Association of genetic variants of xenobiotic and estrogen metabolism pathway (CYP1A1 and CYP1B1) with gallbladder cancer susceptibility

Tumor Biology ◽  
2014 ◽  
Vol 35 (6) ◽  
pp. 5431-5439 ◽  
Author(s):  
Kiran Lata Sharma ◽  
Akash Agarwal ◽  
Sanjeev Misra ◽  
Ashok Kumar ◽  
Vijay Kumar ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Cancer Susceptibility ◽  
Estrogen Metabolism ◽  
Metabolism Pathway

Association of cancer stem cell markers genetic variants with gallbladder cancer susceptibility, prognosis, and survival

Tumor Biology ◽  
2015 ◽  
Vol 37 (2) ◽  
pp. 1835-1844 ◽  
Author(s):  
Anu Yadav ◽  
Annapurna Gupta ◽  
Neeraj Rastogi ◽  
Sushma Agrawal ◽  
Ashok Kumar ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Cancer Susceptibility ◽  
Stem Cell Markers ◽  
Cell Markers ◽  
Cancer Stem Cell Markers

Association of genetic variants of cancer stem cell gene CD44 haplotypes with gallbladder cancer susceptibility in North Indian population

Tumor Biology ◽  
2013 ◽  
Vol 35 (3) ◽  
pp. 2583-2589 ◽  
Author(s):  
Kiran Lata Sharma ◽  
Anu Yadav ◽  
Annapurna Gupta ◽  
Sonam Tulsayan ◽  
Vijay Kumar ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cancer Stem Cell ◽  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Indian Population ◽  
Cancer Susceptibility ◽  
North Indian Population ◽  
Cell Gene ◽  
Stem Cell Gene

Association of liver X receptors (LXRs) genetic variants to gallbladder cancer susceptibility

Tumor Biology ◽  
2013 ◽  
Vol 34 (6) ◽  
pp. 3959-3966 ◽  
Author(s):  
Kiran Lata Sharma ◽  
Sanjeev Misra ◽  
Ashok Kumar ◽  
Balraj Mittal
Keyword(s):  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Cancer Susceptibility ◽  
Liver X Receptors ◽  
X Receptors

scholarly journals ALDH3B2 Polymorphism Is Associated with Colorectal Cancer Susceptibility

2020 ◽  
Vol 2020 ◽  
pp. 1-5 ◽  
Author(s):  
Zhi-Gang Gao ◽  
Yong Yang ◽  
Xiao-Feng Han ◽  
Yun-Lei Wang ◽  
Zhen-Jun Wang
Keyword(s):  
Colorectal Cancer ◽  
Genetic Variants ◽  
Protein Function ◽  
Odds Ratio ◽  
Functional Annotation ◽  
Cancer Susceptibility ◽  
Alcohol Metabolism ◽  
Metabolism Pathway ◽  
Metabolic Genes ◽  
Coding Variants

Colorectal cancer (CRC) is the 5th leading cancer in China. Alcohol consumption has been reported to be one of the risk factors of CRC. However, it remains unclear whether genetic variants of alcohol metabolic genes are associated with CRC risk. In this study, we tested the coding variants in the alcohol metabolic genes and the risk of CRC, by using 485 cases and 516 controls. A total of 16 germline coding variants in 10 alcohol metabolic genes were genotyped. We identified that rs3741178 in ALDH3B2 was significantly associated with CRC risk with odds ratio being 2.13 (95% CI: 1.24–3.68, P=0.0064). Further functional annotation suggested that this variant may damage the protein function of ALDH3B2. Our results suggested that ALDH3B2 in the alcohol metabolism pathway contributed to the development of CRC, which may contribute to the prevention of this disease in the future.

scholarly journals Evaluation of genetic variants of DNA repair pathway genes in gallbladder cancer susceptibility and treatment outcome

HPB ◽  
2016 ◽  
Vol 18 ◽  
pp. e476-e477
Author(s):  
A. Kumar ◽  
A. Sharma ◽  
A. Gupta ◽  
A. Yadava ◽  
B. Mittal
Keyword(s):  
Dna Repair ◽  
Treatment Outcome ◽  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Cancer Susceptibility ◽  
Repair Pathway

Association of Wnt signaling pathway genetic variants in gallbladder cancer susceptibility and survival

Tumor Biology ◽  
2015 ◽  
Vol 37 (6) ◽  
pp. 8083-8095 ◽  
Author(s):  
Anu Yadav ◽  
Annapurna Gupta ◽  
Saurabh Yadav ◽  
Neeraj Rastogi ◽  
Sushma Agrawal ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Gallbladder Cancer ◽  
Signaling Pathway ◽  
Genetic Variants ◽  
Cancer Susceptibility ◽  
Wnt Signaling Pathway

Association of Potentially Functional Genetic Variants of PLCE1 with Gallbladder Cancer Susceptibility in North Indian Population

2013 ◽  
Vol 44 (4) ◽  
pp. 436-443 ◽  
Author(s):  
Kiran Lata Sharma ◽  
Meenakshi Umar ◽  
Manmohan Pandey ◽  
Sanjeev Misra ◽  
Ashok Kumar ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Indian Population ◽  
Cancer Susceptibility ◽  
North Indian Population

scholarly journals Association of miR-27a, miR-181a and miR-570 genetic variants with gallbladder cancer susceptibility on North indian population

2014 ◽  
Vol 7 (Suppl 1) ◽  
pp. P17 ◽  
Author(s):  
Annapurna Gupta ◽  
Kiran L Sharma ◽  
Annu Yadav ◽  
Vijay Kumar ◽  
Sanjeev Misra ◽  
...  
Keyword(s):  
Gallbladder Cancer ◽  
Genetic Variants ◽  
Indian Population ◽  
Cancer Susceptibility ◽  
North Indian Population
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