scholarly journals Treatment of Polycystic Ovary Syndrome from the Theory of "Yigui Homology"

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Xin Zhao ◽  
Mei Chen ◽  
Nan Li
Keyword(s):  
Blood Circulation ◽  
Polycystic Ovary ◽  
Ovary Syndrome ◽  
Simultaneous Treatment ◽  
Abnormal Pregnancy ◽  
Key Factor ◽  
Liver And Kidney ◽  
Yin And Yang ◽  
Kidney Essence ◽  
Over Time

Traditional medicine believes that emotional, room labor and other factors lead to the lack of blood circulation after the weather, and the consumption of Yin blood is too much, which can lead to the deficiency of blood essence. Over time, the deficiency of menstrual blood can not nourish the kidney essence, leading to abnormal pregnancy. The liver is congenital for women, and the kidney is congenital. The disharmony of liver and kidney is the key factor of women's disease. Starting from the "homology of Yi and GUI", this paper analyzes the main etiology and pathogenesis of the disease from three aspects: deficiency of blood essence, imbalance of Zang and Xie, and Yin not controlling Yang. Following the principle of simultaneous treatment of liver and kidney, starting from the three methods of "regulating and tonifying liver and kidney, tonifying kidney and activating blood circulation, and balancing yin and Yang", the liver and kidney are reconciled, and pregnancy is sometimes the best choice. The main purpose is to benefit PCOS patients.

scholarly journals Changes in Glucose Tolerance over Time in Women with Polycystic Ovary Syndrome: A Controlled Study

2005 ◽  
Vol 90 (6) ◽  
pp. 3236-3242 ◽  
Author(s):  
Richard S. Legro ◽  
Carol L. Gnatuk ◽  
Allen R. Kunselman ◽  
Andrea Dunaif
Keyword(s):  
Type 2 Diabetes ◽  
Glucose Tolerance ◽  
Polycystic Ovary ◽  
Normal Glucose Tolerance ◽  
Ovary Syndrome ◽  
Normal Glucose ◽  
Pcos Group ◽  
Over Time

We performed this study to access the changes in glucose tolerance over time in a group of women with polycystic ovary syndrome (PCOS) (n = 71) and control women (n = 23) with regular menstrual cycles and baseline normal glucose tolerance. Mean follow-up was between 2 and 3 yr for both groups (PCOS 2.5 ± 1.7 yr; controls 2.9 ± 2.1 yr). Based on World Health Organization glucose tolerance categories, there was no significant difference in the prevalence of glucose intolerance at follow-up in the PCOS group. In the PCOS group, 25 (37%) had impaired glucose tolerance (IGT) and seven (10%) had type 2 diabetes mellitus at baseline, compared with 30 (45%) and 10 (15%), respectively, at follow-up. There were also no differences within groups (PCOS or control) or between groups (PCOS vs. control) in the oral glucose tolerance test-derived measure of insulin sensitivity, but in the women with PCOS who converted to either IGT or type 2 diabetes mellitus, there was a significant decrease (P < 0.0001). At the follow-up visit, the mean glycohemoglobin level was 6.1 ± 0.9% in women with PCOS vs. 5.3 ± 0.7% in the control women (P < 0.001). Women with PCOS and baseline IGT had a low conversion risk of 6% to type 2 diabetes over approximately 3 yr, or 2% per year. The effect of PCOS, given normal glucose tolerance (NGT) at baseline, is more pronounced with 16% conversion to IGT per year. Our study supports that women with PCOS (especially with NGT) should be periodically rescreened for diabetes due to worsening glucose intolerance over time, but this interval may be over several years and not annually.

scholarly journals Analysis of Famous TCM Doctor Zan Qiang’s Experience in the Treatment of Perimenopausal Osteoporosis

2021 ◽  
Vol 5 (3) ◽  
Author(s):  
Zengrui Zhang ◽  
Bin Shao ◽  
Yanzhao Li ◽  
Qiang Zan
Keyword(s):  
Quality Of Life ◽  
Chinese Medicine ◽  
Blood Circulation ◽  
Pathological Process ◽  
Shaanxi Province ◽  
Treatment Groups ◽  
Bone Deficiency ◽  
Liver And Kidney ◽  
Kidney Essence

The purpose of this study was to analyze the clinical experience of Zan Qiang, a famous doctor of Traditional Chinese Medicine in Shaanxi province, in the treatment of perimenopausal osteoporosis. Zan believed that the main etiology and pathogenesis of perimenopausal osteoporosis were "deficiency of kidney essence, decreased marrow and bone", "deficiency of liver and kidney" and "stasis caused by deficiency". Although it is a chronic physiological disease, and the pathological process is irreversible, the treatment groups of "tonifying kidney and filling essence", "tonifying liver and tonifying kidney" and "tonifying deficiency and promoting blood circulation" can significantly improve the symptoms of patients, slow down the progress of the disease and improve the quality of life of patients.

scholarly journals Berberine Phospholipid Is an Effective Insulin Sensitizer and Improves Metabolic and Hormonal Disorders in Women with Polycystic Ovary Syndrome: A One-Group Pretest–Post-Test Explanatory Study

Nutrients ◽  
2021 ◽  
Vol 13 (10) ◽  
pp. 3665
Author(s):  
Mariangela Rondanelli ◽  
Antonella Riva ◽  
Giovanna Petrangolini ◽  
Pietro Allegrini ◽  
Attilio Giacosa ◽  
...  
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Sex Hormone ◽  
Model Assessment ◽  
Ovary Syndrome ◽  
Insulin Sensitizer ◽  
Tnf Α ◽  
Post Test ◽  
Liver And Kidney ◽  
Kidney Functions

Polycystic Ovary Syndrome (PCOS) is the most frequent endocrine disease in females of reproductive age and is characterized by multifactorial unhealthy conditions related to hormonal unbalance and also to dysmetabolism and inflammation. Recently, increasing evidence has shown that natural plant-based products may play a role in PCOS management. The aim of this one-group pretest–post-test explanatory study was to evaluate, in normal–overweight PCOS women with normal menses, the effectiveness of berberine on: Insulin resistance (IR) by Homeostasis Model Assessment (HOMA); Inflammation by C-Reactive Protein (CRP), Tumor Necrosis Factor α (TNF-α); Lipid metabolism; Sex hormone profile and symptoms correlated to hyperandrogenism, such as acne, by Global Acne Grading System (GAGS) and Cardiff Acne Disability Index (CADI); Body composition by DXA. Finally, adverse effects were assessed by liver and kidney functions and creatine phosphokinase (CPK). All these parameters were collected at baseline and 60 days after supplementation with a new bioavailable and safe berberine formulation. Twelve females (aged 26.6 ± 4.9, BMI 25.3 ± 3.6) were supplied for 60 days with two tablets/day (550 mg/table) of the bioavailable berberine. Results showed a statistically significant decrease in HOMA, CRP, TNF-α, Triglycerides, testosterone, Body Mass Index (BMI), Visceral Adipose Tissue (VAT), fat mass, GAGS and CADI scores, and a statistically significant increase in sex hormone-binding globulin (SHBG). Liver and kidney functions and CPK are not statistically significantly different. Therefore, berberine can represent a safe novel dietary supplement, helpful in treatment strategy for PCOS.

scholarly journals Polycystic Ovarian Morphology in Normal Women Does Not Predict the Development of Polycystic Ovary Syndrome

2006 ◽  
Vol 91 (10) ◽  
pp. 3878-3884 ◽  
Author(s):  
M. K. Murphy ◽  
J. E. Hall ◽  
J. M. Adams ◽  
H. Lee ◽  
C. K. Welt
Keyword(s):  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Outpatient Setting ◽  
Ovary Syndrome ◽  
Ovarian Morphology ◽  
Menstrual History ◽  
Irregular Menses ◽  
Normal Women ◽  
Over Time

Abstract Context: Polycystic ovarian morphology (PCOM) is present in 25% of normal women in the absence of polycystic ovary syndrome (PCOS); however, the natural history of PCOM is unknown. Objective: We hypothesized that the presence of PCOM predisposes the development of PCOS. Design: The study was a longitudinal follow-up study over 8.2 ± 5.2 yr (mean ± sd; range 1.7–17.5 yr). Setting: The study took place in an outpatient setting. Subjects: Women who took part in a previous study as a normal control and had an ultrasound examination (n = 40) participated. Intervention: Subjects underwent an interval menstrual history, physical exam, blood sampling, and repeat ultrasound in the follicular phase. Main Outcome Measure: Development of PCOS was diagnosed by irregular menses and hyperandrogenism, in the absence of other disorders. Changes in ovarian morphology over time were evaluated. Results: At the baseline visit, 23 women (57.5%) had PCOM and 17 (42.5%) had normal ovarian morphology. One subject with PCOM developed irregular menses and presumptive PCOS. Eleven subjects with PCOM no longer met the criteria for PCOM at follow-up. There was no factor that predicted the change to normal ovarian morphology at the follow-up visit. Conclusions: These data suggest that PCOM in women with regular ovulatory cycles does not commonly predispose the development of PCOS. Although it is unusual to develop PCOM if the ovaries are normal on first assessment, ovaries in women with PCOM no longer meet the criteria for PCOM in approximately half of cases over time.

scholarly journals Heat therapy reduces sympathetic activity and improves cardiovascular risk profile in women who are obese with polycystic ovary syndrome

2019 ◽  
Vol 317 (5) ◽  
pp. R630-R640 ◽  
Author(s):  
Brett R. Ely ◽  
Michael A. Francisco ◽  
John R. Halliwill ◽  
Samantha D. Bryan ◽  
Lindan N. Comrada ◽  
...  
Keyword(s):  
Cardiovascular Risk ◽  
Wall Thickness ◽  
Sympathetic Nerve Activity ◽  
Polycystic Ovary ◽  
C Reactive Protein ◽  
Ovary Syndrome ◽  
Nerve Activity ◽  
Reactive Protein ◽  
Heat Therapy ◽  
Over Time

Polycystic ovary syndrome (PCOS) affects up to 15% of women and is associated with increased risk of obesity and cardiovascular disease. Repeated passive heat exposure [termed “heat therapy” (HT)] is a lifestyle intervention with the potential to reduce cardiovascular risk in obesity and PCOS. Women with obesity ( n = 18) with PCOS [age 27 ± 4 yr, body mass index (BMI) 41.3 ± 4.7 kg/m2] were matched for age and BMI, then assigned to HT ( n = 9) or time control (CON; n = 9). HT subjects underwent 30 one-hour hot tub sessions over 8–10 wk, whereas CON subjects did not undergo HT. Muscle sympathetic nerve activity (MSNA), blood pressure, cholesterol, C-reactive protein, and markers of vascular function were assessed at the start (Pre) and end (Post) of 8–10 wk. These measures included carotid and femoral artery wall thickness and flow-mediated dilation (FMD), measured both before and after 20 min of ischemia-20 min of reperfusion (I/R) stress. HT subjects exhibited reduced MSNA burst frequency (Pre: 20 ± 8 bursts/min, Post: 13 ± 5 bursts/min, P = 0.012), systolic (Pre: 124 ± 5 mmHg, Post: 114 ± 6 mmHg; P < 0.001) and diastolic blood pressure (Pre: 77 ± 6 mmHg, Post: 68 ± 3 mmHg; P < 0.001), C-reactive protein (Pre: 19.4 ± 13.7 nmol/L, Post: 15.2 ± 12.3 nmol/L; P = 0.018), total cholesterol (Pre: 5.4 ± 1.1 mmol/L, Post: 5.0 ± 0.8 mmol/L; P = 0.028), carotid wall thickness (Pre: 0.054 ± 0.005 cm, Post: 0.044 ± 0.005 cm; P = 0.010), and femoral wall thickness (Pre: 0.056 ± 0.009 cm, Post: 0.042 ± 0.005 cm; P = 0.003). FMD significantly improved in HT subjects over time following I/R (Pre: 5.6 ± 2.5%, Post: 9.5 ± 1.7%; P < 0.001). No parameters changed over time in CON, and BMI did not change in either group. These findings indicate that HT reduces sympathetic nerve activity, provides protection from I/R stress, and substantially improves cardiovascular risk profiles in women who are obese with PCOS.

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