The Effect of Vitamin A Supplementation on FoxP3 and TGF-β Gene Expression in Avonex-Treated Multiple Sclerosis Patients

2015 ◽  
Vol 56 (3) ◽  
pp. 608-612 ◽  
Author(s):  
Ali Akbar Saboor-Yaraghi ◽  
Mohammad Hossein Harirchian ◽  
Niyaz Mohammadzadeh Honarvar ◽  
Sama Bitarafan ◽  
Mina Abdolahi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Multiple Sclerosis ◽  
Vitamin A ◽  
Vitamin A Supplementation ◽  
Multiple Sclerosis Patients

Impact of Vitamin A Supplementation on RAR Gene Expression in Multiple Sclerosis Patients

2013 ◽  
Vol 51 (2) ◽  
pp. 478-484 ◽  
Author(s):  
Sama Bitarafan ◽  
Mohammad Hossein Harirchian ◽  
Mohammad Ali Sahraian ◽  
Mohammad Keramatipour ◽  
Nahid Beladi Moghadam ◽  
...  
Keyword(s):  
Gene Expression ◽  
Multiple Sclerosis ◽  
Vitamin A ◽  
Vitamin A Supplementation ◽  
Multiple Sclerosis Patients

scholarly journals The Effect of Vitamin A Supplementation on Biochemical Parameters in Multiple Sclerosis Patients

2013 ◽  
Vol 15 (3) ◽  
pp. 194-8 ◽  
Author(s):  
Sima Jafarirad ◽  
Fereydoon Siassi ◽  
Mohammad-Hossein Harirchian ◽  
Reza Amani ◽  
Sama Bitarafan ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin A ◽  
Biochemical Parameters ◽  
Vitamin A Supplementation ◽  
Multiple Sclerosis Patients

The Effect of Vitamin A Supplementation on Retinoic Acid-Related Orphan Receptor γt (RORγt) and Interleukin-17 (IL-17) Gene Expression in Avonex-Treated Multiple Sclerotic Patients

2013 ◽  
Vol 51 (3) ◽  
pp. 749-753 ◽  
Author(s):  
Niyaz Mohammadzadeh Honarvar ◽  
Mohammad Hossein Harirchian ◽  
Fariba Koohdani ◽  
Feridoun Siassi ◽  
Mina Abdolahi ◽  
...  
Keyword(s):  
Gene Expression ◽  
Retinoic Acid ◽  
Vitamin A ◽  
Orphan Receptor ◽  
Interleukin 17 ◽  
Vitamin A Supplementation

TRAIL gene expression analysis in multiple sclerosis patients

2016 ◽  
Vol 24 (1-2) ◽  
pp. 33-38 ◽  
Author(s):  
Mohammad Taheri ◽  
Shirin Nemati ◽  
Abolfazl Movafagh ◽  
Mohammad Saberi ◽  
Reza Mirfakhraie ◽  
...  
Keyword(s):  
Gene Expression ◽  
Multiple Sclerosis ◽  
Expression Analysis ◽  
Gene Expression Analysis ◽  
Multiple Sclerosis Patients

Down-regulation of RORA gene expression in the blood of multiple sclerosis patients

2018 ◽  
Vol 26 (4) ◽  
pp. 219-224 ◽  
Author(s):  
Arezou Sayad ◽  
Tayyebali Salmani ◽  
Maryam Kazemzadeh Hemmesi ◽  
Maziar Ganji ◽  
Soudeh Ghafouri-Fard ◽  
...  
Keyword(s):  
Gene Expression ◽  
Multiple Sclerosis ◽  
Down Regulation ◽  
Multiple Sclerosis Patients

scholarly journals Identification of Monotonically Differentially Expressed Genes for IFN-β-Treated Multiple Sclerosis Patients

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Suyan Tian ◽  
Lei Zhang
Keyword(s):  
Gene Expression ◽  
Multiple Sclerosis ◽  
Expression Profiles ◽  
Gene Expression Profiles ◽  
Biologically Relevant ◽  
Therapeutic Mechanism ◽  
The Central Nervous System ◽  
Multiple Sclerosis Patients ◽  
Term Response

Multiple sclerosis (MS) is a common neurological disability of the central nervous system. Immune-modulatory therapy with interferon-β (IFN-β) has been used as a first-line treatment to prevent relapses in MS patients. While the therapeutic mechanism of IFN-β has not been fully elucidated, the data of microarray experiments that collected longitudinal gene expression profiles to evaluate the long-term response of IFN-β treatment have been analyzed using statistical methods that were incapable of dealing with such data. In this study, the GeneRank method was applied to generate weighted gene expression values and the monotonically expressed genes (MEGs) for both IFN-β treatment responders and nonresponders were identified. The proposed procedure identified 13 MEGs for the responders and 2 MEGs for the nonresponders, most of which are biologically relevant to MS. Our work here provides some useful insight into the mechanism of IFN-β treatment for MS patients. A full understanding of the therapeutic mechanism will enable a more personalized treatment strategy possible.

Sign in / Sign up

Export Citation Format

Share Document