Pancreatic serous cystadenocarcinoma diagnosed with liver metastasis at 7 years after the resection of the primary serous neoplastic lesion

Author(s):  
Yutaka Takagi ◽  
Takashi Hatori ◽  
Osamu Itano ◽  
Masahiro Shinoda ◽  
Atsushi Kato ◽  
...  
Pancreatology ◽  
2015 ◽  
Vol 15 (6) ◽  
pp. 708-712
Author(s):  
Marcel Cerqueira Cesar Machado ◽  
Gilton Marques Fonseca ◽  
Luciana Rodrigues de Meirelles ◽  
Luiz Tenorio de Brito Siqueira ◽  
Betina Katz ◽  
...  

2021 ◽  
Vol 6 (4) ◽  
pp. 230-236
Author(s):  
Keval A Patel ◽  
Riddhi A Parmar ◽  
Jaimin M Patel ◽  
Bhawana S Sharma ◽  
Bimal Patel ◽  
...  

Ovarian pathology ranges from innocuous non-neoplastic lesions to malignant neoplastic entities. The incidence, clinical appearance and the behaviour of the different types of ovarian tumour is extremely variable. In order to have a better understanding of frequency and histomorphological patterns of different ovarian lesions study was encountered in our tertiary care hospital.To study the histopathology of ovarian non-neoplastic and neoplastic lesions and to study the distribution of ovarian lesions with respect to various parameters like age, bilaterality, gross and microscopic features.This is a prospective study of 125 ovarian specimens received in department of pathology, G.K. General Hospital, Bhuj during August 1, 2018 to July 31, 2020. Total 125 cases of ovarian specimens were studied, amongst them 58 were non-neoplastic and remaining 67 were neoplastic. The most common non-neoplastic lesion seen was follicular cysts 12 cases (21%), followed by endometriosis 9 cases (16%). Among 67 neoplastic ovarian lesions 58(87%) cases were benign, 3(4%) cases were borderline and 6 (9%) cases were malignant. In benign ovarian neoplasm, most commonly seen lesions were serous cystadenoma 24 cases (36%) followed by 13 cases (20%) of mature cystic teratoma. In malignant cases, maximum was of high-grade serous cystadenocarcinoma.Ovarian epithelial tumours are the most common type, while serous cystadenocarcinoma was the most common malignancy. Histological examination is gold standard and in certain difficult cases require immunohistochemistry.Ovary is an important reproductive organ with involvement in production of progeny.Ovarian pathology ranges from innocuous non-neoplastic lesions to malignant neoplastic entities. Ovarian neoplasms have become increasingly important not only because of the wide range of neoplasms, but also because they have gradually increased the mortality rate. The incidence, clinical appearance and the behaviour of the different types of ovarian tumour is extremely variable.


2001 ◽  
Vol 120 (5) ◽  
pp. A168-A168
Author(s):  
T KAIHARA ◽  
T KUSAKA ◽  
H KAWAMATA ◽  
Y ODA ◽  
J IMURA ◽  
...  

Swiss Surgery ◽  
2000 ◽  
Vol 6 (4) ◽  
pp. 164-168 ◽  
Author(s):  
Seiler ◽  
Redaelli ◽  
Schmied ◽  
Baer ◽  
Büchler

Neue Erkenntnisse über die Anatomie und Funktion der Leber haben dazu geführt, dass heute die chirurgische Resektion die Therapie der Wahl bei Lebermetastasen geworden ist. Obschon Lebermetastasen ein fortgeschrittenes Tumorstadium bedeuten, werden infolge besserer Kenntnisse der Karzinogenese (Mikrometastasen etc.) sowie der prognostischen Risikofaktoren erwiesenermassen die besten Langzeitresultate durch die chirurgische Resektion erzielt. In dieser Studie wurden die Ergebnisse von 109 Resektionen von kolorektalen sowie nicht kolorektalen Lebermetastasen an unserer Klinik während eines Zeitraumes von 59 Monaten zusammengefasst. Vier verschiedene Operationsverfahren (formelle Hemihepatektomie vs Segmentresektion vs atypische Resektion vs Biopsie) wurden untersucht. Die Einhaltung eines Resektionsabstandes von mindestens 10 mm wurde bei Resektionen immer angestrebt. Die kumulierte Morbidität aller Operationsverfahren zusammen betrug 23%. Obwohl die Morbidität bei ausgedehnten Resektionen höher war (Encephalopathie 16% vs 2.3% bei der Segmentresektion, Leberinsuffizienz 23% vs 4.7%), war das Langzeitüberleben gegenüber den limitierten Resektionsverfahren verbessert. Die 60-Tage Mortalität lag bei 2.7%. Patienten nach Resektion von kolorektalen Lebermetastasen hatten eine höhere Ueberlebensrate als diejenigen nach Resektion nicht kolorektaler Metastasen. Unsere Resultate zeigen, dass die Leberresektion heutzutage unter Einhaltung der anatomischen sowie funktionellen Grenzen (inkl. eines adäquaten Resektionsrandes) die einzige, potentiell kurative Therapie von Lebermetastasen darstellt. Trotz erhöhter perioperativer Morbidität ist die ausgedehnte formelle Resektion den limitierten Operationsverfahren bezüglich Langzeitüberleben überlegen. Ein Grund dafür ist die erhöhte Wahrscheinlichkeit einer Mitresektion von präoperativ nicht detektierbaren lokalen Mikrometastasen.


2019 ◽  
Author(s):  
M Niederreiter ◽  
L Niederreiter ◽  
A Schmiderer ◽  
H Zoller ◽  
H Tilg ◽  
...  

2009 ◽  
Vol 15 (2) ◽  
pp. 201 ◽  
Author(s):  
Eun Hyoung Jeong ◽  
Dong Hyun Kim ◽  
Sung Ho Ma ◽  
Eui Jong Chung ◽  
Sang Su Bae ◽  
...  

2020 ◽  
Author(s):  
Lungwani Muungo

A 72-year-old woman with a sigmoid colon cancer anda synchronous colorectal liver metastasis (CRLM), whichinvolved the right hepatic vein (RHV) and the inferiorvena cava (IVC), was referred to our hospital. Themetastatic lesion was diagnosed as initially unresectablebecause of its invasion into the confluence of theRHV and IVC. After she had undergone laparoscopicsigmoidectomy for the original tumor, she consequentlyhad 3 courses of modified 5-fluorouracil, leucovorin,and oxaliplatin (mFOLFOX6) plus cetuximab. Computedtomography revealed a partial response, and theconfluence of the RHV and IVC got free from cancerinvasion. After 3 additional courses of mFOLFOX6 pluscetuximab, preoperative percutaneous transhepaticportal vein embolization (PTPE) was performed tosecure the future remnant liver volume. Finally, a righthemihepatectomy was performed. The postoperativecourse was uneventful. The patient was dischargedfrom the hospital on postoperative day 13. She hadneither local recurrence nor distant metastasis 18 moafter the last surgical intervention. This multidisciplinarystrategy, consisting of conversion chemotherapy usingFOLFOX plus cetuximab and PTPE, could contributein facilitating curative hepatic resection for initiallyunresectable CRLM.Key words: Initially unresectable; Colorectal liver metastasis;Conversion chemotherapy; Cetuximab; Percutaneoustranshepatic portal vein embolization


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