scholarly journals Physical functional limitations and psychological distress in people with and without colorectal cancer: findings from a large Australian study

2020 ◽  
Vol 14 (6) ◽  
pp. 894-905 ◽  
Author(s):  
Yuehan Zhang ◽  
Grace Joshy ◽  
Kathryn Glass ◽  
Emily Banks
2021 ◽  
Vol 50 (Supplement_1) ◽  
Author(s):  
Yuehan Zhang

Abstract Background This study aims to quantify physical disability and psychological distress in people with and without colorectal cancer (CRC). Methods Questionnaire data (2006-2009) from 267,153 Australian general population members aged ≥45 years participating in the 45 and Up Study (n = 213,231 following exclusions) were linked to cancer registry and hospital admission data, to ascertain CRC status. Modified Poisson regression estimated adjusted prevalence ratios (PRs) for physical disability and psychological distress in participants with versus without CRC. Results Compared with participants without CRC (n = 210,836), CRC survivors (n = 2,395) had significantly higher disability prevalence (11.9% versus 19.5%, respectively): PR = 1.11 (95%CI=1.03-1.20); and a similar prevalence of distress (23.1% versus 20.2%): PR = 1.03 (0.94-1.20). Adverse outcomes were associated with certain clinical characteristics. Compared to participants without CRC, CRC survivors diagnosed 5-<10 and ≥10 years, with regional spread and without recent cancer treatment had similar outcomes; survivors with metastatic CRC and recent treatment had 30-60% higher prevalence of disability and distress. Compared to participants with neither CRC nor disability, PRs for distress were 4.71 (4.22-5.26) for those with disability and CRC and 4.22 (4.13-4.31) for those with disability without CRC. Conclusions Physical disability is elevated in CRC survivors. Psychological distress is elevated 4- to 5-fold with disability, regardless of CRC diagnosis, with lesser increases around diagnosis and treatment. Key message CRC survivors with less advanced disease and who have not been recently diagnosed or treated have physical disability and psychological distress comparable to the general population. Survivors with disability are at particularly high risk of distress.


2010 ◽  
Vol 23 (1) ◽  
pp. 151-160 ◽  
Author(s):  
D. Silove ◽  
R. Brooks ◽  
C. Steel Bateman ◽  
Z. Steel ◽  
Z. Fonseca C. Amaral ◽  
...  

2018 ◽  
Author(s):  
Susanne Mattsson ◽  
Erik Martin Gustaf Olsson ◽  
Maria Carlsson ◽  
Birgitta Beda Kristina Johansson

BACKGROUND Physicians and nurses in cancer care easily fail to detect symptoms of psychological distress because of barriers such as lack of time, training on screening methods, and knowledge about how to diagnose anxiety and depression. National guidelines in several countries recommend routine screening for emotional distress in patients with cancer, but in many clinics, this is not implemented. By inventing screening methods that are time-efficient, such as digitalized and automatized screenings with short instruments, we can alleviate the burden on patients and staff. OBJECTIVE The aim of this study was to compare Web-based versions of the ultrashort electronic Visual Analogue Scale (eVAS) anxiety and eVAS depression and the short Hospital Anxiety and Depression Scale (HADS) with Web-based versions of the longer Montgomery Åsberg Depression Rating Scale-Self-report (MADRS-S) and the State Trait Anxiety Inventory- State (STAI-S) with regard to their ability to identify symptoms of anxiety and depression in patients with cancer. METHODS Data were obtained from a consecutive sample of patients with newly diagnosed (<6 months) breast, prostate, or colorectal cancer or with recurrence of colorectal cancer (N=558). The patients were recruited at 4 hospitals in Sweden between April 2013 and September 2015, as part of an intervention study administered via the internet. All questionnaires were completed on the Web at the baseline assessment in the intervention study. RESULTS The ultrashort and short Web-based-delivered eVAS anxiety, eVAS depression and HADS were found to have an excellent ability to discriminate between persons with and without clinical levels of symptoms of anxiety and depression compared with recommended cutoffs of the longer instruments MADRS-S and STAI-S (area under the curve: 0.88-0.94). Cutoffs of >6 on HADS anxiety and >7 hundredths (hs) on eVAS anxiety identified patients with anxiety symptoms with high accuracy. For HADS depression, at a cutoff of >5 and eVAS depression at a cutoff of >7 hs, the accuracy was very high likewise. CONCLUSIONS The use of the short and ultrashort tools, eVAS and HADS, may be a suitable initial method of Web-based screening in busy clinical settings. However, there are still a proportion of patients who lack access to the internet or the ability to use it. There is a need to find solutions for this group to find all the patients with psychological distress.


2020 ◽  
Vol 29 (6) ◽  
pp. 1084-1091
Author(s):  
Nina C. A. Vermeer ◽  
Maxime J. M. Valk ◽  
Heleen S. Snijders ◽  
Hans F. A. Vasen ◽  
Arthur Gerritsen van der Hoop ◽  
...  

2004 ◽  
Vol 22 (14_suppl) ◽  
pp. 8181-8181 ◽  
Author(s):  
P. Heras ◽  
K. Kritikos ◽  
S. Karagiannis ◽  
P. Serenes ◽  
A. Argyriou ◽  
...  

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