The reproductive toxicity of organic compounds extracted from drinking water sources on Sprague Dawley rats: An in vitro study

2009 ◽  
Vol 25 (3) ◽  
pp. 284-293 ◽  
Author(s):  
Jiang Wu ◽  
Guanjiu Hu ◽  
Xiaoyi Wang ◽  
Dongmei Li ◽  
Hongxia Yu ◽  
...  
Keyword(s):  
Drinking Water ◽  
Organic Compounds ◽  
Reproductive Toxicity ◽  
In Vitro Study ◽  
Water Sources ◽  
Vitro Study ◽  
Sprague Dawley ◽  
Drinking Water Sources ◽  
Sprague Dawley Rats

An in vitro study on reproductive toxicity of aluminium chloride on rabbit sperm: The protective role of some antioxidants

Toxicology ◽  
2007 ◽  
Vol 239 (3) ◽  
pp. 213-223 ◽  
Author(s):  
Mokhtar I. Yousef ◽  
Kamel I. Kamel ◽  
Marwa I. El-Guendi ◽  
Fatma M. El-Demerdash
Keyword(s):  
Reproductive Toxicity ◽  
In Vitro Study ◽  
Protective Role ◽  
Vitro Study ◽  
Aluminium Chloride

scholarly journals A two-generation reproductive toxicity study of sodium molybdate dihydrate administered in drinking water or diet to Sprague-Dawley rats

2019 ◽  
Vol 84 ◽  
pp. 75-92
Author(s):  
F. Jay Murray ◽  
Frank M. Sullivan ◽  
Sue A. Hubbard ◽  
Alan M. Hoberman ◽  
Sandra Carey
Keyword(s):  
Drinking Water ◽  
Reproductive Toxicity ◽  
Sodium Molybdate ◽  
Toxicity Study ◽  
Sprague Dawley ◽  
Sprague Dawley Rats

In vitro assessment of thyroid hormone disrupting activities in drinking water sources along the Yangtze River

2013 ◽  
Vol 173 ◽  
pp. 210-215 ◽  
Author(s):  
Xinxin Hu ◽  
Wei Shi ◽  
Fengxian Zhang ◽  
Fu Cao ◽  
Guanjiu Hu ◽  
...  
Keyword(s):  
Drinking Water ◽  
Thyroid Hormone ◽  
Yangtze River ◽  
Water Sources ◽  
The Yangtze River ◽  
Drinking Water Sources ◽  
In Vitro Assessment

NaCl ingestion ameliorates plasma indexes of calcium deficiency

1997 ◽  
Vol 273 (1) ◽  
pp. R423-R432 ◽  
Author(s):  
M. G. Tordoff
Keyword(s):  
In Vitro Study ◽  
Calcium Deficiency ◽  
Ionized Calcium ◽  
Elevated Plasma ◽  
Sprague Dawley ◽  
Dihydroxyvitamin D ◽  
Sprague Dawley Rats ◽  
Nacl Concentration

Rats deprived of dietary calcium ingest large volumes of concentrated NaCl solutions. To examine why, some physiological consequences of ingesting NaCl solution were measured. Male Sprague-Dawley rats fed diet containing 150 or 25 mmol Ca2+/kg were killed at 20, 40, 80, or 160 min after they started to drink solutions of 0.125% saccharin+3% glucose (S+G), 50 mM CaCl2, or 300 mM NaCl. Relative to rats fed the 25 mmol Ca2+/kg diet given nothing to drink, those fed the same diet that drank NaCl or CaCl2 but not S+G had elevated plasma ionized calcium concentrations and reduced plasma parathyroid hormone (PTH) concentrations. Rats fed the 150 mmol Ca2+/kg diet did not show these changes. In a follow-up experiment, rats fed the 25 mmol Ca2+/kg diet that drank NaCl had elevated plasma ionized calcium and reduced PTH and 1,25-dihydroxyvitamin D concentrations over the following 4-6 h. An in vitro study found that plasma ionized calcium concentrations were modulated by NaCl concentration directly. These findings indicate that NaCl ingestion can temporarily enhance the calcium status of calcium-deprived rats.

In Vitro and In Vivo Inhibitory Effects of Alcohol on Platelet Functions of Rats Fed Dietary Saturated Fats.

1979 ◽  
Author(s):  
L. McGregor ◽  
S. Renaud
Keyword(s):  
Fatty Acids ◽  
Drinking Water ◽  
Corn Oil ◽  
Platelet Rich Plasma ◽  
Saturated Fatty Acids ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Platelet Functions

In the in vitro experiment, alcohol diluted in complete tyrode wae added, at 37°c, 2min before aggregation tests, to platelet-rich plasma (final dilution in plasma : 0.00016 and 0.00032%) from male, Sprague-Dawley rats. These animals were fed either laboratory chow or a high fat (40%) purified diet rich in either polyunsaturated fatty acids (22% corn oil) or in long chain saturated fatty acids (38% with 2% corn oil). Aggregation to thrombin but not to ADP was significantly reduced (50%) in all 3 groups of rats with 0.00032% alcohol, even in hyperaggregable animals fed saturated fats. Addition of 0.00016% alcohol slightly reduced platelet response to thrombin. The in vivo experiment consisted of feeding 48 weanling male Sprague-Dawley rats with purified diets, as mentioned above, rich in either polyunsaturated fatty acids or saturated fatty acids for at least 7 months. Morever, half of these animals had 6% alcohol in their drinking water for at least 2 months. Addition of alcohol, in drinking water, significantly prolonged platelet-rich plasma clotting time of saturated fat (101vs 136 sec) and in polyunsaturated fat group of animals (130vs 145 sec). Platelet maximal response of aggregation to thrombin (7.2vs 4.0 cm) and to ADP (9.0vs 5.7 cm) were significantly reduced by alcohol. Alcohol, in drinking water, appears to markedly inhibit platelet functions in rat. This seems to result from a direct effect on blood platelets since it can be partly reproduced by adding alcohol co platelet-rich plasma in vitro.

scholarly journals Comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry for the screening of potent swampy/septic odor-causing compounds in two drinking water sources in China

2015 ◽  
Vol 7 (6) ◽  
pp. 2458-2468 ◽  
Author(s):  
Qingyuan Guo ◽  
Xia Li ◽  
Jianwei Yu ◽  
Haifeng Zhang ◽  
Yu Zhang ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Drinking Water ◽  
Organic Compounds ◽  
Time Of Flight ◽  
Water Sources ◽  
Two Dimensional ◽  
Odor Threshold ◽  
Drinking Water Sources ◽  
Flight Mass Spectrometry

Swampy/septic odors in drinking water are normally triggered by a set of organic compounds with odor threshold concentrations (OTC) ranging from ng L−1to μg L−1.

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