scholarly journals Tubulointerstitial damage as the major pathological lesion in endemic chronic kidney disease among farmers in North Central Province of Sri Lanka

2011 ◽  
Vol 17 (3) ◽  
pp. 213-221 ◽  
Author(s):  
Shanika Nanayakkara ◽  
Toshiyuki Komiya ◽  
Neelakanthi Ratnatunga ◽  
S. T. M. L. D. Senevirathna ◽  
Kouji H. Harada ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Sri Lanka ◽  
Kidney Disease ◽  
Central Province ◽  
North Central ◽  
Pathological Lesion ◽  
Tubulointerstitial Damage ◽  
North Central Province

scholarly journals The incidence, prevalence and trends of Chronic Kidney Disease and Chronic Kidney Disease of uncertain aetiology (CKDu) in the North Central Province of Sri Lanka: an analysis of 30,566 patients

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Asanga Venura Ranasinghe ◽  
Gardiye Weligamage Gamini Priyantha Kumara ◽  
Ranamuka Henayage Karunarathna ◽  
Ambepitiyawaduge Pubudu De Silva ◽  
Korale Gedara Dilini Sachintani ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Sri Lanka ◽  
Kidney Disease ◽  
Central Province ◽  
North Central ◽  
The North ◽  
North Central Province ◽  
Incidence Prevalence

scholarly journals Risk Factors Associated with Chronic Kidney Disease of Unknown Origin (Ckdu) in North Central Province (NCP) of Sri Lanka: An Analysis of Evidence to Date

2020 ◽  
pp. 1-4
Keyword(s):  
Chronic Kidney Disease ◽  
Sri Lanka ◽  
Kidney Disease ◽  
Rural Areas ◽  
Kidney Diseases ◽  
Unknown Origin ◽  
Central Province ◽  
North Central ◽  
Causative Factors ◽  
North Central Province

Chronic kidney disease of unknown origin (CKDu) is a global burden among the agricultural communities, this is a non-communicable disease (NCD) which is asymptomatic and irreversible until latter stages of the disease. The disease has no common features unlike chronic kidney diseases (CKD’s) making early detection impossible in the patients. The most recent form of CKDu was reported in India, known as the Indian CKDu in late 2010’s. In Sri Lanka, CKDu is highly prevalent in the north central province of the country with nearly15.1%-22.9% presented with the disease. This region is a dry-zone in which agricultural and farming activities are carried out as the main occupation. Several studies have been carried out linking CKDu to various factors such as heavy metals in water, agrochemicals, heat, dehydration and socio-demographics in NCP. Despite several researches being conducted none of them were able to prove the root cause and causative factors of the disease. Using the available articles online, studies from countries such as India, Nicaragua, Sri Lanka and South America were chosen in which heat stress, dehydration, heavy metal involvement, agrochemicals were common causative factors reported in these geographical locations. Several studies analyzed indicate that the affected CKDu population were part of the agricultural community in rural areas with less or no proper high school education and family history with CKDu. Recent findings do suggest that a combination study involving socio-demographical data and geographical data will help to end the CKDu debate worldwide and provide new insights into early diagnosis.

scholarly journals Compliance and adherence to drug treatment on patients with chronic kidney disease in high prevalence areas of North Central Province, Sri Lanka

2021 ◽  
Vol 8 (7) ◽  
pp. 3231
Author(s):  
Dilan Chathuranga ◽  
Harith S. Manathunga ◽  
Sumali K. Gunasekara ◽  
Kithsiri B. Jayasekara ◽  
Ashoka Sanjeewani
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Cross Sectional Study ◽  
Sri Lankan ◽  
Central Province ◽  
Cross Sectional ◽  
North Central ◽  
Time Period ◽  
Adherence Data ◽  
North Central Province

Background: Chronic kidney disease that cannot be explained by traditional factors such as hypertension, diabetes mellitus is called chronic kidney disease unexplained etiology. With limited evidence on the success of interventions in enhancing medication adherence, this study was designed to test patient compliance and adherence on taking medication in North Central Province in Sri Lanka.Methods: A cross sectional study was conducted in a selected area of NCP to identify compliance, adherence. Data was collected using an interviewer administered questionnaire by visiting patients at their own residences.Results: A total of 200 people participated in this study. 92.5% of the population was involved in agriculture and 63% worked more than 1 acre of farmland. Among the selected population (74%) were not educated about the side effects of medication. 60.5% had missed taking their medicines during the prescribed time period. The entire population of the study was selected among patients having a monthly income of less than 15,000 Sri Lankan rupees. There was a statistically significant association in missing doses with land extent, patient’s income and stages of the disease.Conclusions: Non adherence and compliance to the medication is common in patients that worked in largely extended lands, were in late stages of the disease and had reduced income. Compliance and Adherence to the medication can be enhanced by proper counseling and improving patient’s knowledge about their medication.

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