Combined effect of antioxidant supplementation and resistance training on oxidative stress markers, muscle and body composition in an elderly population

2011 ◽  
Vol 15 (10) ◽  
pp. 883-889 ◽  
Author(s):  
F. Bobeuf ◽  
M. Labonte ◽  
I. J. Dionne ◽  
Abdelouahed Khalil
2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Bruno Bavaresco Gambassi ◽  
Hélio José Coelho-Junior ◽  
Camila Paixão dos Santos ◽  
Ivan de Oliveira Gonçalves ◽  
Cristiano Teixeira Mostarda ◽  
...  

Stroke survivors are at substantial risk of recurrent cerebrovascular event or cardiovascular disease. Exercise training offers nonpharmacological treatment for these subjects; however, the execution of the traditional exercise protocols and adherence is constantly pointed out as obstacles. Based on these premises, the present study investigated the impact of an 8-week dynamic resistance training protocol with elastic bands on functional, hemodynamic, and cardiac autonomic modulation, oxidative stress markers, and plasma nitrite concentration in stroke survivors. Twenty-two patients with stroke were randomized into control group (CG, n=11) or training group (TG, n=11). Cardiac autonomic modulation, oxidative stress markers, plasma nitrite concentration, physical function and hemodynamic parameters were evaluated before and after 8 weeks. Results indicated that functional parameters (standing up from the sitting position (P=0.011) and timed up and go (P=0.042)) were significantly improved in TG. Although not statistically different, both systolic blood pressure (Δ=−10.41 mmHg) and diastolic blood pressure (Δ=−8.16 mmHg) were reduced in TG when compared to CG. Additionally, cardiac autonomic modulation (sympathovagal balance–LF/HF ratio) and superoxide dismutase were improved, while thiobarbituric acid reactive substances and carbonyl levels were reduced in TG when compared to the CG subjects. In conclusion, our findings support the hypothesis that dynamic resistance training with elastic bands may improve physical function, hemodynamic parameters, autonomic modulation, and oxidative stress markers in stroke survivors. These positive changes would be associated with a reduced risk of a recurrent stroke or cardiac event in these subjects.


2014 ◽  
Vol 6 (1) ◽  
pp. 60-64
Author(s):  
Md Rizman Md Lazin @ Md Lazim ◽  
Rahimah Zakaria ◽  
Rohana Abdul Jalil ◽  
Wan Suriati Wan Nik ◽  
Che Badariah Abdul Aziz ◽  
...  

The main objective of the present study was to evaluate the association of changes in body composition with changes in systemic oxidative stress markers among obese adults participating in a weight loss program. Thirty four obese adults were recruited from the Obesity Clinic, Hospital Universiti Sains Malaysia (USM) to voluntarily participate in a weight loss program comprising of physical exercise and dietary modification. Levels/activities of oxidative stress markers were measured before and after the program. Mean body weight, body mass index (BMI), waist circumference (WC), hip circumference (HC) and percentage of body fat mass decreased significantly while mean body lean mass and body water increased significantly after the weight loss program. Plasma glutathione peroxidase (GPx) activity and 4- hydroxynonenal (4-HNE) concentration increased significantly while other enzymatic antioxidant activities such as catalase (CAT) and superoxide dismutase (SOD) were not significantly increased. The ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG) was significantly decreased. There was no significant association between changes in body composition and changes in systemic oxidative stress markers among obese adults. In conclusion, changes in body composition were not associated with changes in systemic oxidative stress markers among obese adults.


Antioxidants ◽  
2020 ◽  
Vol 9 (10) ◽  
pp. 941
Author(s):  
Luana Santos Costa ◽  
Felipe J. Aidar ◽  
Dihogo Gama de Matos ◽  
José Uilien de Oliveira ◽  
Jymmys Lopes dos Santos ◽  
...  

The objective of this study was to analyze the effects of the combination of resistance training (RT) and the hydroethanolic extract (EHE) of Bowdichia virgilioides as markers of oxidative stress (OS) in rats with peripheral nerve injury (PNI). Rats were allocated into six groups (n = 10): animals without interventions (C), animals with an exposed nerve but without injury, injured animals, trained and injured animals, injured animals that received EHE, and animals that received a combination of RT and EHE. RT comprised the climbing of stairs. EHE was orally administered (200 mg/kg) for 21 days after PNI induction. RT reduced the amount of lipoperoxidation in plasma (14.11%). EHE reduced lipoperoxidation in the plasma (20.72%) and the brain (41.36). RT associated with the extract simultaneously reduced lipoperoxidation in the plasma (34.23%), muscle (25.13%), and brain (43.98%). There was an increase in total sulhydrilyl levels (a) in the brain (33.33%) via RT; (b) in the brain (44.44%) and muscle (44.51%) using EHE; and (c) in the plasma (54.02%), brain (54.25%), and muscle using the combination of RT + EHE. These results suggest that RT associated with oral EHE results in a decrease in OS.


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