Obesity, type 2 diabetes, age, and female gender: significant risk factors in the development of alcoholic liver cirrhosis

2012 ◽  
Vol 7 (1) ◽  
pp. 280-285 ◽  
Author(s):  
Yoshinori Horie ◽  
Yoshiyuki Yamagishi ◽  
Hirotoshi Ebinuma ◽  
Toshifumi Hibi
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Liver Cirrhosis ◽  
Significant Risk ◽  
Female Gender ◽  
Alcoholic Liver Cirrhosis

scholarly journals Prevalence and risk factors of Type 2 diabetes in an urbanizing rural community of Bangladesh

1970 ◽  
Vol 33 (2) ◽  
pp. 48-54 ◽  
Author(s):  
Md. Mafuzar Rahman ◽  
Md. Abdur Rahim ◽  
Quamrun Nahar
Keyword(s):  
Risk Factors ◽  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Rural Community ◽  
Rural Areas ◽  
Fasting Blood Glucose ◽  
Significant Risk ◽  
Oral Glucose ◽  
Total Prevalence

This cross-sectional study was carried out to estimate the prevalence of type 2 diabetes mellitus and its’ risk factors in an urbanizing rural community of Bangladesh. Two villages were randomly selected from the rural areas of Gazipur district and total 975 subjects (>20 years), were included following simple random procedure. Capillary blood glucose levels, fasting blood glucose (FBG) levels and 2-hour after 75 g oral glucose load (OGTT) were measured. Height, weight, waist and hip circumferences and blood pressure were measured. The study population was lean with mean body mass index (BMI) of 20.48. The total prevalence of type 2 diabetes was 8.5%, men showed higher prevalence (9.4%) compare to women (8.0%). Increasing age and higher BMI were found to be significant risk factors following both FBG and OGTT. The study has shown that prevalence of diabetes has increased in the populations who are in transitional stage of urbanization, and may indicate an epidemiological transition due to fast expanding urbanization. Keywords: Bangladesh; Diabetes; RuralDOI: 10.3329/bmrcb.v33i2.1204Bangladesh Med Res Counc Bull 2007; 33: 48-54

scholarly journals Prevalence of chronic kidney disease stages 3-5 among patients with type 2 diabetes mellitus in Bangladesh

2017 ◽  
Vol 11 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Muhammad Abdur Rahim ◽  
Palash Mitra ◽  
Hasna Fahmima Haque ◽  
Tasrina Shamnaz Samdani ◽  
Shahana Zaman ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Chronic Kidney Disease ◽  
Type 2 Diabetes Mellitus ◽  
Kidney Disease ◽  
Glycemic Control ◽  
Significant Risk ◽  
Duration Of Diabetes

Background and objectives: Diabetes mellitus is one of the most common causes of chronic kidney disease (CKD). The prevalence of CKD in type 2 diabetes mellitus (T2DM) in Bangladesh is not well described. The present study aimed to find out the prevalence of CKD stages 3-5 and its risk factors among selected Bangladeshi T2DM patients.Methods: This cross-sectional study was conducted in BIRDEM (Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders) General Hospital, Dhaka, Bangladesh from July to December 2015. Diagnosed adult T2DM patients were consecutively and purposively included in this study. Pregnant women, patients with diagnosed kidney disease due to non-diabetic etiology, acute kidney injury (AKI), AKI on CKD and patients on renal replacement therapy were excluded. Age, gender, body mass index (BMI) and laboratory parameters were recorded systematically in a predesigned data sheet. Diagnosis of CKD and its stages were determined according to Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guidelines 2012 and estimated glomerular filtration rate (eGFR). Estimated GFR was calculated by using Modification of Diet in Renal Disease (MDRD), Cockcroft-Gault (CG) and Chronic Kidney Disease Epidemiology (CKDEPI) creatinine based formula.Results: A total of 400 patients with T2DM of various durations were enrolled in the study. Out of 400 patients, 254 (63.5%), 259 (64.75%) and 218 (54.5%) cases had CKD stages 3-5 according to MDRD, C-G and CKD-EPI equations respectively. CKD was significantly more common in females (p<0.001) and in cases with long duration of diabetes (?5 years; p=0.007). CKD stages 3-5 were significantly associated with hypertension (?2=5.2125, p =0.02) and good control of diabetes (HbA1c <7%) as evidenced by higher proportion of CKD in them (73.3%) compared to those with poor glycemic control (52.1%).Conclusions: More than half of T2DM patients had CKD stages 3-5. Female gender, duration of diabetes and hypertension were significant risk factors and should be emphasized for the prevention of CKD in T2DM. Glycemic control may not reduce CKD in diabetes.IMC J Med Sci 2017; 11(1): 19-24

scholarly journals Bone fractures in patients with type 2 diabetes mellitus: prevalence and risk factors

2017 ◽  
Vol 20 (4) ◽  
pp. 4-10
Author(s):  
Tatiana Olegovna Yalochkina ◽  
Janna Evgen'evna Belaya ◽  
Lyudmila Yakovlevna Rozhinskaya ◽  
Michail Borisovich Antsiferov ◽  
Larisa Konstantinovna Dzeranova ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Outpatient Clinic ◽  
Bone Fractures ◽  
Significant Risk ◽  
History Of ◽  
Male Sex

Aim. To estimate the prevalence of and risk factors for low-traumatic fractures in patients with type 2 diabetes mellitus (T2DM).Materials and methods. We questioned 214 patients with T2DM from a single outpatient clinic located in Moscow to evaluate the prevalence of and risk factors for low-traumatic fractures, the duration of and complications from TD2M and HbA1c levels.Results. Of 214 patients, 65 reported low-traumatic bone fractures. Patients with a history of low-traumatic fractures reported falls in the previous year (28%), whereas only 13% of patients without fractures reported falls. The difference was statistically significant, with an odds ratio of 2.34 (1,144,76), P=0,022. Men reported fractures more frequently than women (43.3% vs. 24.7%, respectively, P = 0.01). Patients with bone fractures had a lower body mass index (P = 0.022); however, a multivariate analysis revealed that a history of falls and male sex were the most significant risk factors for fracture.Conclusion. Around 30% of patients with T2DM from a Moscow outpatient clinic reported bone fractures. The most significant risk factors for fracture were a history of falls in the previous year and male sex. The article is the RePrint from the original article inDiabetes Mellitus (2016); 19(5) pp. 359-365. doi: 10.14341/DM7796

scholarly journals Effect of thiazolidinediones on insulin resistance and cardiovascular risk factors

2008 ◽  
Vol 5 (2) ◽  
pp. 2-5 ◽  
Author(s):  
T Yu Demidova ◽  
E N Erokhina
Keyword(s):  
Risk Factors ◽  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Clinical Management ◽  
Significant Risk ◽  
High Prevalence ◽  
Multivariate Control

The development of new, more effective ways of multivariate control of type 2 diabetes is currently the most important problem of endocrinology. This is caused by a high prevalence of this disease in the population, as well as a significant risk of complications leading to early morbidity and mortality of patients. Clinical management of patients with type 2 diabetes should be based on a thorough study of the mechanisms of this disease in order to correct the basic pathogenetic defects.

Lispro insulin in people with non-alcoholic liver cirrhosis and type 2 diabetes mellitus

2016 ◽  
Vol 113 ◽  
pp. 179-186 ◽  
Author(s):  
S. Gentile ◽  
G. Guarino ◽  
F. Strollo ◽  
M. Romano ◽  
S. Genovese ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Liver Cirrhosis ◽  
Alcoholic Liver Cirrhosis ◽  
Lispro Insulin

scholarly journals The Prevalence and Risk Factors of Diabetic Maculopathy in Type 2 Diabetes Mellitus: A Study From Central Nepal

2018 ◽  
Vol 4 (1) ◽  
pp. 16-21
Author(s):  
Nilam Munakarmi ◽  
Amrit Pokharel ◽  
Om Krishna Malla ◽  
Chhabindra Lal Pradhananga
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Ldl Cholesterol ◽  
Significant Risk ◽  
Diabetic Maculopathy ◽  
Cholesterol Levels

INTRODUCTION: Diabetic maculopathy is a complication of type 2 diabetes mellitus. This study was done to assess the prevalence and risk factors of Diabetic maculopathy in type 2 diabetes mellitus in Nepalese patients presenting to our hospital. MATERIAL AND METHODS: A hospital-based, descriptive, cross-sectional study was conducted at the department of ophthalmology, Kathmandu Medical College Teaching Hospital (KMCTH), Sinamangal, Kathmandu, Nepal from August, 2012 to October, 2014. 200 patients with type 2 diabetes mellitus underwent a detailed interview and a comprehensive dilated ocular evaluation by an ophthalmologist. Diabetic maculopathy was defined according to the international classification and grading system.  RESULTS: 200 patients suffering from type 2 diabetes mellitus included 90 men (45%) and 110 women (55%) of age ranging from 23 80 years (mean age = 56.23, median age = 57.5 and SD = 10.83). Diabetic maculopathy was detected in 22 patients (11%). The disease duration of 6 to 15 years had the highest prevalence of Diabetic maculopathy. Significant risk factors for diabetic maculopathy were higher levels of HbA1c (p = 0.005), higher values of blood pressure (p = 0.001), higher cholesterol levels (p = 0.000), higher LDL-cholesterol levels (p = 0.000), higher triglyceride levels (p = 0.000), higher creatinine values (p = 0.000), higher urea values (p = 0.000), higher FBS levels (p = 0.020), higher PPBS levels (p = 0.001) and lower hemoglobin values (p = 0.000). CONCLUSION: Significant risk factors for diabetic maculopathy were higher levels of HbA1c, higher values of blood pressure, higher cholesterol levels, higher LDL-cholesterol levels, higher triglyceride levels, higher creatinine values, higher urea values, higher FBS levels, higher PPBS levels and lower hemoglobin values. However, smoking, drinking alcohol, dietary habits, HDL and BMI contributed as insignificant risk factors.Journal of Universal College of Medical Sciences (2016) Vol.04 No.01 Issue 13, Page: 16-21

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