Dietary inflammatory index and inflammatory gene interactions in relation to colorectal cancer risk in the Bellvitge colorectal cancer case–control study

Diet may modulate chronic inflammation. The aim of this study is to investigate whether the dietary inflammatory index (DII®) was associated with the risk of colorectal cancer in a Chinese population. A case-control study was conducted from July 2010 to April 2019, in Guangzhou, China. A total of 2502 eligible cases were recruited along with 2538 age- (5-year interval) and sex-matched controls. Dietary data derived from a validated food frequency questionnaire were used to calculate the energy-adjusted DII (E-DII) scores. Odds ratios (ORs) and 95% confidence intervals (CIs) for colorectal cancer risk were estimated using unconditional logistic regression models. In this study, E-DII scores ranged from −5.96 (the most anti-inflammatory score) to +6.01 (the most pro-inflammatory score). A positive association was found between the E-DII and colorectal cancer risk, with the OR = 1.40 (95% CI 1.16, 1.68; Ptrend < 0.01) for the highest E-DII quartile compared with the lowest quartile after adjusting for potential confounders. When stratified based on cancer subsite, sex, body mass index, and smoking status, significant associations were not observed in women or underweight individuals. Results from this study confirmed that a higher E-DII score was associated with an increased risk of colorectal cancer in a Chinese population.

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Survey on the association between eating habits, anthropometry and colorectal cancer: Case-control study in a population of eastern Algeria 2016-2017

Nutrition & Santé ◽

10.30952/ns.6.2.4 ◽

2017 ◽

Vol 06 (02) ◽

pp. 74-82

Author(s):

Samira NEGRICHI ◽

◽

Salima TALEB ◽

Sabiha BOUZBID ◽

Keyword(s):

Colorectal Cancer ◽

Case Control Study ◽

Eating Habits ◽

Case Control ◽

Cancer Case ◽

Colorectal Cancer Case ◽

Eastern Algeria ◽

Control Study

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Colorectal cancer: case-control study of sociodemographic, lifestyle and anthropometric parameters in Riyadh

Eastern Mediterranean Health Journal ◽

10.26719/2009.15.4.817 ◽

2009 ◽

Vol 15 (4) ◽

pp. 817-826 ◽

Cited By ~ 12

Author(s):

K.S. Almurshed

Keyword(s):

Colorectal Cancer ◽

Case Control Study ◽

Case Control ◽

Cancer Case ◽

Anthropometric Parameters ◽

Colorectal Cancer Case ◽

Control Study

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Dietary Inflammatory Index and Risk of Colorectal Cancer: A Case-Control Study in Korea

Nutrients ◽

10.3390/nu8080469 ◽

2016 ◽

Vol 8 (8) ◽

pp. 469 ◽

Cited By ~ 33

Author(s):

Young Cho ◽

Jeonghee Lee ◽

Jae Oh ◽

Aesun Shin ◽

Jeongseon Kim

Keyword(s):

Colorectal Cancer ◽

Case Control Study ◽

Case Control ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

Control Study

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A higher Dietary Inflammatory Index score is associated with a higher risk of breast cancer among Chinese women: a case–control study

British Journal Of Nutrition ◽

10.1017/s0007114517001192 ◽

2017 ◽

Vol 117 (10) ◽

pp. 1358-1367 ◽

Cited By ~ 19

Author(s):

Wu-Qing Huang ◽

Xiong-Fei Mo ◽

Yan-Bin Ye ◽

Nitin Shivappa ◽

Fang-Yu Lin ◽

...

Keyword(s):

Breast Cancer ◽

Breast Cancer Risk ◽

Cancer Risk ◽

Case Control Study ◽

Chinese Women ◽

Case Control ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

Increased Risk ◽

Control Study

AbstractPrevious studies have investigated the association between dietary inflammatory potential and the development of cancer. For breast cancer the results have been equivocal. The present study aimed to investigate whether higher Dietary Inflammatory IndexTM (DII) scores were associated with increased risk of breast cancer among Chinese women. A total of 867 cases and 824 controls were recruited into the present case–control study from September 2011 to February 2016. DII scores were computed based on baseline dietary intake assessed by a validated 81-item FFQ. The OR and 95 % CI were assessed by multivariable logistic regression after adjusting for various potential confounders. DII scores in this study ranged from −5·87 (most anti-inflammatory score) to +5·71 (most proinflammatory score). A higher DII score was associated with a higher breast cancer risk (adjusted ORquartile 4 v. 1 2·28; 95 % CI 1·71, 3·03; adjusted ORcontinuous 1·40; 95 %CI 1·25, 1·39). In stratified analyses, positive associations also were observed except for underweight women or women with either oestrogen receptor+ or progesterone receptor+ status (but not both). Results from this study indicated that higher DII scores, corresponding to more proinflammatory diets, were positively associated with breast cancer risk among Chinese women.

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Dietary inflammatory index and ovarian cancer risk in a New Jersey case–control study

Nutrition ◽

10.1016/j.nut.2017.08.011 ◽

2018 ◽

Vol 46 ◽

pp. 78-82 ◽

Cited By ~ 10

Author(s):

Nitin Shivappa ◽

James R. Hébert ◽

Lisa E. Paddock ◽

Lorna Rodriguez-Rodriguez ◽

Sara H. Olson ◽

...

Keyword(s):

Ovarian Cancer ◽

New Jersey ◽

Cancer Risk ◽

Case Control Study ◽

Case Control ◽

Ovarian Cancer Risk ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

Control Study

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Dietary inflammatory index and ovarian cancer risk in a large Italian case–control study

Cancer Causes & Control ◽

10.1007/s10552-016-0767-9 ◽

2016 ◽

Vol 27 (7) ◽

pp. 897-906 ◽

Cited By ~ 26

Author(s):

Nitin Shivappa ◽

James R. Hébert ◽

Valentina Rosato ◽

Marta Rossi ◽

Maurizio Montella ◽

...

Keyword(s):

Ovarian Cancer ◽

Cancer Risk ◽

Case Control Study ◽

Case Control ◽

Ovarian Cancer Risk ◽

Dietary Inflammatory Index ◽

Inflammatory Index ◽

Italian Case ◽

Control Study

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Dietary inflammatory index and endometrial cancer risk in an Italian case–control study

British Journal Of Nutrition ◽

10.1017/s0007114515004171 ◽

2015 ◽

Vol 115 (1) ◽

pp. 138-146 ◽

Cited By ~ 30

Author(s):

Nitin Shivappa ◽

James R. Hébert ◽

Antonella Zucchetto ◽

Maurizio Montella ◽

Diego Serraino ◽

...

Keyword(s):

Endometrial Cancer ◽

Cancer Risk ◽

Case Control Study ◽

Wide Spectrum ◽

Case Control ◽

Dietary Inflammatory Index ◽

Endometrial Cancer Risk ◽

Inflammatory Index ◽

Italian Case ◽

Control Study

AbstractThe relation between inflammation deriving from diet and endometrial cancer risk has not yet been investigated. In this study, we explored the association between the dietary inflammatory index (DII) and endometrial cancer risk in an Italian case–control study. Cases comprised 454 patients with incident, histologically confirmed carcinoma of the endometrium, and controls comprised 908 subjects admitted to the same network of hospitals as cases for a wide spectrum of acute, non-neoplastic conditions. DII scores were computed on the basis of dietary intake assessed using a reproducible and valid seventy-eight-item FFQ. OR were calculated through logistic regression models conditioned on age and study centre and adjusted for recognised confounding factors, including total energy intake. Women with the most pro-inflammatory diet had a higher risk for endometrial cancer compared with women with the most anti-inflammatory diet (ORQuartile 4 v. 1 1·46; 95 % CI 1·02, 2·11; Ptrend=0·04). A pro-inflammatory diet may increase the risk for endometrial cancer.

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