scholarly journals Association of Human bocavirus with Respiratory Infections in Outpatients and in Patients Attended at a Reference Hospital

2011 ◽  
Vol 22 (2) ◽  
Author(s):  
Irene Pedrosa-Corral ◽  
Mercedes Pérez-Ruiz ◽  
José-María Navarro-Marí ◽  
Alfonso Ruiz-Bravo
2012 ◽  
Vol 54 (6) ◽  
pp. 307-310 ◽  
Author(s):  
Elaine Regina Baptista Caccia ◽  
Aripuana Sakurada Aranha Watanabe ◽  
Emerson Carraro ◽  
Elcio Leal ◽  
Celso Granato ◽  
...  

BACKGROUND AND OBJECTIVES: Human Bocavirus (HBoV) has been described since 2005 as an etiological agent of respiratory virus infections. From 2001 to 2008 we investigated the etiology of HBoV among adults and children in different groups at risk of presenting complications arising from acute respiratory infection, the investigation was carried out in a tertiary hospital health care system in Brazil. METHODS: HBoV DNA was assayed in 598 respiratory samples from community and hospitalized patients by PCR. RESULTS: Of the 598 tested samples, 2.44% (8/328) of children, including five children with heart disease, and 0.4% (1/270) of adult bone-marrow-transplant were HBoV positive. CONCLUSIONS: These data suggested lower HBoV frequency among different at-risk patients and highlights the need to better understand the real role of HBoV among acute respiratory symptomatic patients.


2018 ◽  
Vol 84 (7) ◽  
Author(s):  
G. La Rosa ◽  
G. Purpari ◽  
A. Guercio ◽  
S. Di Bella ◽  
F. Gucciardi ◽  
...  

ABSTRACTHuman bocavirus (HBoV) has been shown to be a common cause of respiratory infections and gastroenteritis in children. Recently, HBoVs have been detected in sewage and river waters in Italy and worldwide. However, studies on their presence in other water environments and in bivalve mollusks are not yet available. In this study, 316 bivalve shellfish samples collected in three Italian regions over a 6-year period (2012 to 2017) were analyzed by nested PCR and sequencing using broad-range primer pairs targeting the capsid proteins VP1 and VP2 of HBoV. The virus was detected in 27 samples (8.5% of the total samples), and a statistically significant difference was found within the three regions. A further 13 samples, collected in geographic and temporal proximity to positive samples, were included in the study to assess the spread of HBoV in shellfish production areas at the time of contamination. Twelve of these additional samples were found to be positive for HBoV. All positive samples in this study were characterized as HBoV species 2 (17 samples; 8 different sequences) or species 3 (22 samples; 4 different sequences). This study reports the occurrence of HBoV in bivalve shellfish and shows evidence of considerable spatial spread of the virus throughout shellfish production areas. Further studies are needed to elucidate both the role of HBoV as an agent of gastroenteritis and the risk for foodborne transmission of this virus.IMPORTANCEHuman bocavirus is recognized as an important cause of acute respiratory tract infections and has recently been considered an etiological agent of gastroenteritis in the pediatric population. Our findings document that HBoVs are detected in bivalve shellfish with a relevant prevalence and suggest that an assessment of the risk for foodborne transmission of these viruses should be undertaken.


2020 ◽  
Vol 95 ◽  
pp. 32-37 ◽  
Author(s):  
Gabriel Azevedo Alves Leitão ◽  
Alberto Ignácio Olivares Olivares ◽  
Yan Cardoso Pimenta ◽  
Isabella Fernandes Delgado ◽  
Marize Pereira Miagostovich ◽  
...  

2007 ◽  
Vol 79 (5) ◽  
pp. 539-543 ◽  
Author(s):  
Mohammadreza Naghipour ◽  
Luis E. Cuevas ◽  
Tahereh Bakhshinejad ◽  
Winifred Dove ◽  
C. Anthony Hart

2018 ◽  
Vol 17 (4) ◽  
pp. 4-12
Author(s):  
V. V. Shkarin ◽  
O. V. Kovalyshen ◽  
R. F. Chanysheva ◽  
A. V. Sergeeva ◽  
A. A. Rassokhin

The review article summarizes and systematizes scientific data on the pathogens of new respiratory infections discovered in the early XXI century – Human metapneumovirus (HMPV), Human bocavirus (HBoV), Human coronavirus (HCoV). Groups of microorganisms with which they act as associates are identified: other viruses (HMPV – HRSV, Rhinovirus, Adenovirus, HCoV; НBoV– Rhinovirus, HRSV, Rotavirus, Norovirus; HCoV – Influenza virus, Adenovirus and HRSV), and also some bacteria (HMPV – S. pneumoniae, H. influenzae type b; НBoV – S. enteritidis, C. jejune; HCoV – M. pneumoniae, K. pneumoniae). The clinical and epidemiological features of combined forms of infections are analyzed: predominance of moderate course, with risk of complications, risk groups (young children), seasonality (autumn-winter). The complexity of verification of these infections from other viral infections based on the clinical picture is established.


2020 ◽  
pp. 42-47
Author(s):  
N. G. Kolosova ◽  
I. V. Grebeneva ◽  
V. D. Denisova ◽  
E. M. Maksimova

Acute respiratory tract infections accompanied by cough play a significant role in respiratory pathology in childhood. The incidence of acute respiratory infections among children is 4–5 times higher than among the adult population and accounts for more than 90% of all infectious and parasitic diseases registered in Russia. The highest rates of acute respiratory infections are observed among children of preschool age, especially in the first three years of life. As in adults, children’s cough, described as a symptom of «upper respiratory infection» or «acute bronchitis», is the most commonly diagnosed acute manifestation in primary care. These 2 diagnoses represent 75% of all cough cases. The most common etiological agents in acute bronchitis are respiratory viruses: adenovirus, influenza viruses and parainfluenza viruses, respiratory syncytial virus, rhinovirus, human Bocavirus, Coxsackievirus, herpes simplex virus, etc. Drug therapy for coughing is prescribed when there is a nonproductive cough that does not perform its protective function, meaning it does not contribute to the purification of the respiratory tract, and is aimed at dilution of sputum, reducing its adhesiveness (viscosity) and thus increase the effectiveness of coughing. The main groups of mucoactive drugs that are usually considered in this case are mucolytics, mucoregulators, mucokinetics, expectorants, and combination drugs. Combination drugs created to eliminate various elements of pathogenesis of respiratory diseases, accompanied by a nonproductive cough and bronchoobstruction, deserve close attention due to the possibility of using several active substances in fixed drug combinations with accurate dosages and proven clinical effectiveness, reducing the number of simultaneously taken drugs, reducing the risk of developing undesirable events. Oral administration of combined medicines becomes especially important in conditions when inhalation therapy is impossible.


2015 ◽  
Vol 144 (3) ◽  
pp. 527-536 ◽  
Author(s):  
D. N. TRAN ◽  
Q. D. TRINH ◽  
N. T. K. PHAM ◽  
M. P. VU ◽  
M. T. HA ◽  
...  

SUMMARYInformation about viral acute respiratory infections (ARIs) is essential for prevention, diagnosis and treatment, but it is limited in tropical developing countries. This study described the clinical and epidemiological characteristics of ARIs in children hospitalized in Vietnam. Nasopharyngeal samples were collected from children with ARIs at Ho Chi Minh City Children's Hospital 2 between April 2010 and May 2011 in order to detect respiratory viruses by polymerase chain reaction. Viruses were found in 64% of 1082 patients, with 12% being co-infections. The leading detected viruses were human rhinovirus (HRV; 30%), respiratory syncytial virus (RSV; 23·8%), and human bocavirus (HBoV; 7·2%). HRV was detected all year round, while RSV epidemics occurred mainly in the rainy season. Influenza A (FluA) was found in both seasons. The other viruses were predominant in the dry season. HRV was identified in children of all age groups. RSV, parainfluenza virus (PIV) 1, PIV3 and HBoV, and FluA were detected predominantly in children aged <6 months, 6–12 months, 12–24 months, and >24 months, respectively. Significant associations were found between PIV1 with croup (P < 0·005) and RSV with bronchiolitis (P < 0·005). HBoV and HRV were associated with hypoxia (P < 0·05) and RSV with retraction (P < 0·05). HRV, RSV, and HBoV were detected most frequently and they may increase the severity of ARIs in children.


2019 ◽  
Vol 66 (4) ◽  
pp. 485-497 ◽  
Author(s):  
Mehrdad Mohammadi ◽  
Jila Yavarian ◽  
Vajihe Karbasizade ◽  
Sharareh Moghim ◽  
Bahram Nasr Esfahani ◽  
...  

2013 ◽  
Vol 86 (6) ◽  
pp. 988-994 ◽  
Author(s):  
Dinh Nguyen Tran ◽  
Tran Quynh Nhu Nguyen ◽  
Tuan Anh Nguyen ◽  
Satoshi Hayakawa ◽  
Masashi Mizuguchi ◽  
...  

2007 ◽  
Vol 195 (5) ◽  
pp. 675-679 ◽  
Author(s):  
Luciano Kleber de Souza Luna ◽  
Marcus Panning ◽  
Klaus Grywna ◽  
Susanne Pfefferle ◽  
Christian Drosten

Abstract Respiratory infections after air travel are frequent, but epidemiological data are incomplete. Using sensitive polymerase chain reactions, we studied the spectrum of atypical bacteria and respiratory viruses in travelers fulfilling the case definition of severe acute respiratory syndrome. A pathogen was identified in 67 travelers (43.2%). Influenza and parainfluenza viruses were most prevalent, at 14.2% and 15.5%, respectively. Prevalences of adenoviruses, human metapneumovirus, coronaviruses, and rhinoviruses ranged between 2.6% and 4.8%. Human bocavirus, respiratory syncytial virus, and Legionella, Mycoplasma, and Chlamydophila species were absent or appeared at frequencies of &lt;1%. To our knowledge, these are the first specific baseline data for the mentioned agents in the context of air travel.


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