scholarly journals Diagnosis and Management of Gaucher Disease in India – Consensus Guidelines of the Gaucher Disease Task Force of the Society for Indian Academy of Medical Genetics and the Indian Academy of Pediatrics

2018 ◽  
Vol 55 (2) ◽  
pp. 143-153
Author(s):  
Ratna Dua Puri ◽  
◽  
Seema Kapoor ◽  
Priya S. Kishnani ◽  
Ashwin Dalal ◽  
...  
2018 ◽  
Vol 20 (6) ◽  
pp. NP1-NP1

Samantha S Taylor, Andrew H Sparkes, Katherine Briscoe, Jenny Carter, Salva Cervantes Sala, Rosanne E Jepson, Brice S Reynolds and Brian A Scansen J Feline Med Surg 2017; 19: 288–303 Readers should note that the version of the guidelines that appeared in print in March 2017 and online until May 2018 has been amended. The version now appearing online is the correct one. For information, the following amendment has been made to the original published version. In Table 6 on page 299 the unit for esmolol should have been μg/kg/min and not mg/kg/min, as stated. The ‘Suggested dose’ column entry for esmolol has therefore been amended to ‘50–100 μg/kg/min CRI’.


PEDIATRICS ◽  
1986 ◽  
Vol 78 (5) ◽  
pp. 959-982
Author(s):  
Jerome O. Klein ◽  
Ralph D. Feigin ◽  
George H. McCracken

Children still die or suffer permanent neurologic sequelae as a result of bacterial meningitis. Prompt diagnosis and aggressive management are the goals, but early signs of meningitis are often subtle and nonspecific and, therefore, may be recognized only in retrospect. The physician must identify among the many febrile children seen every day in office practice—most of whom have spontaneously resolving illnesses usually caused by viruses—the few children who have serious bacterial infection requiring early intervention. No single test or battery of tests replaces the clinical acumen of the physician in identifying the child with early signs of bacterial meningitis. Because of controversies about diagnosis and treatment of meningitis voiced in various forums, including the courtroom, the Task Force on Diagnosis and Management of Meningitis has been asked by the Executive Board of the American Academy of Pediatrics to prepare a report on the causes, diagnosis, management, and outcome of meningitis in infants and children. This task force selected for discussion issues of current relevance and controversy in the diagnosis and treatment of bacterial and nonbacterial meningitis. Many other aspects of meningitis are discussed elsewhere. Commentaries on the prevention of disease by chemoprophylaxis (antimicrobial agents) or immunoprophylaxis (vaccines) have been prepared by the Committee on Infectious Diseases of the American Academy of Pediatrics. In addition the Morbidity and Mortality Weekly Report (Centers for Disease Control, Atlanta) publishes recommendations on vaccine usage and chemoprophylaxis formulated by the Advisory Committee on Immunization Practices. These resources are of value to the practitioner who cares for children and needs information on optimal measures for the treatment and prevention of meningitis.


2020 ◽  
Vol 33 (7) ◽  
Author(s):  
Swathi Eluri ◽  
Edward G A Iglesia ◽  
Michael Massaro ◽  
Anne F Peery ◽  
Nicholas J Shaheen ◽  
...  

Summary Real-world practice patterns of eosinophilic esophagitis (EoE) among gastroenterologists are not well-described. The aim is to describe practice patterns of EoE diagnosis and management and assess concordance with consensus guidelines. We conducted a cross-sectional online survey of gastroenterologists in the USA using Qualtrics, which was dispersed through the North Carolina Society of Gastroenterology (NCSG) and the American College of Gastroenterology member listservs. A similar survey was sent to NCSG members in 2010 and responses were compared in a subanalysis. Of 240 respondents, 37% (n = 80) worked in an academic setting versus 63% (n = 138) community practice setting. Providers saw a median of 18 (interquartile range 2–100) EoE patients annually and 24% (n = 52) were ‘very familiar’ with EoE guidelines. A proton-pump inhibitor (PPI) trial was required by 37% of providers prior to EoE diagnosis. In total, 60% used a ≥15 eosinophils per high-power field cut point for diagnosis and 62% biopsied from the proximal and distal esophagus on initial exam. Only 12% (n = 28) followed EoE diagnosis guidelines. For first-line treatment, 7% used dietary therapy, 32% topical steroids, and 61% used PPIs; 67% used fluticasone as first-line steroid; 41% used maintenance steroid treatment in responders. In the NCSG cohort, a higher proportion in 2017 followed guideline diagnosis recommendations compared with 2010 (14% vs. 3%; P = 0.03) and a higher proportion used dietary therapy as first-line treatment (13% vs. 3%; P = 0.046). There is variability in EoE practice patterns for EoE management, with management differing markedly from consensus guidelines. Further education and guideline dissemination are needed to standardize practice.


Reumatismo ◽  
2019 ◽  
Vol 71 (S1) ◽  
pp. 50-79
Author(s):  
N. Ughi ◽  
I. Prevete ◽  
R. Ramonda ◽  
L. Cavagna ◽  
G. Filippou ◽  
...  

Gout is a chronic disease with an increased risk of premature death related to comorbidities. Treatment of gout has proved suboptimal and clinical practice guidelines (CPGs) are expected to have a key role in achieving improvement. Since new evidence has become available, the Italian Society for Rheumatology (SIR) has been prompted to update the 2013 recommendations on the diagnosis and management of gout. The framework of the Guidelines International Network Adaptation Working Group was adopted to identify, appraise (AGREE II), synthesize, and customize the existing gout CPGs to the needs of the Italian healthcare context. The task force consisting of rheumatologists from the SIR Epidemiology Unit and a committee with experience on gout identified key health questions to guide a systematic literature review. The target audience includes physicians and health professionals who manage gout in practice, and the target population includes adult patients suspected or diagnosed as having gout. These recommendations were finally rated by an external multi-disciplinary commission. From a systematic search in databases (Medline, Embase) and grey literature, 8 CPGs were selected and appraised by two independent raters. Combining evidence and statements from these CPGs and clinical expertise, 14 recommendations were developed and graded according to the level of evidence. The statements and potential impact on clinical practice were discussed and assessed. These revised recommendations are intended to provide guidance for the diagnosis and the treatment of gout and to disseminate the best evidence-based healthcare for this disease.


2019 ◽  
Vol 56 (3) ◽  
pp. 221-228 ◽  
Author(s):  
Anupam Sachdeva ◽  
Prachi Jain ◽  
Vinod Gunasekaran ◽  
Sunita Bijarnia Mahay ◽  
Sharmila Mukherjee ◽  
...  

1998 ◽  
Vol 81 (5) ◽  
pp. 478-518 ◽  
Author(s):  
Mark S Dykewicz ◽  
Stanley Fineman ◽  
David P Skoner ◽  
Richard Nicklas ◽  
Rufus Lee ◽  
...  

2015 ◽  
Vol 135 (2) ◽  
pp. AB279 ◽  
Author(s):  
Jonathan M. Spergel ◽  
Anna H. Nowak-Wegrzyn ◽  
Fallon Schultz ◽  
Marion E. Groetch ◽  
Marisa Conte ◽  
...  

2006 ◽  
Vol 13 (9) ◽  
pp. 923-929 ◽  
Author(s):  
C. Angelini ◽  
A. Federico ◽  
H. Reichmann ◽  
A. Lombes ◽  
P. Chinnery ◽  
...  

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