scholarly journals Preoperative assessment of cognitive function and risk assessment of cognitive impairment in elderly patients with orthopedics: A cross-sectional study.

2020 ◽  
Author(s):  
Shuyuan Gan ◽  
Yang Yu ◽  
Jiateng Wu ◽  
Xiaodong Tang ◽  
Yueying Zheng ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Elderly Patients ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
High Cholesterol ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Subjective Sleep ◽  
High Cholesterol Level

Abstract Background Preexisting cognitive impairment is emerging as a predictor of poor postoperative outcomes in seniors. Nevertheless, cognitive impairment in a large proportion of geriatric patients has not been well identified and diagnosed.Methods This is a cross-sectional study. Mini-mental state examination scale was used to assess cognitive function of elderly patients aged ≥ 65 years undergoing orthopedic surgery preoperatively. The baseline, living habits and laboratory examination results of the two groups were compared, and multivariate Logistic regression model was used to identify independent predictors of preoperative cognitive impairment.Results A total of 374 elderly patients with orthopedics met the inclusion criteria, and 28.61% with preoperative cognitive impairment. Multivariate Logistic regression analysis showed that age (OR=1.089, P<0.001), subjective sleep disorders (OR=1.996, P=0.021), atherosclerosis (OR=2.367, P=0.017), high cholesterol level (OR=1.373, P=0.028) were independent risk factors for preoperative cognitive impairment, while high education level performed as a protective factor (Compared with illiterate group, primary school group: OR=-0.885, P=0.009; middle school or above group: OR=-2.118, P<0.001).Conclusions The prevalence of preoperative cognitive dysfunction in geriatric elective orthopedic surgical patients was high. Our study identified venerable age, low level of education, subjective sleep disorders, atherosclerosis, high cholesterol level as risk factors for preoperative cognitive impairment in these patients. Understanding these risk factors contribute to assist in prevention and directed interventions for the high-risk population.

Characteristics, prevalence, risk factors, and underlying mechanism of hyponatremia in elderly patients treated with antidepressants: A cross-sectional study

Maturitas ◽  
2013 ◽  
Vol 76 (4) ◽  
pp. 357-363 ◽  
Author(s):  
Cyndie K. Mannesse ◽  
Paul A.F. Jansen ◽  
Rob J. Van Marum ◽  
Rob C. Sival ◽  
Rob M. Kok ◽  
...  
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Underlying Mechanism ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional

scholarly journals Incidence and Risk Factors of Post-Operative Delirium in Elderly Patients Who Underwent Spinal Anesthesia in Orotta, Halibet and Sembel Hospitals: A Cross Sectional Study in Eritrea

2021 ◽  
pp. 1-8
Author(s):  
Michael Beraki Mengistu ◽  
◽  
Yonatan Mehari Andemeske ◽  
AriamTsegay Emhatsion ◽  
HabtomTareke Wrieta ◽  
...  
Keyword(s):  
Risk Factors ◽  
Elderly Patients ◽  
Spinal Anesthesia ◽  
Significant Risk ◽  
Multivariate Logistic Regression Analysis ◽  
Cross Sectional Study ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
History Of

Background: Delirium is a common but often underdiagnosed set of transient symptoms often seen in elderly patients following surgeries under spinal anesthesia. With early recognition and diagnosis based on the established standard criteria delirium can be improved. Early identification of the possible contributingfactors and the magnitude of the burden will help in the management of the fragile elderly patients. The aim of this study is to determine the incidence of postoperative delirium and associated risk factors in elderly patients who have done surgery under spinal anesthesia. Method: This cross sectional study was conducted in the National Referral Hospitals and Sembel PrivateHospital, in Asmara, Eritrea from February to May, 2019. The study participants were elderly patients (age ≥65 years) having no known history of dementia or delirium or no mental disorder, no history of acute cerebrovascular disease. Basic background and clinical characteristics of the patients was collected. To assess the status of cognitive impairment level, the Mini Mental State Examination and Confusion Assessment Method tools were used. Data was collected through an interview method. After the data was entered into SPSS version 22 software, data was analyzed with frequency, percentage, bivariate and multivariate logistic regression analysis method as appropriate. P value <0.05 was considered as statistically significant. Results: The mean age of the participants was 74 ±6.62 and 102 (79.1%) of the participants were males. POD occurred in 14 (10.9%) of the patients. Adjusting all the potential factors, age was identified as arisk factor for developing POD. Conclusion: Age was determined to be a significant risk factor of delirium. Elderly patients require more attention and care and the findings might help to develop preventive strategies to the occurrence of POD

scholarly journals Cognitive impairment in a primary healthcare population: a cross-sectional study on the island of Crete, Greece

BMJ Open ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. e035551
Author(s):  
Antonios Konstantinos Bertsias ◽  
Ioanna Tsiligianni ◽  
Sophia Papadakis ◽  
Ioannis Zaganas ◽  
George Duijker ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Primary Healthcare ◽  
Urban Areas ◽  
Cross Sectional Study ◽  
Cognitive Status ◽  
Secondary Outcome ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sleep Complaints

ObjectivesCognitive impairment is known to have a significant impact on the quality of life of individuals and their caregivers, yet it is often underdiagnosed. The objective of this study is to assess the extent of cognitive impairment among elders visiting primary healthcare (PHC) practice settings, to explore associated risk factors and discuss current care challenges for PHC providers.DesignA cross-sectional study was conducted between March 2013 and May 2014.SettingFourteen PHC units located in rural and urban areas of the Heraklion district in Crete, Greece.ParticipantsConsecutive visitors aged at least 60 years attending selected PHC practices.Primary and secondary outcome measuresThe Mini-Mental State Examination (MMSE) was used to indicate cognitive status. Associations of low MMSE scores (≤23/24, adjusted for education level) with 12 socio-demographic factors, comorbidities and lifestyle factors were assessed.ResultsA total of 3140 PHC patients met inclusion criteria (43.2% male; mean age 73.7±7.8 years). The average MMSE score was 26.0±3.8; 26.7±3.5 in male and 25.4±3.9 in female participants (p<0.0001). Low MMSE scores were detected in 20.2% of participants; 25.9% for females vs 12.8% for males; p<0.0001. Female gender (adjusted OR (AOR)=2.72; 95% CI 2.31 to 3.47), age (AOR=1.11; 95% CI 1.10 to 1.13), having received only primary or no formal education (AOR=2.87; 95% CI 2.26 to 3.65), alcohol intake (AOR=1.19; 95% CI 1.03 to 1.37), reporting one or more sleep complaints (AOR 1.63; 95% CI 1.14 to 2.32), dyslipidaemia (AOR=0.80; 95% CI 0.65 to 0.98) and history of depression (AOR=1.90; 95% CI 1.43 to 2.52) were associated with low MMSE scores.ConclusionsThis study identified a relatively high prevalence of low MMSE scores among persons attending PHC practices in a southern European community setting and associations with several known risk factors.

scholarly journals Association between Diabetes and Cognitive Function among People over 45 Years Old in China: A Cross-Sectional Study

2019 ◽  
Vol 16 (7) ◽  
pp. 1294 ◽  
Author(s):  
Li Zhang ◽  
Jiao Yang ◽  
Zhangyi Liao ◽  
Xiaomeng Zhao ◽  
Xuefeng Hu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cognitive Impairment ◽  
Cardiovascular Risk ◽  
Episodic Memory ◽  
Cardiovascular Risk Factors ◽  
Cross Sectional Study ◽  
Age Group ◽  
Sectional Study ◽  
Cross Sectional ◽  
Diabetes Status

Objectives: The aim of this study is to identify the relationship between diabetes status including characteristics of diabetes and cognition among the middle-aged and elderly population (≥45 years) in China. Methods: A sample of 8535 people who participated in the China Health and Retirement Longitudinal Study (CHARLS) from June 2011 to March 2012 was analyzed. Two cognitive domains including episodic memory and executive function were measured through questionnaires. People were classified into four groups: no diabetes, controlled diabetes, untreated diabetes, treated but uncontrolled diabetes. Weighted multiple regression model was conducted to explore the association between diabetes and cognition in full sample as well as three different age groups (45–59, 60–74, ≥75). Adjustments were made for demographics and cardiovascular risk factors. Results: After adjusting several covariates, untreated diabetes (β = −0.192, p < 0.05) was significantly associated with episodic memory. In the age group of 45–69 years, untreated diabetes (β = −0.471, p < 0.05) and HbA1c level (β = −0.074, p < 0.05) were significantly associated with episodic memory. When adjusting for cardiovascular risk factors, all correlations were non-significant. Conclusion: The cross-sectional study suggests that untreated diabetes and HbA1c are the potential risk factor for cognitive impairment, and these associations are more significant in the age group of 45–59 years old. Cardiovascular factors are important mediating factors in the pathway between diabetes and cognitive impairment. More longitudinal studies are needed to confirm these associations.

Prevalence and Risk Factors of Preoperative Frailty in Chinese Elderly Inpatients with Gastrointestinal Cancer Undergoing Surgery: A Single-center Cross-sectional Study Using the Groningen Frailty Indicator

2021 ◽  
Author(s):  
Qianqian Zhang ◽  
Meng Zhang ◽  
Shaohua Hu ◽  
Lei Meng ◽  
Jing Xi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Gastrointestinal Cancer ◽  
Handgrip Strength ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Multivariate Logistic Regression ◽  
Cross Sectional ◽  
Groningen Frailty Indicator ◽  
Elderly Inpatients ◽  
Frailty Indicator

Abstract BackgroundFrailty is emerging as an important determinant for health. Compared with Western countries, research in the field of frailty started at a later stage in China and mainly focused on older community dwellers. Little is known about frailty in Chinese cancer patients, nor the risk factors of frailty. This study aimed to investigate the prevalence of frailty and its risk factors in elderly inpatients with gastrointestinal cancer. MethodsThis cross-sectional study was performed at a tertiary hospital in China from Mar. 2020 to Nov. 2020. The study enrolled 265 inpatients aged 60 and older with gastrointestinal cancer who underwent surgery. The demographic and clinical characteristics, biochemical laboratory parameters, and anthropometric data were collected from all patients. The Groningen Frailty Indicator was applied to assess the frailty status of patients. Multivariate logistic regression model analysis was carried out to identify risk factors of frailty and estimate their 95% confidence intervals. ResultsThe prevalence of frailty in elderly inpatients with gastrointestinal cancer was 43.8%. A multivariate logistic regression analysis showed that older age (OR=1.065, 95% CI: 1.001-1.132, P=0.045), low handgrip strength (OR=4.346, 95% CI: 1.739-10.863, P=0.002), no regular exercise habit (OR=3.228, 95% CI: 1.230-8.469, P=0.017), and low MNA-SF score (OR=11.090, 95% CI: 5.119-24.024, P<0.001) were risk factors of frailty. ConclusionsThis study suggested that the prevalence of frailty was high among elderly inpatients with gastrointestinal cancer. Older age, low handgrip strength, no regular exercise habit, and low MNA-SF score were identified as risk factors of frailty.

High Cholesterol Level As A Marker of Allergic Rhinitis Severity

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Dina S Sheha ◽  
Lobna A El-Korashi ◽  
Marwa M El-Begermy ◽  
Amira R Elmahdi
Keyword(s):  
Allergic Rhinitis ◽  
Cholesterol Level ◽  
Blood Lipid ◽  
Cross Sectional Study ◽  
Blood Cholesterol ◽  
Sectional Study ◽  
High Cholesterol ◽  
Blood Lipid Profile ◽  
Cross Sectional ◽  
High Cholesterol Level

Abstract Background There is some evidences illustrated the relation between abnormal blood lipid profile and atopy. But, the evidence about relation between allergic rhinitis (AR) and cholesterol level is conflicting. We aimed to assess correlation between Cholesterol level and severity of AR. Methods 50 AR patients were recruited in this cross-sectional study. Blood samples for blood cholesterol level were drawn from all patients. Results There was a statistically significant positive correlation between TC and visual analogue scale (VAS) score. Conclusion High cholesterol level in AR patients can be a marker of disease severity.

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