scholarly journals Specific Susceptibility to COVID-19 in Adults with Down Syndrome

2021 ◽  
Author(s):  
Tomer Illouz ◽  
Arya Biragyn ◽  
Milana Frenkel-Morgenstern ◽  
Orly Weissberg ◽  
Alessandro Gorohovski ◽  
...  
Keyword(s):  
Down Syndrome ◽  
General Population ◽  
Respiratory Tract Infections ◽  
Immune Dysregulation ◽  
Social Effects ◽  
Chronic Medical Conditions ◽  
Protective Measures ◽  
Tract Infections ◽  
Specific Susceptibility

AbstractThe current SARS-CoV-2 outbreak, which causes COVID-19, is particularly devastating for individuals with chronic medical conditions, in particular those with Down Syndrome (DS) who often exhibit a higher prevalence of respiratory tract infections, immune dysregulation and potential complications. The incidence of Alzheimer’s disease (AD) is much higher in DS than in the general population, possibly increasing further the risk of COVID-19 infection and its complications. Here we provide a biological overview with regard to specific susceptibility of individuals with DS to SARS-CoV-2 infection as well as data from a recent survey on the prevalence of COVID-19 among them. We see an urgent need to protect people with DS, especially those with AD, from COVID-19 and future pandemics and focus on developing protective measures, which also include interventions by health systems worldwide for reducing the negative social effects of long-term isolation and increased periods of hospitalization.

scholarly journals The Long Term Chemotherapy with Erythromycin in Chronic Lower Respiratory Tract Infections

1986 ◽  
Vol 60 (1) ◽  
pp. 37-44 ◽  
Author(s):  
Masayoshi SAWAKI ◽  
Riichiro MIKAMI ◽  
Keiichi MIKASA ◽  
Mikikazu KUNIMATSU ◽  
Shinsaku ITO ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Lower Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Lower Respiratory Tract Infections ◽  
Tract Infections

Delayed prescribing of antibiotics for self-limiting respiratory tract infections in an urgent care out-of-hours setting

2020 ◽  
Vol 2 (3) ◽  
pp. 130-135
Author(s):  
Justine Dexter ◽  
Gerri Mortimore
Keyword(s):  
Antimicrobial Resistance ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Urgent Care ◽  
Antibiotic Prescribing ◽  
Out Of Hours ◽  
Advantages And Disadvantages ◽  
Health And Social Care ◽  
Tract Infections

Long-term overuse of antibiotics and inappropriate prescribing has led to widespread development of antimicrobial resistance. The Department of Health and Social Care recently published a five-year national action plan to reduce antimicrobial resistance, with the aim of reducing inappropriate antibiotic prescribing. This is mirrored in the NHS Long Term Plan, which aims to reduce unintentional exposure through a combination of antibiotic stewardship and leadership at all levels. An acute respiratory tract infection is one of the most common presentations in primary care, with 16.7% of all prescriptions issued attributed to it. Therefore, out-of-hours prescribers contribute significantly to general antibiotic consumption. This article analyses the practice of delayed prescribing of antibiotics for the treatment of self-limiting respiratory tract infections in an out-of-hours service. The advantages and disadvantages associated with delayed prescribing, to safely treat patients whilst facilitating the reduction of antimicrobial resistance, are discussed. In addition, recommendations for future practice are offered. This article also focuses on the development of an advanced nurse practitioner, reflecting on the four pillars of advanced practice, which underpin advanced clinical practice and associated competencies.

G372 Management of respiratory tract infections in down syndrome: A systematic review

2016 ◽  
Vol 101 (Suppl 1) ◽  
pp. A217.2-A218
Author(s):  
L Manikam ◽  
K Reed ◽  
R Venekamp ◽  
A Schilder ◽  
P Littlejohns ◽  
...  
Keyword(s):  
Systematic Review ◽  
Down Syndrome ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Tract Infections

scholarly journals Impact of Respiratory Tract Infections on Developmental Skills in Children With Down Syndrome

2011 ◽  
Vol 70 ◽  
pp. 356-356
Author(s):  
R H J Verstegen ◽  
H B M Van Gameren-Oosterom ◽  
M Fekkes ◽  
E Dusseldorp ◽  
E De Vries ◽  
...  
Keyword(s):  
Down Syndrome ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Children With Down Syndrome ◽  
Developmental Skills ◽  
Tract Infections

Long-Term Effects of Breastfeeding on Children’s Hospitalization for Respiratory Tract Infections and Diarrhea in Early Childhood in Japan

2015 ◽  
Vol 19 (9) ◽  
pp. 1956-1965 ◽  
Author(s):  
Michiyo Yamakawa ◽  
Takashi Yorifuji ◽  
Tsuguhiko Kato ◽  
Sachiko Inoue ◽  
Akiko Tokinobu ◽  
...  
Keyword(s):  
Early Childhood ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Long Term Effects ◽  
Tract Infections
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