scholarly journals Analysis of the COVID-19 Vaccine Development Process: an Exploratory Study of Accelerating Factors and Innovative Environments

2021 ◽  
Author(s):  
Hugo Garcia Tonioli Defendi ◽  
Luciana da Silva Madeira ◽  
Suzana Borschiver
Keyword(s):  
Exploratory Study ◽  
Development Process ◽  
Vaccine Development ◽  
Innovative Environments

scholarly journals Prediction of Physicochemical Properties of SARS-CoV-2 Protein in Bangladesh

2020 ◽  
Author(s):  
Nilanjan Roy
Keyword(s):  
Physicochemical Properties ◽  
Development Process ◽  
Vaccine Development ◽  
Viral Proteins ◽  
Instability Index ◽  
Subunit Vaccines ◽  
Grand Average ◽  
Rapid Production ◽  
Aliphatic Index ◽  
Inactivated Vaccines

Awareness of the physicochemical properties of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is urgently required for the rapid production of live attenuated and inactivated vaccines. To develop subunit vaccines, it's also important to understand these properties for similar viral proteins. In this study, we predicted the physicochemical properties of SARS-CoV-2 protein that has been sequenced from Bangladeshi patients. Here we reported the number of amino acids, molecular weight, theoretical pI, amino acid composition, extinction coefficients, estimated half-life, instability index, aliphatic index, and grand average of hydropathicity of the SARS-CoV-2 protein in Bangladesh. As Bangladesh is consistently trying to contribute in the vaccine development process of SARS-CoV-2, we believe that this biocomputational study of physicochemical properties will give meaningful insights and will ease the way of vaccine development.

scholarly journals Quantifying the Impact of Public Perceptions on Vaccine Acceptance Using Behavioral Economics

2020 ◽  
Vol 8 ◽  
Author(s):  
Steven R. Hursh ◽  
Justin C. Strickland ◽  
Lindsay P. Schwartz ◽  
Derek D. Reed
Keyword(s):  
Behavioral Economics ◽  
Vaccine Efficacy ◽  
Development Process ◽  
Vaccine Development ◽  
Rapid Development ◽  
Public Perceptions ◽  
Mixed Effect ◽  
Behavioral Economic ◽  
Vaccine Acceptance ◽  
The Impact

This study was conducted to evaluate the impact of public perceptions of vaccine safety and efficacy on intent to seek COVID-19 vaccination using hypothetical vaccine acceptance scenarios. The behavioral economic methodology could be used to inform future public health vaccination campaigns designed to influence public perceptions and improve public acceptance of the vaccine. In June 2020, 534 respondents completed online validated behavioral economic procedures adapted to evaluate COVID-19 vaccine demand in relation to a hypothetical development process and efficacy. An exponential demand function was used to describe the proportion of participants accepting the vaccine at each efficacy. Linear mixed effect models evaluated development process and individual characteristic effects on minimum required vaccine efficacy required for vaccine acceptance. The rapid development process scenario increased the rate of decline in acceptance with reductions in efficacy. At 50% efficacy, 68.8% of respondents would seek the standard vaccine, and 58.8% would seek the rapid developed vaccine. Rapid vaccine development increased the minimum required efficacy for vaccine acceptance by over 9 percentage points, γ = 9.36, p < 0.001. Past-3-year flu vaccination, γ = −23.00, p < 0.001, and male respondents, γ = −4.98, p = 0.037, accepted lower efficacy. Respondents reporting greater conspiracy beliefs, γ = 0.39, p < 0.001, and political conservatism, γ = 0.32, p < 0.001, required higher efficacy. Male, γ = −4.43, p = 0.013, and more conservative, γ = −0.09, p = 0.039, respondents showed smaller changes in minimum required efficacy by development process. Information on the vaccine development process, vaccine efficacy, and individual differences impact the proportion of respondents reporting COVID-19 vaccination intentions. Behavioral economics provides an empirical method to estimate vaccine demand to target subpopulations resistant to vaccination.

scholarly journals We Don't Do Google, We Do Massive Attacks: Notes on Creative R&D Collaborations

Leonardo ◽  
2010 ◽  
Vol 43 (1) ◽  
pp. 94-95
Author(s):  
Jonathan Foster ◽  
Angela Lin ◽  
Ernest Edmonds
Keyword(s):  
Research And Development ◽  
Exploratory Study ◽  
Collaborative Research ◽  
Development Process ◽  
Creative Industries ◽  
Case Study Approach ◽  
Extensive Experience ◽  
Collective Case Study ◽  
Study Approach

The article presents findings from an exploratory study investigating the nature of collaborative research and development in creative industries. Participants in the study are two creative SMEs with extensive experience of participating in collaborative projects. A collective case study approach is adopted with data collected on the factors impinging on the effectiveness of such collaborations. Findings are presented at the macro and micro levels of such collaborations. The paper concludes with a summary of some of the challenges faced by small creative SMEs when collaborating with other organizations during the research and development process.

scholarly journals GeVaDSs – decision support system for novel Genetic Vaccine development process

2012 ◽  
Vol 13 (1) ◽  
pp. 91 ◽  
Author(s):  
Jacek Blazewicz ◽  
Marcin Borowski ◽  
Wahiba Chaara ◽  
Pawel Kedziora ◽  
David Klatzmann ◽  
...  
Keyword(s):  
Decision Support ◽  
Decision Support System ◽  
Support System ◽  
Development Process ◽  
Vaccine Development ◽  
Genetic Vaccine

scholarly journals Veterinary vaccine development: The helical project

2020 ◽  
Vol 4 (1) ◽  
pp. 042-047
Author(s):  
Dereja Iyasu Angani
Keyword(s):  
Production Process ◽  
Infection Prevention ◽  
Development Process ◽  
Vaccine Development ◽  
Vaccine Production ◽  
The Public ◽  
Health Implication ◽  
Veterinary Vaccine ◽  
Improper Use

Vaccine production process have been fuzzy journey to the public and, in some degrees, to those in the setting. By clearly showing the lengthy and challenging journey of vaccine development process, thereby suggesting the economic and health implication of improper use of veterinary vaccines, the paper tries to add the attention given to infection prevention. Starting from the foundations, the types and requirements of veterinary vaccines are described. The paper concludes with current research and regulatory quos in the topic.

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