Effect of Electroacupuncture on Spermatogenesis in Rats with Oligozoospermia of Insufficiency of Shen (Kidney) Essence Syndrome

2018 ◽  
Vol 25 (4) ◽  
pp. 292-297 ◽  
Author(s):  
Tian-wei Cui ◽  
Mao Qin ◽  
Bao-xing Liu ◽  
Yun-xiao Gao ◽  
Wen-jing Ma ◽  
...  
Keyword(s):  
Kidney Essence

scholarly journals Analysis of Famous TCM Doctor Zan Qiang’s Experience in the Treatment of Perimenopausal Osteoporosis

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Zengrui Zhang ◽  
Bin Shao ◽  
Yanzhao Li ◽  
Qiang Zan
Keyword(s):  
Quality Of Life ◽  
Chinese Medicine ◽  
Blood Circulation ◽  
Pathological Process ◽  
Shaanxi Province ◽  
Treatment Groups ◽  
Bone Deficiency ◽  
Liver And Kidney ◽  
Kidney Essence

The purpose of this study was to analyze the clinical experience of Zan Qiang, a famous doctor of Traditional Chinese Medicine in Shaanxi province, in the treatment of perimenopausal osteoporosis. Zan believed that the main etiology and pathogenesis of perimenopausal osteoporosis were "deficiency of kidney essence, decreased marrow and bone", "deficiency of liver and kidney" and "stasis caused by deficiency". Although it is a chronic physiological disease, and the pathological process is irreversible, the treatment groups of "tonifying kidney and filling essence", "tonifying liver and tonifying kidney" and "tonifying deficiency and promoting blood circulation" can significantly improve the symptoms of patients, slow down the progress of the disease and improve the quality of life of patients.

scholarly journals Effects of “Yang-warming and kidney essence-replenishing” herbal paste on cold-related asthma exacerbation

2013 ◽  
Vol 33 (4) ◽  
pp. 468-472 ◽  
Author(s):  
Binqing Tang ◽  
Kehua Shi ◽  
Xiaoqi Li ◽  
Hongchang Wang ◽  
Hong Fang ◽  
...  
Keyword(s):  
Asthma Exacerbation ◽  
Kidney Essence

scholarly journals Treatment of Polycystic Ovary Syndrome from the Theory of "Yigui Homology"

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Xin Zhao ◽  
Mei Chen ◽  
Nan Li
Keyword(s):  
Blood Circulation ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Simultaneous Treatment ◽  
Abnormal Pregnancy ◽  
Key Factor ◽  
Liver And Kidney ◽  
Yin And Yang ◽  
Kidney Essence ◽  
Over Time

Traditional medicine believes that emotional, room labor and other factors lead to the lack of blood circulation after the weather, and the consumption of Yin blood is too much, which can lead to the deficiency of blood essence. Over time, the deficiency of menstrual blood can not nourish the kidney essence, leading to abnormal pregnancy. The liver is congenital for women, and the kidney is congenital. The disharmony of liver and kidney is the key factor of women's disease. Starting from the "homology of Yi and GUI", this paper analyzes the main etiology and pathogenesis of the disease from three aspects: deficiency of blood essence, imbalance of Zang and Xie, and Yin not controlling Yang. Following the principle of simultaneous treatment of liver and kidney, starting from the three methods of "regulating and tonifying liver and kidney, tonifying kidney and activating blood circulation, and balancing yin and Yang", the liver and kidney are reconciled, and pregnancy is sometimes the best choice. The main purpose is to benefit PCOS patients.

scholarly journals Effect of Wuzi Yanzong on Reproductive Hormones and TGF-β1/Smads Signal Pathway in Rats with Oligoasthenozoospermia

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
Zhuo Yang ◽  
Xi Zhang ◽  
Zhimin Chen ◽  
Changjiang Hu
Keyword(s):  
Serum Levels ◽  
Signal Pathway ◽  
Reproductive Hormones ◽  
Protein Levels ◽  
Underlying Mechanisms ◽  
Main Components ◽  
Kidney Essence ◽  
Histology Score ◽  
Tgf Β1

Introduction. Wuzi Yanzong (WZYZ) formula, a famous traditional Chinese medicinal prescription, has been widely used to treat kidney essence insufficiency-induced oligoasthenozoospermia in ancient and modern clinical practice. Previous studies have demonstrated that WZYZ formula exhibits significantly therapeutic activity. The aim of this study was to evaluate the effect of WZYZ formula on the reproductive hormone levels and the TGF-β1/Smads signal pathway in the testis, to explore the underlying mechanisms of WZYZ formula to improve spermatogenic function of testis in rats with oligoasthenozoospermia. Materials and Methods. In order to control the quality of the drug, the main components of the WZYZ formula were analyzed by HPLC. A rat model of oligoasthenozoospermia was established, by daily administration of tripterygium glucosides for 4 weeks, and treated with 1.62g/kg of WZYZ formula. The testes were histopathologically examined and serum levels of gonadotropin release hormone (GnRH), estradiol (E2), follicle-stimulating hormone (FSH), testosterone (T), and luteinizing hormone (LH) were measured by ELISA. TGf-β1, Smad2, and Smad4 mRNA and protein levels in the testis were evaluated by immunohistochemistry (IHC), quantitative real-time RT-PCR (qRT-PCR), and Western blotting (WB). Result. Oral administration of WZYZ formula restored testicular structure and significantly increased the histology score in the oligoasthenozoospermic rats. In addition, WZYZ also significantly increased the serum levels of GnRH, LH, E2, and T and decreased that of FSH. Meanwhile, TGf-β1, Smad2, and Sma4 expression levels were significantly decreased. Conclusions. WZYZ alleviates oligoasthenozoospermia by restoring the reproductive hormones and targeting the TGf-β1/Smads pathway.

scholarly journals Effect of Zibu Shenjing Fang () on Growth and Development of the Mouse with Kidney-essence Insufficiency and Study on the Mechanism

2011 ◽  
Vol 31 (3) ◽  
pp. 232-234 ◽  
Author(s):  
Shi-lin SHEN ◽  
Xiao-jun SU ◽  
Yu-ping WANG ◽  
Wen-hui WANG ◽  
Ji-ping SHI ◽  
...  
Keyword(s):  
Growth And Development ◽  
Kidney Essence

scholarly journals Therapeutic Effects of TianDiJingWan on the Aβ25–35-Induced Alzheimer’s Disease Model Rats

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Zhijie Li ◽  
Qing Tong ◽  
Huifang Xu ◽  
Li Hu ◽  
Rong Zhao ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Disease Model ◽  
Male Rats ◽  
Sham Operation ◽  
Therapeutic Effects ◽  
Medicine Prescription ◽  
Chinese Medicine Prescription ◽  
Biochemical Measurement ◽  
Kidney Essence ◽  
Chinese Medicine Theory

The main purpose of this study was to demonstrate the therapeutic effects and mechanism of TDJW, a modern Chinese medicine prescription developed based on the basic traditional Chinese medicine theory of “tonifying the kidney essence,” on the Aβ25–35-induced AD rats. The AD model was established by the intracerebroventricular administrations of Aβ25–35into the hippocampus CA1 tissue of SD male rats. 72 rats were randomly divided into six groups: sham operation, AD model, donepezil, high TDJW group, medium TDJW group, and low TDJW group. After oral administration of TDJW, the results of Morris water maze and step-down test showed that the learning and memory abilities of AD rats were significantly improved. And biochemical measurement demonstrated that Ach and Glu in hippocampus tissues of AD rats were increased as well. Moreover, the Aβdeposits and p-Tau aggregations in hippocampus CA1 tissues of AD rats were attenuated as observed in the micrographs of immunohistochemistry study, and the results of ELISA indicated that the expressions of TNF-α, IL-1β, and IL-6 in hippocampus tissues were significantly decreased. In conclusion, the present study demonstrated that TDJW could be used as a promising therapeutic agent for the clinical applications of AD treatment in patients.

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