than ◽

Moe Khaing ◽

Pa Pa Soe ◽

...

Keyword(s):

Risk Factors ◽

Cognitive Impairment ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Cognitive impairment among patients with diabetes in Saudi Arabia: a cross-sectional study

Middle East Current Psychiatry ◽

10.1186/s43045-020-00058-5 ◽

2020 ◽

Vol 27 (1) ◽

Author(s):

Rania Naguib ◽

Eman S. Soliman ◽

Fatima Mohammed Neimatallah ◽

Najd Sulaiman AlKhudhairy ◽

Amjad Muashaq ALGhamdi ◽

...

Keyword(s):

Risk Factors ◽

Cognitive Impairment ◽

Cross Sectional Study ◽

Diabetes Distress ◽

Sectional Study ◽

Cross Sectional ◽

Level Of Education ◽

Duration Of Diabetes ◽

Low Level ◽

Patients With Diabetes

Abstract Background The incidence of cognitive impairment (CI) is higher in patients with diabetes mellitus (DM). The association between DM and CI and the risk factors for CI need to be addressed to estimate the prevalence of cognitive impairment in patients with DM and to identify the potential risk factors. The study is a cross-sectional study using a convenient sample of 269 subjects. Sociodemographic diabetes-related variables including biochemical markers were collected. CI and diabetes-related distress (DRD) were assessed using the Arabic version of Montreal Cognitive Assessment scale (MoCA) and the Diabetes Distress Screening Scale respectively. Results Overall, 80.3% had cognitive impairment while 33.8% had severe impairment. Older age, female gender, low level of education, and low income were associated with CI; duration of diabetes and DRD were associated with CI while ophthalmic complications were associated with severe CI. Duration of diabetes was inversely associated with CI. Level of HbA1c was significantly higher in patients with severe CI, and the probability of CI increased as the level of HbA1c increased. Low level of education was associated with severe CI, and CI was two times more likely among patients with DRD. Conclusion CI was higher than worldwide figures. Elderly females with low educational level, long duration of DM, and low socioeconomic status are at more risk. The probability of severe CI increased with increased level of HbA1c. Screening for CI in patients with diabetes along with intervention programs while considering the DRD and the level of HbA1c is crucial.

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Preoperative assessment of cognitive function and risk assessment of cognitive impairment in elderly patients with orthopedics: A cross-sectional study.

10.21203/rs.3.rs-21415/v1 ◽

2020 ◽

Author(s):

Shuyuan Gan ◽

Yang Yu ◽

Jiateng Wu ◽

Xiaodong Tang ◽

Yueying Zheng ◽

...

Keyword(s):

Risk Factors ◽

Cognitive Impairment ◽

Elderly Patients ◽

Cross Sectional Study ◽

Sectional Study ◽

High Cholesterol ◽

Multivariate Logistic Regression ◽

Cross Sectional ◽

Subjective Sleep ◽

High Cholesterol Level

Abstract Background Preexisting cognitive impairment is emerging as a predictor of poor postoperative outcomes in seniors. Nevertheless, cognitive impairment in a large proportion of geriatric patients has not been well identified and diagnosed.Methods This is a cross-sectional study. Mini-mental state examination scale was used to assess cognitive function of elderly patients aged ≥ 65 years undergoing orthopedic surgery preoperatively. The baseline, living habits and laboratory examination results of the two groups were compared, and multivariate Logistic regression model was used to identify independent predictors of preoperative cognitive impairment.Results A total of 374 elderly patients with orthopedics met the inclusion criteria, and 28.61% with preoperative cognitive impairment. Multivariate Logistic regression analysis showed that age (OR=1.089, P<0.001), subjective sleep disorders (OR=1.996, P=0.021), atherosclerosis (OR=2.367, P=0.017), high cholesterol level (OR=1.373, P=0.028) were independent risk factors for preoperative cognitive impairment, while high education level performed as a protective factor (Compared with illiterate group, primary school group: OR=-0.885, P=0.009; middle school or above group: OR=-2.118, P<0.001).Conclusions The prevalence of preoperative cognitive dysfunction in geriatric elective orthopedic surgical patients was high. Our study identified venerable age, low level of education, subjective sleep disorders, atherosclerosis, high cholesterol level as risk factors for preoperative cognitive impairment in these patients. Understanding these risk factors contribute to assist in prevention and directed interventions for the high-risk population.

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