scholarly journals Bioactive M(II) complexes of amino acid-based N3O donor mixed ligand: in vitro and in silico DNA binding studies

2017 ◽  
Vol 10 (3) ◽  
pp. 117-127 ◽  
Author(s):  
T. Daniel Prakash ◽  
V. Violet Dhayabaran
Keyword(s):  
Amino Acid ◽  
Dna Binding ◽  
In Silico ◽  
Mixed Ligand ◽  
Binding Studies ◽  
Dna Binding Studies

Synthesis, characterization, DNA binding studies and in vitro cytotoxicity of platinum(II)-dihalogenido complexes containing bidentate chelating N-donor ligands

2016 ◽  
Vol 69 (16) ◽  
pp. 2422-2436 ◽  
Author(s):  
Radka Křikavová ◽  
Ján Vančo ◽  
Tomáš Šilha ◽  
Jaromír Marek ◽  
Zdeněk Trávníček
Keyword(s):  
Dna Binding ◽  
In Vitro Cytotoxicity ◽  
Donor Ligands ◽  
Binding Studies ◽  
Dna Binding Studies

Photophysical properties and DNA binding studies of novel Eu 3+ mixed ligand complex

2016 ◽  
Vol 177 ◽  
pp. 416-424 ◽  
Author(s):  
Sneha R. Wankar ◽  
Umar Jan Pandit ◽  
Imran Khan ◽  
S.N. Limaye
Keyword(s):  
Dna Binding ◽  
Photophysical Properties ◽  
Mixed Ligand Complex ◽  
Mixed Ligand ◽  
Binding Studies ◽  
Ligand Complex ◽  
Dna Binding Studies

IN VITRO DNA BINDING STUDIES OF SELECTED HETEROCYCLIC COMPOUNDS

INDIAN DRUGS ◽  
2018 ◽  
Vol 55 (12) ◽  
pp. 24-26
Author(s):  
C Akhila ◽  
◽  
P Lalitha
Keyword(s):  
Dna Binding ◽  
Heterocyclic Compounds ◽  
Uv Spectroscopy ◽  
Binding Mode ◽  
Spectroscopic Technique ◽  
Binding Studies ◽  
Base Pairs ◽  
Dna Base ◽  
Dna Binding Studies

DNA binding studies of selected heterocyclic compounds belonging to the class of quinolinones, substituted quinolinones and thiones were carried out using ct-DNA. The binding nature of the compounds with DNA analyzed using UV-spectroscopy revealed the compounds to be DNA intercalators demonstrating the binding nature of compounds with DNA base pairs. This study is aimed at establishing a facile UV spectroscopic technique to arrive at the binding mode of DNA to ligands.

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